RnoEX6012652 @ rn6
Exon Skipping
Gene
ENSRNOG00000009700 | Dync1i1
Description
dynein cytoplasmic 1 intermediate chain 1 [Source:RGD Symbol;Acc:2512]
Coordinates
chr4:30868775-30999822:+
Coord C1 exon
chr4:30868775-30868834
Coord A exon
chr4:30891941-30892056
Coord C2 exon
chr4:30999733-30999822
Length
116 bp
Sequences
Splice sites
3' ss Seq
TTGCCCTCTGCTGCTTACAGGAG
3' ss Score
8.2
5' ss Seq
AAGGTAAGC
5' ss Score
10.22
Exon sequences
Seq C1 exon
GACCCTGCAGTGGGACACAGACCCCTCAGTGCTCCAGCTGCAGTCAGACTCAGAACTTGG
Seq A exon
GAGAAGACTGAACAAGCTGGGCGTGTCAAAGGTTACCCAGGTGGATTTCCTGCCTAGGGAGGTGGTATCCTACTCCAAGGAGACACAGACTCCTCTTGCAACTCATCAGTCAGAAG
Seq C2 exon
AGGATGAGGAAGATGAGGAGATGGTTGAGCCCAAAGTTGGTCATGATTCTGAACTGGAAAATCAAGACAAAAAGCAGGAGACAAAGGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSRNOG00000009700-'10-17,'10-13,12-17=AN
Average complexity
A_C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.857 A=0.350 C2=1.000
Domain overlap (PFAM):
C1:
PF115403=Dynein_IC2=PU(0.1=0.0)
A:
PF115403=Dynein_IC2=WD(100=82.5)
C2:
NO
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGGGACACAGACCCCTCAGT
R:
TCCTTTGTCTCCTGCTTTTTGTCT
Band lengths:
138-254
Functional annotations
There are 1 annotated functions for this event
PMID: 11148209
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: circular dichroism, competition binding, mutation analysis, nuclear magnetic resonance, pull down. ELM ID: ELMI000092; ELM sequence: YSKETQT; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]