MmuEX6101112 @ mm10
Exon Skipping
Gene
ENSMUSG00000052155 | Acvr2a
Description
activin receptor IIA [Source:MGI Symbol;Acc:MGI:102806]
Coordinates
chr2:48894666-48898608:+
Coord C1 exon
chr2:48894666-48894780
Coord A exon
chr2:48896972-48897110
Coord C2 exon
chr2:48898478-48898608
Length
139 bp
Sequences
Splice sites
3' ss Seq
GATTTCAAAATCTTTTTTAGGTT
3' ss Score
8.56
5' ss Seq
ATGGTAAGG
5' ss Score
9.33
Exon sequences
Seq C1 exon
GGACATCAAAAGTAAAAATGTGCTGTTGAAAAACAATCTGACAGCTTGCATTGCTGACTTTGGGTTGGCCTTAAAGTTCGAGGCTGGCAAGTCTGCAGGTGACACCCATGGGCAG
Seq A exon
GTTGGTACCCGGAGGTATATGGCTCCAGAGGTGTTGGAGGGTGCTATAAACTTCCAAAGGGACGCATTTCTGAGGATAGATATGTACGCCATGGGATTAGTCCTATGGGAATTGGCTTCTCGTTGCACTGCTGCAGATG
Seq C2 exon
GACCCGTAGATGAGTACATGTTACCATTTGAGGAAGAAATTGGCCAGCATCCATCTCTTGAAGATATGCAGGAAGTTGTTGTGCATAAAAAAAAGAGGCCTGTTTTAAGAGATTATTGGCAGAAACATGCA
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000052155-'12-20,'12-19,14-20
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.058 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0006920=Pkinase=FE(13.2=100)
A:
PF0006920=Pkinase=FE(16.0=100)
C2:
PF0006920=Pkinase=FE(14.9=100)
Main Skipping Isoform:
ENSMUST00000063886fB5350
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGACATCAAAAGTAAAAATGTGCTGT
R:
TGCATGTTTCTGCCAATAATCTCT
Band lengths:
246-385
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types