MmuEX6101710 @ mm9
Exon Skipping
Gene
ENSMUSG00000075318 | Scn2a1
Description
sodium channel, voltage-gated, type II, alpha 1 [Source:MGI Symbol;Acc:MGI:98248]
Coordinates
chr2:65508502-65519144:+
Coord C1 exon
chr2:65508502-65508819
Coord A exon
chr2:65509659-65509777
Coord C2 exon
chr2:65519055-65519144
Length
119 bp
Sequences
Splice sites
3' ss Seq
TGTTGTGTTCTCTTTTTCAGACC
3' ss Score
12.84
5' ss Seq
TTCATATCC
5' ss Score
-14.87
Exon sequences
Seq C1 exon
CACTTTCTTATGCGAGGAGCTAAACAGTGATTAAAGAAGCAGGATGAAAAGATGGCACAATCAGTGCTGGTACCGCCAGGACCTGACAGCTTCCGCTTCTTTACCAGGGAATCCCTTGCTGCTATTGAACAACGCATTGCAGAAGAGAAAGCTAAGAGACCCAAACAGGAACGCAAGGACGAAGACGACGAAAATGGCCCAAAGCCAAATAGTGACTTGGAAGCAGGAAAATCCCTTCCTTTTATTTATGGAGACATTCCTCCAGAGATGGTGTCAGAGCCCCTGGAGGACCTGGACCCCTACTATATCAATAAGAAA
Seq A exon
ACCTTTATAGTATTGAATAAAGGGAAAGCAATCTCTCGGTTCAGTGCCACCTCCGCCCTGTACATTTTAACTCCCTTCAACCCCATTAGAAAATTAGCTATTAAGATTTTGGTACATTC
Seq C2 exon
TTTATTCAATGTGCTTATCATGTGCACAATTCTTACCAACTGTGTATTTATGACCATGAGCAACCCTCCAGACTGGACAAAGAATGTGGA
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000075318-'3-2,'3-1,4-2=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.360 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
PF0052026=Ion_trans=PU(0.7=6.5)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Rat
(rn6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AAGAGACCCAAACAGGAACGC
R:
TCCAGTCTGGAGGGTTGCTC
Band lengths:
242-361
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
Other AS DBs: