Special

MmuEX0019230 @ mm9

Exon Skipping

Gene
ENSMUSG00000014778 | Fhod1
Description
formin homology 2 domain containing 1 [Source:MGI Symbol;Acc:MGI:2679008]
Coordinates
chr8:107853469-107854187:-
Coord C1 exon
chr8:107853995-107854187
Coord A exon
chr8:107853747-107853909
Coord C2 exon
chr8:107853469-107853669
Length
163 bp
Sequences
Splice sites
3' ss Seq
ACCCTTCTTTCCCTGTCTAGACA
3' ss Score
10.09
5' ss Seq
GAGGTAGGG
5' ss Score
7.81
Exon sequences
Seq C1 exon
GTTCCATGCCTTCCTGCTCTACCTGGGCTACACCCCACAGGCAGCAAGGGATGTACGCATCATGCAGTTCTGCCACACACTGAGAGAGTTTGCCCTTGAGTATCGGACTTGTCGGGAACGGGTACTGCAGCAGCAGCAGAAGCGGGCTACATACCGTGAGCGCAACAAGACCCGTGGTCGCATGATTACCGAG
Seq A exon
ACAGAGAAGTTCTCAGGTGTGGCTGGGGAGGCCCCCAATAACCTGTCTGTCCCAGTGGCTGTGGGCAGCGGGCCAGGTCAGGGTGATACTGACAATCATGCCAGCATGAAGAGCCTGCTTACCAGCAGGCCGGAAGATGCCACACACAGCCGACGCAGCAGAG
Seq C2 exon
GTATGGTCCAGAGCAGTTCCCCCGTCTCACACACAGCAGTGGGGCCCTCCGCTGCATCCCCTGAGGAGACTGCAGCCTCCGGCTTACCCACCGACACGTCAGATGAGATAATGGACCTGCTGGTGCAGTCAGTTACCAAGAGCGGTCCTAGAGCCTTAGCTGCTCGGGAGAGGAAGCGCTCTCGTGGCAACCGAAAGTCCT
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000014778_CASSETTE1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
ORF disruption upon sequence exclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.308 A=0.909 C2=1.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0218118=FH2=PD(9.4=53.8)

							
A:
NO

							
C2:
NO

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000014922





     
                   









    
Main Skipping Isoform:
NA





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr16:67230066-67230228 
HIGH PSI
HsaEX6044351
(FHOD1)
Human
(hg19)
chr16:67263969-67264131 
HIGH PSI
HsaEX6044351
(FHOD1)
Rat
(rn6)
chr19:37285587-37285749 
HIGH PSI
RnoEX0035995
(Fhod1)
Cow
(bosTau6)
chr18:34977901-34978059 
HIGH PSI
BtaEX0014626
(FHOD1)
Chicken
(galGal4)
chr11:1350088-1350244 
HIGH PSI
GgaEX7008055
(FHOD1)
Chicken
(galGal3)
chr11:1333034-1333190 
Zebrafish
(danRer10)
chr7:34340697-34340865 
HIGH PSI
DreEX6006116
(fhod1)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
TACGCATCATGCAGTTCTGCC

				
R: 
ATCTGACGTGTCGGTGGGTAA

				
Band lengths: 
244-407

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






Retrieved from "https://vastdb.crg.eu/wiki/Special:VastDB"