Special

MmuEX0045155 @ mm9

Exon Skipping

Gene
ENSMUSG00000026811 | St6galnac6
Description
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 [Source:MGI Symbol;Acc:MGI:1355316]
Coordinates
chr2:32455229-32467923:+
Coord C1 exon
chr2:32455229-32455356
Coord A exon
chr2:32464746-32464836
Coord C2 exon
chr2:32467744-32467923
Length
91 bp
Sequences
Splice sites
3' ss Seq
CCCTTTCTGGTGGCTTGCAGGTG
3' ss Score
10.81
5' ss Seq
AAAGTAAGT
5' ss Score
9.72
Exon sequences
Seq C1 exon
ACTTCCTCCAAGCACACAAAGATGCCCACTGACAGGTCTGGCTGTTGGCACAGCGTCTACTGAAGACTCCCATGATGAAACTCAGGGGCCCCCTCCTTGGACACTGTGGGTCCGGTACCTGCTGGAAG
Seq A exon
GTGTGACCCCACAACCCTGCCCCCCGGGCCACCTGCCGGACGCTGGCCTCTACCCTTCAGCAGACGCCGGAGAGAGATGAGTAGCAACAAA
Seq C2 exon
GAGCAGCGGTCAGCAGTGTTTGTGATCCTCTTTGCCCTCATCACCATCCTCATCCTCTACAGCTCCAACAGTGCCAACGAGGTCTTCCACTACGGCTCCCTGCGGGGCCGCACGCGTCGGCCAGTCAACCTCAAGAAGTGGAGTTTCTCCAGCGCCTACTTCCCTATCCTCGGCAACAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000026811_MULTIEX1-2/3=C1-3
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact





	

	
ORF disruption upon sequence exclusion





Show structural model

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=0.509 C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
NO

							
A:
NO

							
C2:
PF0077713=Glyco_transf_29=PU(16.1=73.3)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000108915





     
                   









    
Main Skipping Isoform:
ENSMUSP00000092655





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000071983, ENSMUSP00000080555, ENSMUSP00000092654, ENSMUSP00000108914, ENSMUSP00000114934, ENSMUSP00000118893, ENSMUSP00000121833
          









    
Other Skipping Isoforms:
ENSMUSP00000115430
  



Associated events







Other assemblies


mm10




Conservation


Human
(hg38)
No conservation detected
Human
(hg19)
chr9:130658521-130658611 
HIGH PSI
HsaEX6063153
(ST6GALNAC6)
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
chr11:98577315-98577402 
HIGH PSI
BtaEX6046313
(ST6GALNAC6)
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
GTTGGCACAGCGTCTACTGAA

				
R: 
AAGACCTCGTTGGCACTGTTG

				
Band lengths: 
171-262

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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