MmuEX6007454 @ mm10
Exon Skipping
Gene
ENSMUSG00000030201 | Lrp6
Description
low density lipoprotein receptor-related protein 6 [Source:MGI Symbol;Acc:MGI:1298218]
Coordinates
chr6:134506196-134511287:-
Coord C1 exon
chr6:134511156-134511287
Coord A exon
chr6:134507286-134507682
Coord C2 exon
chr6:134506196-134506367
Length
397 bp
Sequences
Splice sites
3' ss Seq
ATTTTTCTTTGTTGATTTAGGTG
3' ss Score
10.32
5' ss Seq
TGGGTAAGA
5' ss Score
8.91
Exon sequences
Seq C1 exon
CTACAAATCCATGTGGAATTGATAATGGTGGTTGTTCCCATTTGTGTTTGATGTCTCCAGTCAAGCCTTTTTATCAGTGTGCTTGCCCAACTGGGGTCAAGCTGCTGGAGAATGGAAAGACCTGCAAAGATG
Seq A exon
GTGCCACTGAACTATTGCTGTTAGCCCGACGGACAGACTTGAGGCGAATTTCTTTGGATACACCCGATTTTACTGACATTGTTCTGCAGTTAGAAGATATCCGGCATGCCATTGCCATAGACTATGACCCTGTAGAAGGCTACATATACTGGACGGATGACGAAGTGAGGGCTATCCGTCGCTCCTTCATAGATGGATCTGGCAGTCAGTTTGTGGTCACGGCCCAGATTGCTCATCCTGATGGTATTGCTGTTGACTGGGTTGCAAGGAACCTGTACTGGACAGACACTGGCACGGATCGTATAGAAGTGACAAGGCTCAATGGGACCATGAGGAAGATCTTGATTTCAGAGGACTTAGAGGAGCCCCGGGCTATCGTGTTAGATCCCATGGTTGG
Seq C2 exon
GTACATGTATTGGACAGACTGGGGAGAAATCCCAAAAATAGAGCGAGCTGCTCTGGACGGATCTGACCGAGTAGTTCTTGTCAACACTTCCCTTGGTTGGCCAAACGGCTTAGCCCTGGATTATGATGAAGGCACAATATACTGGGGAGATGCCAAAACAGACAAAATTGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000030201-'13-10,'13-9,15-10
Average complexity
S
Mappability confidence:
89%=80=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.047 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF146701=FXa_inhibition=WD(100=84.4)
A:
PF0005812=Ldl_recept_b=WD(100=30.8),PF0005812=Ldl_recept_b=WD(100=30.8),PF0005812=Ldl_recept_b=PU(0.1=0.0)
C2:
PF0005812=Ldl_recept_b=WD(100=72.4),PF0005812=Ldl_recept_b=PU(33.3=22.4)
Main Skipping Isoform:
ENSMUST00000032322fB2271
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCCATGTGGAATTGATAATGGTGGT
R:
AATTTTGTCTGTTTTGGCATCTCCC
Band lengths:
294-691
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types