MmuEX1015752 @ mm10
Exon Skipping
Gene
ENSMUSG00000007670 | Khsrp
Description
KH-type splicing regulatory protein [Source:MGI Symbol;Acc:MGI:1336214]
Coordinates
chr17:57025880-57027098:-
Coord C1 exon
chr17:57027049-57027098
Coord A exon
chr17:57026900-57026914
Coord C2 exon
chr17:57025880-57025937
Length
15 bp
Sequences
Splice sites
3' ss Seq
TTTTTTTTCTTTCTGCTCAGTTA
3' ss Score
8.99
5' ss Seq
GTGGTGAGC
5' ss Score
6.64
Exon sequences
Seq C1 exon
GACCTCAATGACAGAAGAGTATAGGGTTCCGGATGGCATGGTGGGCTTGA
Seq A exon
TTATTGGCAGAGGTG
Seq C2 exon
ATAGTGGTGGCCTCCCTGAGCGCAGCGTGTCTCTGACTGGAGCACCTGAGTCTGTCCA
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000007670-MICROEX1
Average complexity
MIC-S
Mappability confidence:
NA
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.833 A=0.800 C2=0.950
Domain overlap (PFAM):
C1:
PF0001324=KH_1=PU(20.6=72.2)
A:
PF0001324=KH_1=FE(38.1=100)
C2:
PF0001324=KH_1=FE(30.2=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Rat
(rn6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACCTCAATGACAGAAGAGTATAGGGT
R:
AGACTCAGGTGCTCCAGTCAG
Band lengths:
102-117
Functional annotations
There are 1 annotated functions for this event
PMID: 19770516
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: coimmunoprecipitation, mutation analysis. ELM ID: ELMI002009; ELM sequence: VQISPD; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types