RnoEX6017271 @ rn6
Exon Skipping
Gene
ENSRNOG00000056184 | Lrp2
Description
LDL receptor related protein 2 [Source:RGD Symbol;Acc:68407]
Coordinates
chr3:55735895-55738448:-
Coord C1 exon
chr3:55738220-55738448
Coord A exon
chr3:55737320-55737497
Coord C2 exon
chr3:55735895-55736023
Length
178 bp
Sequences
Splice sites
3' ss Seq
ACTCTGGTTCTGCTCCCCAGGTT
3' ss Score
8.74
5' ss Seq
CTTGTAAGT
5' ss Score
8
Exon sequences
Seq C1 exon
TGATAATGTAATGTTTTGGTCTGACTGGGGCCATCACCCTCGCATTGAGCGAGCCAGCATGGATGGCACCATGCGCACAGTCATTGTCCAGGAAAAGATCTACTGGCCCTGTGGCTTAAGCATCGACTACCCCAACCGCCTCATCTACTTCATGGATGCCTATCTTGACTACATTGAATTCTGTGATTACGACGGACATAACCGAAGGCAGGTCATTGCTAGCGATTTG
Seq A exon
GTTCTCCACCATCCGCACGCCCTCACTCTGTTCGAAGACTTTGTGTACTGGACTGACCGTGGTACTCGGCAGGTTATGCAGGCCAACAAGTGGCATGGGGGGAACCAGTCAGTTGTAATGTACAGCGTTCACCAACCGCTTGGAATAACTGCCATTCATCCTTCAAGGCAACCACCTT
Seq C2 exon
CCCGGAATCCATGTGCCTCTGCCTCTTGCAGCCATCTTTGCCTGCTTTCTGCACAGGCGCCTAGACATTATTCTTGTGCTTGCCCTTCAGGATGGAACCTCTCCGATGATTCTGTCAACTGTGTGAGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSRNOG00000056184-'39-45,'39-43,40-45=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.042 C2=0.000
Domain overlap (PFAM):
C1:
PF0005812=Ldl_recept_b=WD(100=54.5),PF0005812=Ldl_recept_b=PU(69.8=39.0)
A:
PF0005812=Ldl_recept_b=PD(25.6=18.3)
C2:
PF146701=FXa_inhibition=WD(100=88.6)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CGCACAGTCATTGTCCAGGAA
R:
GGTTCCATCCTGAAGGGCAAG
Band lengths:
255-433
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]