Special

MmuEX0019849 @ mm10

Exon Skipping

Gene
ENSMUSG00000034793 | G6pc3
Description
glucose 6 phosphatase, catalytic, 3 [Source:MGI Symbol;Acc:MGI:1915651]
Coordinates
chr11:102189871-102192563:+
Coord C1 exon
chr11:102189871-102190143
Coord A exon
chr11:102192035-102192141
Coord C2 exon
chr11:102192473-102192563
Length
107 bp
Sequences
Splice sites
3' ss Seq
TTGTATCTTGTCTCTTCCAGGTT
3' ss Score
12.36
5' ss Seq
CAGGTGGGA
5' ss Score
6.71
Exon sequences
Seq C1 exon
GTTCCTCGACTTGCACCCTACAACGGGCTCCAGGCTAGAGGACTCCTGATTCACCATGGAGTCCACGCTGAGCGCGGGCATCATAATGGCTGAAGCACTACAGAACCGGCTTCCCGGGCTAGAGAATATGTGGCTCTGGGTCACCTTTCTGGGCGATCCTAAGAATCTTTTTCAGTTCTGCTTCCCCGCGGCCTACTACGCCTCCCGCCGCCTGGGCATCTCCGTGCTCTGGATCACCTTCATTGCTGAGTGGCTCAACCTTGTCTTCAAGTG
Seq A exon
GTTTCTGTTTGGAGACAGGCCCTTTTGGTGGGTGCATGAATCCGGGTACTCCACCCAGACTCCAATCCAGATTCACCAGTTCCCTTCTTCTTGTGAGACTGGTCCAG
Seq C2 exon
GCAGCCCCTCCGGCCACTGCATGATCACAGGCGCAGCTCTTTGGCCTGTAATGACGGCCATTTCTTCTCAGGTGGCTTCTCGGTCCCGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000034793-'4-14,'4-13,9-14
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
ORF disruption upon sequence exclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=0.000 C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0156916=PAP2=PU(15.8=31.5)

							
A:
PF0156916=PAP2=FE(24.7=100)

							
C2:
PF0156916=PAP2=FE(20.5=100)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000064276





     
                   









    
Main Skipping Isoform:
NA





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000077995
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm9




Conservation


Human
(hg38)
chr17:44074160-44074266 
HIGH PSI
HsaEX0026720
(G6PC3)
Human
(hg19)
chr17:42151528-42151634 
HIGH PSI
HsaEX0026720
(G6PC3)
Rat
(rn6)
chr10:90136364-90136470 
HIGH PSI
RnoEX6049838
(G6pc3)
Cow
(bosTau6)
chr19:44534337-44534443 
HIGH PSI
BtaEX6089048
(G6PC3)
Chicken
(galGal4)
chrUn_JH376251:1202-1308 
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
chr12:3192297-3192403 
ALTERNATIVE
DreEX0033923
(g6pc3)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
CTGAAGCACTACAGAACCGGC

				
R: 
GCCGTCATTACAGGCCAAAGA

				
Band lengths: 
242-349

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Ribosome-engaged transcriptomes of neuronal types
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types





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