MmuEX6072203 @ mm10
Exon Skipping
Gene
ENSMUSG00000027950 | Chrnb2
Description
cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal) [Source:MGI Symbol;Acc:MGI:87891]
Coordinates
chr3:89763010-89764608:-
Coord C1 exon
chr3:89764343-89764608
Coord A exon
chr3:89763220-89763365
Coord C2 exon
chr3:89763010-89763054
Length
146 bp
Sequences
Splice sites
3' ss Seq
TCCTGCCTTCCCTTGCCCAGGGG
3' ss Score
8.64
5' ss Seq
GTGGTAAGT
5' ss Score
10.36
Exon sequences
Seq C1 exon
ACTTGTGTTCCCTAGAAGAGCAGCCGGGACCGGCAAGAAGCCGGGACCTCCCCCTCGTTCCAGGAACTGCCGCGCAGTGGGCACTTCAGCCCTGGAGGCCGCGAGCCCCACCCGGGTGAAGGCGGCTGCGCGGCTTCAGCACCACGGACAGCGCTCCGTCCGCAGCCCTTGTGTCAGCGAGGCTCCGCGCTATGCAGGCGGCATGGCCCGGTGCTCCAACTCTATGGCGCTGCTGTTCAGCTTTGGCCTCCTTTGGCTGTGTTCAG
Seq A exon
GGGTTTTGGGTACTGACACAGAGGAGCGGCTGGTGGAGCATCTCTTGGATCCTTCCCGCTATAACAAGCTGATCCGTCCAGCTACTAATGGCTCTGAGCTGGTGACTGTACAGCTCATGGTATCATTGGCACAGCTCATCAGTGTG
Seq C2 exon
CACGAGCGGGAGCAGATCATGACCACCAACGTCTGGCTGACCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000027950-'3-4,'3-2,6-4=AN
Average complexity
A_S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
PF0293118=Neur_chan_LBD=PU(19.9=83.7)
C2:
PF0293118=Neur_chan_LBD=FE(6.8=100)
Main Skipping Isoform:
ENSMUST00000029562fB1009
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTCCCCCTCGTTCCAGGAAC
R:
ACGTTGGTGGTCATGATCTGC
Band lengths:
251-397
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types