MmuEX0041256 @ mm9
Exon Skipping
Gene
ENSMUSG00000064329 | Scn1a
Description
sodium channel, voltage-gated, type I, alpha [Source:MGI Symbol;Acc:MGI:98246]
Coordinates
chr2:66126931-66134932:-
Coord C1 exon
chr2:66134810-66134932
Coord A exon
chr2:66131889-66131952
Coord C2 exon
chr2:66126931-66127212
Length
64 bp
Sequences
Splice sites
3' ss Seq
TATATTTCTATTTTATATAGGAT
3' ss Score
8.01
5' ss Seq
TGGGTACTG
5' ss Score
2.97
Exon sequences
Seq C1 exon
GTTTCATTGGTCAGTTTAACAGCAAATGCCTTGGGTTACTCTGAACTCGGGGCCATCAAATCCCTAAGGACACTAAGAGCTCTGAGACCCCTAAGAGCCTTATCACGATTTGAAGGGATGAGG
Seq A exon
GATAATCTTGCTCCAACTTGGATGGGGTGGAGCGGTGGTTCCTCCCCTCAGCCCTTTATTATGG
Seq C2 exon
GTGGTTGTGAATGCCCTGTTAGGAGCAATTCCATCCATCATGAATGTGCTTCTGGTTTGCCTTATATTCTGGCTAATTTTCAGCATCATGGGCGTAAATTTGTTTGCTGGCAAATTCTACCACTGTGTTAACACCACAACTGGTGACATATTTGAGATCAGCGAAGTCAATAATCATTCTGATTGCCTAAAACTAATAGAAAGAAATGAGACCGCCCGGTGGAAAAATGTGAAAGTAAACTTTGATAATGTAGGATTTGGGTATCTTTCTTTGCTTCAAGTT
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000064329-'26-27,'26-26,27-27
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0052026=Ion_trans=FE(17.5=100)
A:
PF0052026=Ion_trans=PD(7.9=31.8)
C2:
PF0052026=Ion_trans=FE(40.6=100)
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CGGGGCCATCAAATCCCTAAG
R:
AGGCAAACCAGAAGCACATTCA
Band lengths:
138-202
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types
Other AS DBs: