Special

MmuEX6007315 @ mm10

Exon Skipping

Gene
Description
alpha-2-macroglobulin like 1 [Source:MGI Symbol;Acc:MGI:3039594]
Coordinates
chr6:128546249-128548684:-
Coord C1 exon
chr6:128548604-128548684
Coord A exon
chr6:128547157-128547322
Coord C2 exon
chr6:128546249-128546460
Length
166 bp
Sequences
Splice sites
3' ss Seq
TTTCCCCCAACCCCAACTAGTTT
3' ss Score
4.74
5' ss Seq
CAAGTAAGT
5' ss Score
10.08
Exon sequences
Seq C1 exon
GGCCGTGAGGGTGACCAGGAAGATATTGCGCTCACTGCGTACGTCGTCGGGGTGTTCCTTGAAGTTGGACTCAATGCCAGC
Seq A exon
TTTCCTGCCCTCCGCAATGGTCTCTATTGCCTGGAAGAGGCATTTTCGAATGGTGTCACCAATGGCTACACGCAAGCTATTCTGGCTTATGTATTTGCATTAGCTGGGAAAGAACAGCAAGCGAAATCCTTACTCTCAATCCTGGACAAATCTGCTACAAAAACAA
Seq C2 exon
ATAATATGATATACTGGGAGAGAGATGAGAAACCCGAGACAGACAACTCTCCATCATTCATTCCTTCGGCACTTTCTGGTGAGACAGAGAAGACGTGCTATGTGCTGCTGGCTGTCCTTTCCCAGGACACTCAGGACCTTGATTATGCCAGCAAGATTGTGCAGTGGCTTGCCCAGCGGATGAACTCCCATGGAGGCTTCTCTGCCATGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000047228-'49-42,'49-41,52-42=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact

ORF disruption upon sequence exclusion

No structure available
Features
Disorder rate (Iupred):
  C1=0.111 A=0.000 C2=0.197
Domain overlap (PFAM):

C1:
PF076789=A2M_comp=FE(10.5=100)
A:
PF076789=A2M_comp=FE(22.2=100)
C2:
PF076789=A2M_comp=FE(28.2=100)


Main Inclusion Isoform:


Main Skipping Isoform:
NA


Other Inclusion Isoforms:
NA


Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
HIGH PSI
([1])
Chicken
(galGal3)
HIGH PSI
([2])
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTGACCAGGAAGATATTGCGCT
R:
CAAGCCACTGCACAATCTTGC
Band lengths:
242-408
Functional annotations
There are 0 annotated functions for this event


GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]


SPECIAL DATASETS

  • Ribosome-engaged transcriptomes of neuronal types
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types