MmuEX6101907 @ mm10
Exon Skipping
Gene
ENSMUSG00000027070 | Lrp2
Description
low density lipoprotein receptor-related protein 2 [Source:MGI Symbol;Acc:MGI:95794]
Coordinates
chr2:69499192-69501715:-
Coord C1 exon
chr2:69501487-69501715
Coord A exon
chr2:69500610-69500787
Coord C2 exon
chr2:69499192-69499320
Length
178 bp
Sequences
Splice sites
3' ss Seq
ACTCTGGTTCTGCTTCCCAGGTT
3' ss Score
7.92
5' ss Seq
CTTGTAAGT
5' ss Score
8
Exon sequences
Seq C1 exon
TGACAATGTAATGTTTTGGTCTGACTGGGGTCATCACCCTCGCATTGAGCGGGCCAGCATGGATGGCACCATGCGCACAGTCATTGTCCAGGAAAAGATATACTGGCCCTGTGGCTTAAGTATTGACTACCCCAATCGCCTCATCTACTTCATGGATGCCTATCTTGATTACATTGAATTCTGTGATTATGATGGACAGAACCGAAGGCAGGTCATTGCTAGCGATTTG
Seq A exon
GTTCTCCACCATCCGCACGCTCTTACTCTGTTTGAAGACTCTGTGTTCTGGACTGACCGCGGCACTCACCAGGTCATGCAGGCCAACAAGTGGCACGGGAGGAACCAATCTGTTGTAATGTACAGCGTTCCCCAACCGCTCGGAATAATTGCCATCCATCCCTCCAGGCAACCATCTT
Seq C2 exon
CCCCGAATCCATGTGCCTCTGCCACTTGCAGCCATCTTTGCCTGCTTTCTGCACAGGAGCCTAGACATTACTCTTGTGCTTGTCCCTCAGGGTGGAACCTTTCTGATGATTCTGTCAACTGTGTGAGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000027070-'36-35,'36-33,37-35=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.014 C2=0.000
Domain overlap (PFAM):
C1:
PF0005812=Ldl_recept_b=WD(100=54.5),PF0005812=Ldl_recept_b=PU(69.8=39.0)
A:
PF0005812=Ldl_recept_b=PD(25.6=18.3)
C2:
PF146701=FXa_inhibition=WD(100=84.1)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CGCACAGTCATTGTCCAGGAA
R:
CCTGAGGGACAAGCACAAGAG
Band lengths:
247-425
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types