MmuEX0024667 @ mm10
Exon Skipping
Gene
ENSMUSG00000020689 | Itgb3
Description
integrin beta 3 [Source:MGI Symbol;Acc:MGI:96612]
Coordinates
chr11:104643576-104660136:+
Coord C1 exon
chr11:104643576-104644005
Coord A exon
chr11:104658723-104658945
Coord C2 exon
chr11:104660036-104660136
Length
223 bp
Sequences
Splice sites
3' ss Seq
TCTCCTGGCTCTGTTTGTAGGCC
3' ss Score
9.77
5' ss Seq
GAAGTGAGT
5' ss Score
7.97
Exon sequences
Seq C1 exon
GTGAGCTTTAGTATCGAGGCCAAGGTGCGTGGCTGCCCCCAGGAGAAGGAGCAGTCTTTCACTATCAAGCCTGTGGGCTTTAAGGACAGCCTCACCGTCCAGGTGACCTTCGACTGTGACTGTGCCTGCCAGGCCTTTGCCCAGCCTTCCAGCCCACGCTGCAACAATGGGAACGGGACTTTTGAGTGTGGGGTGTGCCGCTGTGACCAGGGCTGGCTGGGGTCCATGTGTGAGTGCTCTGAGGAGGATTACCGACCCTCTCAGCAGGAAGAGTGCAGCCCCAAGGAGGGCCAGCCCATCTGCAGCCAGCGGGGAGAGTGCCTCTGTGGCCAGTGTGTCTGCCATAGCAGCGACTTCGGCAAGATCACTGGCAAGTACTGTGAGTGCGATGACTTCTCCTGCGTCCGCTACAAAGGGGAGATGTGTTCCG
Seq A exon
GCCATGGGCAATGTAACTGTGGGGACTGCGTGTGTGACTCGGACTGGACTGGCTACTACTGCAACTGTACTACACGCACTGACACCTGCATGTCCACCAATGGGCTGCTGTGCAGCGGCCGGGGCAACTGCGAGTGCGGCAGCTGTGTGTGCGTCCAGCCAGGCTCCTATGGAGACACCTGTGAGAAGTGCCCCACCTGCCCAGATGCCTGCTCCTTTAAGAA
Seq C2 exon
GGAGTGTGTGGAGTGTAAGAAGTTCAACCGGGGAACGCTCCATGAAGAAAACACCTGCAGCCGCTACTGCCGGGATGACATCGAGCAGGTGAAAGAGCTGA
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000020689_MULTIEX2-3/3=C1-C2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.107 C2=0.462
Domain overlap (PFAM):
C1:
PF0036213=Integrin_beta=PD(9.4=27.8),PF079748=EGF_2=WD(100=25.0),PF079748=EGF_2=PU(32.3=6.9)
A:
PF079748=EGF_2=PD(64.5=26.7),PF079748=EGF_2=WD(100=42.7),PF079657=Integrin_B_tail=PU(4.7=5.3)
C2:
PF079657=Integrin_B_tail=FE(40.0=100)
Main Skipping Isoform:
ENSMUST00000021028fB2079
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGGACTTTTGAGTGTGGGGTG
R:
CGTTCCCCGGTTGAACTTCTT
Band lengths:
293-516
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types