MmuEX6100023 @ mm10
Exon Skipping
Gene
ENSMUSG00000026812 | Tsc1
Description
tuberous sclerosis 1 [Source:MGI Symbol;Acc:MGI:1929183]
Coordinates
chr2:28661582-28663644:+
Coord C1 exon
chr2:28661582-28661685
Coord A exon
chr2:28662461-28662613
Coord C2 exon
chr2:28663500-28663644
Length
153 bp
Sequences
Splice sites
3' ss Seq
TTGATGTTTTACATTTTCAGCAC
3' ss Score
8.39
5' ss Seq
AAGGTAGGA
5' ss Score
9.45
Exon sequences
Seq C1 exon
AACGTGGGCCTATGCTTGTCAACACGTTGGTTGATTATTACCTGGAAACCAATTCTCAGCCGGTATTGCACATCCTGACCACCTTGCAGGAGCCACACGATAAG
Seq A exon
CACCTCTTGGACAAAATTAATGAGTATGTAGGCAAAGCTGCTACCCGTTTATCCATCCTCTCGCTGCTGGGGCATGTTGTGAGACTGCAGCCATCTTGGAAGCATAAGCTCTCTCAAGCACCTCTTCTGCCTTCTTTATTGAAATGTCTCAAG
Seq C2 exon
ATGGACACTGATGTTGTGGTCCTCACAACTGGTGTCTTGGTGTTGATCACCATGCTCCCGATGATCCCGCAGTCAGGGAAGCAGCACCTTCTCGACTTCTTTGACATCTTTGGCCGTCTCTCGTCATGGTGCCTGAAGAAACCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000026812-'9-16,'9-11,13-16=AN
Average complexity
A_S
Mappability confidence:
NA
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF043887=Hamartin=FE(45.9=100)
A:
PF043887=Hamartin=FE(11.0=100)
C2:
PF043887=Hamartin=FE(10.6=100)
Main Skipping Isoform:
ENSMUST00000028155fB18756
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTGGGCCTATGCTTGTCAACA
R:
TTTCTTCAGGCACCATGACGA
Band lengths:
242-395
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types