Special

MmuEX0023007 @ mm9

Exon Skipping

Gene
ENSMUSG00000055632 | Hmcn2
Description
hemicentin 2 [Source:MGI Symbol;Acc:MGI:2677838]
Coordinates
chr2:31169935-31191092:+
Coord C1 exon
chr2:31169935-31170196
Coord A exon
chr2:31189375-31189445
Coord C2 exon
chr2:31190934-31191092
Length
71 bp
Sequences
Splice sites
3' ss Seq
GCATCTCTCTCTTCCCACAGATA
3' ss Score
12.24
5' ss Seq
CAGGTGGGT
5' ss Score
8.56
Exon sequences
Seq C1 exon
ATGACGCCTGGGGCGCAGCTCCTGCCGCTGCTCGTGGCGATCTCTACAGCAGTGGCGGCGGTGGTCACGTCTGACGCGCCCACGAAGACGCTGTCCCCCGCCACAGGAGACGCCACCCTAGCCTTCGTCTTCGATGTCACCGGCTCCATGTGGGATGACCTGATGCAGGTGATCGACGGCGCCTCGCGCATTCTGGAGCGCAGCCTGAGCAGCCGCAGCCGGGTCATCGCCAACTATGCGCTGGTGCCTTTCCACGACCCAG
Seq A exon
ATATTGGCCCGGTGACCCTCACGGCAGACCCAGTGGTATTTCAGAGAGAGCTGAGAGAACTCTATGTTCAG
Seq C2 exon
GGAGGAGGTGATTGCCCAGAGATGAGTGTGGGGGCCATCAAGGCTGCCGTGGAGGTCGCCAACCCAGGCTCCTTCATCTACGTCTTCTCGGATGCCCGTGCCAAGGACTACCACAAGAAGAAGGAGCTTCTGCAGCTCCTGCAGCTGAAGCAGTCACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000055632-'0-1,'0-0,1-1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
ORF disruption upon sequence exclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.011 A=0.000 C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF135191=VWA_2=PU(28.5=55.7)

							
A:
PF135191=VWA_2=FE(13.4=100)

							
C2:
PF135191=VWA_2=FE(30.2=100)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000109160f4962A





     
                   









    
Main Skipping Isoform:
NA





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000109160
          









    
Other Skipping Isoforms:
NA
  



Associated events







Other assemblies


mm10




Conservation


Human
(hg38)
chr9:130284603-130284673 
HIGH PSI
HsaEX6063473
(HMCN2)
Human
(hg19)
chr9:133046882-133046952 
HIGH PSI
HsaEX6063473
(RP11-88G17.6)
Rat
(rn6)
chr3:10516677-10516747 
Cow
(bosTau6)
chr11:100626346-100626416 
BtaEX6046775
(HMCN2)
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
chr8_random:220235-220305 
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
ACCCTAGCCTTCGTCTTCGAT

				
R: 
TCTCTGGGCAATCACCTCCTC

				
Band lengths: 
170-241

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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