MmuEX0028077 @ mm10
Exon Skipping
Gene
ENSMUSG00000036792 | Mbd5
Description
methyl-CpG binding domain protein 5 [Source:MGI Symbol;Acc:MGI:2138934]
Coordinates
chr2:49272041-49279783:+
Coord C1 exon
chr2:49272041-49273057
Coord A exon
chr2:49274563-49274774
Coord C2 exon
chr2:49278581-49279783
Length
212 bp
Sequences
Splice sites
3' ss Seq
TATGTTTTTCAAAACTGTAGGTG
3' ss Score
8
5' ss Seq
CAGGTACTT
5' ss Score
8.17
Exon sequences
Seq C1 exon
CTCAGATCTTTTGCAACCGCAAAATACCCCTTTACCCTTATTAACACAGATGACAGCCCCACCAGACCGTTTGCCAAGCAATCAGTCAGACAACAGCCGAGCTGATACCCTTTTAGGCAGCCCCCTGGGAAACCCTTTAGCAGGCAGTGACACTACTTTTAACCCCCTGCTCCTCCCAGCTGTCACTGGGGCCTCAGGATTAATGGCCTTGAATCCCCAGCTGTTGGGGGGTGTCCTGAACTCGGCATCGGCCAACACCGCTATTCATCCAGAGGTTTCCATAGCAACCTCCTCCCAGGCAACCACTACCACAACCACTACATCATCAGCAGTGGCAGCACTGACTGTCTCAACACTTGGTGGGACAGCAGTGGTGTCAATGGCAGAAACATTGCTGAATATATCTAATAATGCTGGGAATCCACCTGGTCCAGCTAAACTCAACAGTAACTCTATGGTGCCACAGCTACTTAACCCTCTACTGGGGACAGGTCTGCTTG
Seq A exon
GTGATATATCATCCATAAACAATTCATTGAATAACCATCAACTGACTCATCTACAGTCGCTACTAAACAGCAATCAGATGTTTCCTCCAAATCAGCAGCCGCAGCAACACCTTCTCCAGGGACACCAGAATCTCCAGGCCTTCCAAGGACAACCCACAGTCCCTTGCCCAGCTAACAATAACCCCATGGCTTGTCTGTTTCAGAACTTCCAG
Seq C2 exon
GTGAGGATGCAAGGAGATGCAGCTCTTCTAAATAAAAGAATAAGCACTCAGCCTGGGCTCACAACACTTCCTGAAAACCCAAACCTTGCACTTCCACATTTCCAAGATACACCCTGTGAGCTGCAGCCAAGGATTGACCTTGGTCAGCCTATGAAGGACGGCCTCGTTATGGGTGGCCAAGGAGATGCCTCCGTAGACGCCATTTACAAAGCAGTTGTGGATGCAGCCAGCAAAGGAATGCAGGTTGTCATCACCACTGCTGTCAACAGCACGACTCAAATCAGCCCTATCCCAGCCCTGAGCGCCATGAGTGCCTTCACTGCCTCCATTGGTGACCCATTAAATCTGTCCAGTGCTGTGAGCGCTGTCATCCACGGGCGGAACATGGGAGGAGTGGATCATGATGGCAGGCTGAGGAATGCGAGAGGGGCACGGCTACCCAAGAACATAGACCATGGGAAGAACTCCAGCGAAGGAGACGGGTTTGAGTGTTTCAAGTC
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000036792-'59-52,'59-51,60-52
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
Show structural model
Features
Disorder rate (Iupred):
C1=0.309 A=0.662 C2=0.482
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
PF0085512=PWWP=PU(46.3=9.5)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCCATAGCAACCTCCTCCCAG
R:
CAGGAAGTGTTGTGAGCCCAG
Band lengths:
296-508
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types