Special

MmuEX6035358 @ mm9

Exon Skipping

Gene
ENSMUSG00000025044 | Msr1
Description
macrophage scavenger receptor 1 [Source:MGI Symbol;Acc:MGI:98257]
Coordinates
chr8:40705232-40716748:-
Coord C1 exon
chr8:40716635-40716748
Coord A exon
chr8:40709280-40709689
Coord C2 exon
chr8:40705232-40705418
Length
410 bp
Sequences
Splice sites
3' ss Seq
TTTTTTATTCAAATATTCAGCTC
3' ss Score
5.35
5' ss Seq
GAGGTAAGC
5' ss Score
9.85
Exon sequences
Seq C1 exon
GCACTAAAAATGGCCCCTCCCTTCAGGAGAAGTTGAAGTCCTTCAAGGCTGCCCTCATTGCTCTCTACCTCCTTGTGTTTGCAGTACTAATACCTGTTGTTGGAATAGTAACAG
Seq A exon
CTCAGCTTTTGAATTGGGAAATGAAGAACTGCTTAGTTTGTTCACTTAACACAAGTGACACATCTCAAGGTCCTATGGAAAAAGAAAATACCAGTAAAGTGGAAATGAGATTTACAATTATCATGGAACACATGAAGGACATGGAGGAGAGAATCGAAAGCATTTCAAACTCAAAAGCCGACCTTATAGACACGGAACGCTTCCAGAATTTCAGCATGGCAACTGACCAAAGACTTAATGATATTCTTCTGCAGTTAAATTCCTTGATTTCGTCAGTCCAGGAACATGGGAATTCACTGGATGCAATCTCCAAGTCCTTGCAGAGTCTGAATATGACACTGCTTGATGTTCAACTCCATACAGAAACACTGAATGTCAGAGTCCGTGAATCTACAGCAAAGCAACAGGAG
Seq C2 exon
GACATCAGTAAATTGGAGGAACGTGTGTACAAAGTATCAGCAGAAGTCCAGTCTGTGAAAGAAGAACAAGCGCACGTGGAACAGGAAGTAAAACAGGAAGTGAGAGTATTGAACAACATCACCAACGACCTCAGACTGAAGGACTGGGAACACTCACAGACACTGAAAAACATCACCTTCATTCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000025044-'3-4,'3-3,4-4=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact





	

	
ORF disruption upon sequence exclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.122 A=0.152 C2=0.545
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
NO

							
A:
PF045827=Reo_sigmaC=PU(73.2=95.6),PF131661=AAA_13=PU(70.0=97.1),PF035238=Macscav_rec=WD(100=35.8)

							
C2:
PF045827=Reo_sigmaC=PD(25.7=73.0),PF131661=AAA_13=PD(28.9=87.3),PF0139113=Collagen=PU(3.6=3.2)

						

					

				








    
Main Inclusion Isoform:
ENSMUSP00000026021





     
                   









    
Main Skipping Isoform:
NA





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000026021f6048A, ENSMUSP00000106114, ENSMUSP00000132535
          









    
Other Skipping Isoforms:
NA
  



Associated events






Conservation


Human
(hg38)
chr8:16168458-16168870 
ALTERNATIVE
HsaEX0040331
(MSR1)
Human
(hg19)
chr8:16025967-16026379 
HIGH PSI
HsaEX0040331
(MSR1)
Rat
(rn6)
chr16:56874746-56875155 
HIGH PSI
RnoEX6055684
(Msr1)
Cow
(bosTau6)
chr27:19992181-19992590 
HIGH PSI
BtaEX6106760
(MSR1)
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
GCACTAAAAATGGCCCCTCCC

				
R: 
GAAGGTGATGTTTTTCAGTGTCTGTG

				
Band lengths: 
294-704

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]










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