Special

MmuEX0041312 @ mm9

Exon Skipping

Gene
ENSMUSG00000020877 | Scrn2
Description
secernin 2 [Source:MGI Symbol;Acc:MGI:1343092]
Coordinates
chr11:96892194-96894284:+
Coord C1 exon
chr11:96892194-96892375
Coord A exon
chr11:96893403-96893602
Coord C2 exon
chr11:96894069-96894284
Length
200 bp
Sequences
Splice sites
3' ss Seq
GTACTCTGATTTTCTATCAGGCT
3' ss Score
7.5
5' ss Seq
AGGGTAGGA
5' ss Score
6.45
Exon sequences
Seq C1 exon
TGTACCTATATCGAGGTGGAACAGGTGGGGAAGACACACGCTGTGATTCTGAGCCGCCCCTCTTGGCTGTGGGGAGCTGAGATGGGGGCCAACGAGCTTGGTGTCTGCATTGGAAACGAAGCAGTGTGGACCAAAGAGCCTGTGGGGCAGGGGGAAGCCCTGCTGGGTATGGACCTGCTCAG
Seq A exon
GCTGGCTTTGGAACGGAGCAGCACTGCCCAGGAGGCTGTTCACGTGATTGCAGGCTTGCTGGACCGCTATGGGCAGGGAGGCAGCTGCCGGGAGGATCCAGAGCCGTTCTGCTATCACAACACCTTTTTACTGGCTGATCGGACAGAGGCGTGGGTGCTGGAGACAGCTGGGAGCCTGTGGGCTGCTCAGCGGATCCAGG
Seq C2 exon
GAGGTGCCCGGAATATTTCCAACCAGCTGAGCATTGGTACAGACATCTCAGCTGAACACCCGGAGCTCCGCAGCCATGCCAAGGCTCAGGGTTGGTGGACTGGGCAGGGCCTCTTTGACTTTGCGGAGGTCTTCTCCCTGACCCAGCAGCCTGTGCGCATGGAGGCTGCCAAGGCCCGCTTCCGGGCAGGGTGTGAGATGCTGCAGCGGCATCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000020877-'2-4,'2-3,6-4
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
ORF disruption upon sequence exclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=0.000 C2=0.027
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0357710=Peptidase_C69=PU(21.0=60.7)

							
A:
PF0357710=Peptidase_C69=FE(38.1=100)

							
C2:
PF0357710=Peptidase_C69=PD(40.3=97.3)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000021249





     
                   









    
Main Skipping Isoform:
NA





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000116606
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr17:47839444-47839643 
HIGH PSI
HsaEX0056645
(SCRN2)
Human
(hg19)
chr17:45916810-45917009 
HIGH PSI
HsaEX0056645
(SCRN2)
Rat
(rn6)
chr10:84969160-84969359 
HIGH PSI
RnoEX0078698
(Scrn2)
Cow
(bosTau6)
chr19:39238652-39238851 
ALTERNATIVE
BtaEX0031618
(SCRN2)
Chicken
(galGal4)
chr27:3894943-3895142 
HIGH PSI
GgaEX7011010
(SCRN2)
Chicken
(galGal3)
chr7:18111213-18111412 
Zebrafish
(danRer10)
chr9:2518463-2518662 
HIGH PSI
DreEX6034749
(scrn3)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
GAACAGGTGGGGAAGACACAC

				
R: 
ACCTCCGCAAAGTCAAAGAGG

				
Band lengths: 
294-494

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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