HsaEX6009106 @ hg19
Exon Skipping
Gene
ENSG00000158560 | DYNC1I1
Description
dynein, cytoplasmic 1, intermediate chain 1 [Source:HGNC Symbol;Acc:2963]
Coordinates
chr7:95457369-95606913:+
Coord C1 exon
chr7:95457369-95457428
Coord A exon
chr7:95499195-95499310
Coord C2 exon
chr7:95606824-95606913
Length
116 bp
Sequences
Splice sites
3' ss Seq
TTATTCTTTGTTACTTACAGAAG
3' ss Score
8.5
5' ss Seq
AAGGTAAAC
5' ss Score
8.14
Exon sequences
Seq C1 exon
GACCCTGCAGTGGGACACAGACCCCTCAGTGCTCCAGCTGCAGTCAGACTCAGAACTTGG
Seq A exon
AAGAAGACTGCATAAACTGGGCGTGTCAAAGGTCACCCAAGTGGATTTCCTGCCAAGGGAAGTAGTGTCCTACTCAAAGGAGACCCAGACTCCTCTTGCCACGCATCAGTCTGAAG
Seq C2 exon
AGGATGAGGAAGATGAGGAAATGGTGGAATCTAAAGTTGGCCAGGACTCAGAACTGGAAAATCAGGACAAAAAACAGGAAGTGAAGGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000158560-'9-12,'9-11,12-12=AN
Average complexity
A_C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.930 A=0.500 C2=1.000
Domain overlap (PFAM):
C1:
PF115403=Dynein_IC2=PU(0.1=0.0)
A:
PF115403=Dynein_IC2=WD(100=82.5)
C2:
NO
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGGACACAGACCCCTCAGTG
R:
TTTTTGTCCTGATTTTCCAGTTCTGA
Band lengths:
122-238
Functional annotations
There are 1 annotated functions for this event
PMID: 11148209
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: circular dichroism, competition binding, mutation analysis, nuclear magnetic resonance, pull down. ELM ID: ELMI000092; ELM sequence: YSKETQT; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)