Special

MmuEX0019442 @ mm9

Exon Skipping

Gene
ENSMUSG00000075415 | Fnbp1
Description
formin binding protein 1 [Source:MGI Symbol;Acc:MGI:109606]
Coordinates
chr2:30895925-30911094:-
Coord C1 exon
chr2:30910948-30911094
Coord A exon
chr2:30909544-30909738
Coord C2 exon
chr2:30895925-30896034
Length
195 bp
Sequences
Splice sites
3' ss Seq
GTCCCTGGGTGTGATTGCAGGAC
3' ss Score
5.07
5' ss Seq
AAGGTACTG
5' ss Score
8.56
Exon sequences
Seq C1 exon
AAAATACAAGAGATGGAGGAGAGGCGGATTGTGCGTATTGGGGAGTCCATGAAGACGTACGCAGAGGTGGACCGGCAGGTGATACCCATCATCGGGAAGTGCCTGGACGGGATAGTGAAGGCGGCCGAGTCTATCGACCAGAAAAAC
Seq A exon
GACTCCCAGCTGGTCGTAGAAGCCTATAAGTCAGGATTCGAGCCTCCTGGAGACATTGAATTCGAAGATTACACACAGCCAATGAAACGCACAGTGTCAGACAACAGCCTTTCCAGCTCCAAAGAAGGCAAGCCTGAGCTCAGATTTGGCGGCAAGTCCAGAGGCAAGCTCTGGCCATTCATCAAGAAAAACAAG
Seq C2 exon
GGTGTCACACCAGAAGACTTCAGCAACTTCCCACCTGAGCAGAGAAGGAAAAAACTACAACAGAAAGTTGACGATCTCAATAGAGAGATACAGAAGGAGACGGACCAGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000075415_MULTIEX1-7/10=6-C2
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact





	

	
Alternative protein isoforms (Ref)





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.010 A=0.552 C2=0.956
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
NO

							
A:
NO

							
C2:
PF104814=CENP-F_N=FE(24.7=100),PF143891=Lzipper-MIP1=PU(32.5=73.0),PF154561=Uds1=PU(29.6=64.9),PF0218511=HR1=PU(24.2=40.5)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000109188





     
                   









    
Main Skipping Isoform:
ENSMUSP00000115013





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000074796, ENSMUSP00000097781, ENSMUSP00000097782, ENSMUSP00000109181, ENSMUSP00000109184, ENSMUSP00000109184f5508A, ENSMUSP00000109189, ENSMUSP00000109190, ENSMUSP00000109192, ENSMUSP00000109194
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr9:129924960-129925157 
HIGH PSI
HsaEX6063446
(FNBP1)
Human
(hg19)
chr9:132687239-132687436 
HIGH PSI
HsaEX6063446
(FNBP1)
Rat
(rn6)
chr3:9887068-9887262 
ALTERNATIVE
RnoEX0036520
(Fnbp1)
Cow
(bosTau6)
chr11:100314614-100314811 
HIGH PSI
BtaEX0014836
(FNBP1)
Chicken
(galGal4)
chr17:5756279-5756476 
HIGH PSI
GgaEX6015181
(FNBP1)
Chicken
(galGal3)
chr17:6318794-6318991 
HIGH PSI
GgaEX6015181
(FNBP1)
Zebrafish
(danRer10)
chr21:6235724-6235918 
HIGH PSI
DreEX6083064
(fnbp1b)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
GAGATGGAGGAGAGGCGGATT

				
R: 
CTCTGGTCCGTCTCCTTCTGT

				
Band lengths: 
248-443

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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