MmuEX0026869 @ mm10
Exon Skipping
Gene
ENSMUSG00000049252 | Lrp1b
Description
low density lipoprotein-related protein 1B (deleted in tumors) [Source:MGI Symbol;Acc:MGI:2151136]
Coordinates
chr2:40611432-40629711:-
Coord C1 exon
chr2:40629607-40629711
Coord A exon
chr2:40628638-40628751
Coord C2 exon
chr2:40611432-40611508
Length
114 bp
Sequences
Splice sites
3' ss Seq
ATTTTACTGGAATTCTGCAGATG
3' ss Score
6.03
5' ss Seq
CAAGTAGGT
5' ss Score
7.33
Exon sequences
Seq C1 exon
CTGTACTAATGGGAAGATTGCCTCTAGCTGTCAGTTATGTGATGGCTACTGTTACAATGGTGGCACATGCCAGCTGGACCCTGAGACTAGTATACCTGTGTGTGT
Seq A exon
ATGCTCTGTGGGGTTTAAAAGTCAGCGCTGTGACCAGAAAGAGAACCCTTGTGATCACTACTGTCAGAATGAGGGGATTTGCACTTTAACTGCGTTTAATGAGCCGAGATGCAA
Seq C2 exon
GTGCTCCACTAATTGGTCAGGGACACAGTGTGAGAGGCCAGCCCCAAAGAGCAGCAAATCTGAGCATATCAGCACAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000049252_CASSETTE1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.178
Domain overlap (PFAM):
C1:
PF151021=TMEM154=PU(13.2=27.8)
A:
PF0000822=EGF=PU(73.7=71.8),PF151021=TMEM154=PU(23.3=51.3)
C2:
PF0000822=EGF=PD(23.7=33.3),PF151021=TMEM154=FE(30.2=100)
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTGTACTAATGGGAAGATTGCCTCT
R:
GCTCAGATTTGCTGCTCTTTGG
Band lengths:
170-284
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types