MmuEX6042226 @ mm10
Exon Skipping
Gene
ENSMUSG00000022041 | Chrna2
Description
cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal) [Source:MGI Symbol;Acc:MGI:87886]
Coordinates
chr14:66142144-66143965:+
Coord C1 exon
chr14:66142144-66142286
Coord A exon
chr14:66143357-66143508
Coord C2 exon
chr14:66143921-66143965
Length
152 bp
Sequences
Splice sites
3' ss Seq
TTTCTGTCCCTATCTCACAGTGT
3' ss Score
10.44
5' ss Seq
GTGGTGGGC
5' ss Score
2.56
Exon sequences
Seq C1 exon
CTGCAGAGAGACAGGGCCTTGAAGAAGCCAGCTCCTTGTAGTCCAACAGAAACCAGGACCCTCTGAAGCCATGGCCCCCTCCCATCCTGCTTTCCAGTTCTGGATACATCTTTATCTCTGGTGTCTGCTTCTGATGCCAGCAG
Seq A exon
TGTTGGCCCAGCAAGGCTCGCACACCCATGCCGAGGACCGCCTGTTCAAACACCTCTTTGGAGGCTACAATCGCTGGGCACGGCCAGTGCCCAACACTTCCGATGTGGTCATCGTGCGCTTTGGACTATCCATTGCACAGCTCATAGATGTG
Seq C2 exon
GATGAGAAGAATCAAATGATGACCACCAATGTCTGGCTAAAGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000022041-'1-7,'1-3,4-7=AN
Average complexity
A_S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
PF0293118=Neur_chan_LBD=PU(18.8=76.5)
C2:
PF0293118=Neur_chan_LBD=FE(6.8=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTGCAGAGAGACAGGGCCTT
R:
CCAGACATTGGTGGTCATCAT
Band lengths:
179-331
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types