Special

MmuEX0050346 @ mm10

Exon Skipping

Gene
Description
ubiquitin protein ligase E3 component n-recognin 3 [Source:MGI Symbol;Acc:MGI:1861100]
Coordinates
chr2:69993676-70000543:+
Coord C1 exon
chr2:69993676-69993812
Coord A exon
chr2:69999085-69999218
Coord C2 exon
chr2:70000458-70000543
Length
134 bp
Sequences
Splice sites
3' ss Seq
CCATTAATTTTTTTCTACAGATT
3' ss Score
10.69
5' ss Seq
CTGGTAGGT
5' ss Score
8.37
Exon sequences
Seq C1 exon
TCAGAAACCAACTTAAGTAAAGAAATGGAATCTGTAATGAAAGATATAAAAAATACCACTCAGAAGAAATACAGAGACTATAGCAAGACCCCAGGCTCACCAGACAACGAGTTTCTCTTTATGTACTCTGTTGCTAG
Seq A exon
ATTAGGCAACAGAAGATTTGTGAAAACAAAATATATTGATCTCATTTATATTCCCTTGATGAAGGAACACATGCTGGTCTCCGCGCTCGCTTTCTGTCCACTAATATGAAATCCTTGTCCCTGCTTCCTTGCTG
Seq C2 exon
AACCAATCTGGAGCTGGAACTGATTCATAGAGGAGGCAGTCTCTGCTCCGGTGGTCCAAGCACAGCGGGGAAAAGATCTTGTCTGA
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000044308_CASSETTE5
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact

ORF disruption upon sequence inclusion

No structure available
Features
Disorder rate (Iupred):
  C1=0.344 A=0.000 C2=0.000
Domain overlap (PFAM):

C1:
NO
A:
NA
C2:
NO


Main Inclusion Isoform:
NA


Main Skipping Isoform:


Other Inclusion Isoforms:
NA


Other Skipping Isoforms:
Other assemblies
Conservation
Chicken
(galGal4)
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TACCACTCAGAAGAAATACAGAGACT
R:
TCAGACAAGATCTTTTCCCCGC
Band lengths:
170-304
Functional annotations
There are 0 annotated functions for this event


GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]


SPECIAL DATASETS

  • Pre-implantation embryo development
  • Ribosome-engaged transcriptomes of neuronal types
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types