MmuEX6002861 @ mm9
Exon Skipping
Gene
ENSMUSG00000029757 | Dync1i1
Description
dynein cytoplasmic 1 intermediate chain 1 [Source:MGI Symbol;Acc:MGI:107743]
Coordinates
chr6:5734439-5855194:+
Coord C1 exon
chr6:5734439-5734498
Coord A exon
chr6:5750775-5750890
Coord C2 exon
chr6:5855105-5855194
Length
116 bp
Sequences
Splice sites
3' ss Seq
TTGCCCTCTGCTACTTACAGGAG
3' ss Score
7.96
5' ss Seq
AAGGTAAAC
5' ss Score
8.14
Exon sequences
Seq C1 exon
GACCCTGCAGTGGGACACAGACCCCTCAGTGCTCCAGCTGCAGTCAGACTCAGAACTTGG
Seq A exon
GAGACGACTGCACAAGCTGGGCGTGTCAAAGGTGACCCAGGTGGATTTCCTGCCTAGGGAAGTAGTATCCTACTCCAAGGAGACACAGACTCCTCTTGCAACACATCAGTCTGAAG
Seq C2 exon
AGGATGAGGAAGATGAGGAGATGGTAGAACCCAAAATTGGTCATGATTCTGAACTGGAGAATCAAGAAAAAAAGCAGGAGACAAAGGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000029757-'6-8,'6-7,7-8=AN
Average complexity
A_C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.937 A=0.550 C2=1.000
Domain overlap (PFAM):
C1:
PF115403=Dynein_IC2=PU(0.1=0.0)
A:
PF115403=Dynein_IC2=WD(100=82.5)
C2:
NO
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGGACACAGACCCCTCAGTG
R:
CTTCCTTTGTCTCCTGCTTTTT
Band lengths:
139-255
Functional annotations
There are 1 annotated functions for this event
PMID: 11148209
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: circular dichroism, competition binding, mutation analysis, nuclear magnetic resonance, pull down. ELM ID: ELMI000092; ELM sequence: YSKETQT; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
Other AS DBs: