RnoEX6015361 @ rn6
Exon Skipping
Gene
ENSRNOG00000006338 | Lrp6
Description
LDL receptor related protein 6 [Source:RGD Symbol;Acc:1304749]
Coordinates
chr4:168260038-168264774:-
Coord C1 exon
chr4:168264643-168264774
Coord A exon
chr4:168261112-168261508
Coord C2 exon
chr4:168260038-168260209
Length
397 bp
Sequences
Splice sites
3' ss Seq
CTTTTTCTTTGTTGTTTTAGGTG
3' ss Score
12.59
5' ss Seq
TGGGTAAGA
5' ss Score
8.91
Exon sequences
Seq C1 exon
CTACAAATCCATGTGGAATTGATAATGGTGGTTGTTCCCATTTGTGTTTGATGTCTCCAGTCAAGCCTTTTTATCAGTGTGCTTGTCCAACTGGGGTCAAGCTTCTGGAGAGTGGAAAAACCTGCAAAGATG
Seq A exon
GTGCCACTGAACTATTGCTGTTAGCCCGACGGACAGACTTGAGGCGCATCTCTTTGGATACACCAGATTTCACCGACATTGTCCTACAGTTAGAAGACATCCGACATGCCATTGCCATAGACTACGACCCCGTGGAAGGCTACGTCTACTGGACGGACGATGAAGTACGGGCCATCCGTCGCTCCTTCATTGATGGATCTGGCAGTCAGTTTGTGGTCACGGCCCAGATTGCCCATCCTGATGGTATTGCTGTTGACTGGGTGGCAAGAAACCTGTACTGGACAGACACTGGCACTGATCGGATAGAAGTGACAAGGCTCAATGGGACCATGAGGAAGATCCTGATTTCAGAGGACTTAGAGGAGCCCCGGGCTATTGTGTTAGATCCCATGGCTGG
Seq C2 exon
GTACATGTACTGGACGGACTGGGGAGAAATCCCAAAAATCGAGCGAGCTGCTCTGGACGGATCTGACCGAGTAGTTCTTGTTAACACTTCCCTTGGTTGGCCAAATGGCTTAGCCCTGGATTATGATGAAGGCACAATATACTGGGGAGATGCCAAAACAGACAAAATTGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSRNOG00000006338-'6-11,'6-10,8-11=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.044 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF146701=FXa_inhibition=WD(100=84.4)
A:
PF0005812=Ldl_recept_b=WD(100=30.8),PF0005812=Ldl_recept_b=WD(100=30.8),PF0005812=Ldl_recept_b=PU(0.1=0.0)
C2:
PF0005812=Ldl_recept_b=WD(100=72.4),PF0005812=Ldl_recept_b=PU(33.3=22.4)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Mouse
(mm9)
No conservation detected
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCCATGTGGAATTGATAATGGTGGT
R:
AATTTTGTCTGTTTTGGCATCTCCC
Band lengths:
294-691
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]