Special

MmuEX6097884 @ mm10

Exon Skipping

Gene
Description
mechanistic target of rapamycin (serine/threonine kinase) [Source:MGI Symbol;Acc:MGI:1928394]
Coordinates
chr4:148549791-148551024:+
Coord C1 exon
chr4:148549791-148549865
Coord A exon
chr4:148550088-148550223
Coord C2 exon
chr4:148550959-148551024
Length
136 bp
Sequences
Splice sites
3' ss Seq
GTTTTCTGACCTTTGTGCAGGTT
3' ss Score
8.33
5' ss Seq
ACAGTAAGC
5' ss Score
5.94
Exon sequences
Seq C1 exon
GTCGCTATGACCAGAGAGAAATTTCCAGAAAAGATTCCATTTAGACTAACAAGAATGTTGACCAATGCTATGGAG
Seq A exon
GTTACGGGTCTGGATGGCAACTACAGAACCACATGCCACACCGTGATGGAAGTGCTCCGGGAACACAAGGACAGTGTCATGGCTGTGCTGGAAGCCTTTGTCTATGACCCACTGCTCAACTGGAGGCTGATGGACA
Seq C2 exon
CAAATACCAAAGGCAATAAGCGGTCCCGGACAAGGACAGACTCCTACTCTGCCGGCCAGTCAGTAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000028991-'91-99,'91-98,92-99
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact

ORF disruption upon sequence exclusion

No structure available
Features
Disorder rate (Iupred):
  C1=0.000 A=0.000 C2=0.478
Domain overlap (PFAM):

C1:
PF0045422=PI3_PI4_kinase=FE(9.6=100)
A:
PF0045422=PI3_PI4_kinase=PD(16.7=91.3)
C2:
NO


Main Inclusion Isoform:


Main Skipping Isoform:
NA


Other Inclusion Isoforms:
NA


Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
ALTERNATIVE
Chicken
(galGal3)
ALTERNATIVE
Zebrafish
(danRer10)
HIGH PSI
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTCGCTATGACCAGAGAGAAA
R:
TACTGACTGGCCGGCAGAGTA
Band lengths:
140-276
Functional annotations
There are 0 annotated functions for this event


GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]


SPECIAL DATASETS

  • Ribosome-engaged transcriptomes of neuronal types
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types