MmuEX0027279 @ mm9
Exon Skipping
Gene
ENSMUSG00000040488 | Ltbp4
Description
latent transforming growth factor beta binding protein 4 [Source:MGI Symbol;Acc:MGI:1321395]
Coordinates
chr7:28095200-28099402:-
Coord C1 exon
chr7:28099256-28099402
Coord A exon
chr7:28095540-28095806
Coord C2 exon
chr7:28095200-28095271
Length
267 bp
Sequences
Splice sites
3' ss Seq
CTTGCCTTTTGTTTCTTCAGGCA
3' ss Score
10.69
5' ss Seq
CAGGTGGGC
5' ss Score
8.07
Exon sequences
Seq C1 exon
ATGTGAATGAGTGTGAGACACTACAGGGCGTGTGTGGCTCCGCGCTGTGTGAAAATGTTGAAGGCTCCTTCCTGTGTGTCTGCCCCAATAGCCCTGAGGAATTTGATCCCATGACTGGACGCTGTGTTCCCCCACGGGCTCCTGCAG
Seq A exon
GCACGTTCCCTGGCTCCCAGCCCCAAGCACCTGCCAGCCCCAGTCTTCCAGCCAGGCCACCAGCCCCTCCCCCACCTCGAAGACCCAGCCCTCCCAGGCAGGGTCCCGTGAGCAGTGGACGTCGCGAGTGCTACTTTGATACAGCCGCTCCAGATGCGTGTGACAATATCTTGGCCCGAAACGTGACGTGGCAGGAGTGCTGCTGTACTGTGGGAGAAGGCTGGGGCAGCGGCTGCCGCATCCAACAGTGCCCGGGCACCGAGACAG
Seq C2 exon
CTGAATACCAGTCATTGTGTCCTCACGGCCGGGGCTACCTGGTGCCCAGTGGAGACCTGAGTGCCCGGAGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000040488-'38-39,'38-35,43-39
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.160 A=0.383 C2=0.032
Domain overlap (PFAM):
C1:
PF0764510=EGF_CA=WD(100=84.0)
A:
PF0068312=TB=PU(86.4=42.2)
C2:
PF0068312=TB=PD(11.4=20.0),PF0764510=EGF_CA=PU(0.1=0.0)
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGAGACACTACAGGGCGTGTG
R:
CTCCGGGCACTCAGGTCTC
Band lengths:
204-471
Functional annotations
There are 1 annotated functions for this event
PMID: 11683420
LTBP-4delta8-Cys3rd (skipping of both exons) does not bind TGF-beta and it was found to be expressed in the same tissues as the full length LTBP-4
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types
Other AS DBs: