MmuEX6101927 @ mm10
Exon Skipping
Gene
ENSMUSG00000027070 | Lrp2
Description
low density lipoprotein receptor-related protein 2 [Source:MGI Symbol;Acc:MGI:95794]
Coordinates
chr2:69465589-69467281:-
Coord C1 exon
chr2:69466765-69467281
Coord A exon
chr2:69466205-69466357
Coord C2 exon
chr2:69465589-69465759
Length
153 bp
Sequences
Splice sites
3' ss Seq
CCACTGTCTTTCCATTGCAGAAA
3' ss Score
11.7
5' ss Seq
AGGGTATGA
5' ss Score
6.84
Exon sequences
Seq C1 exon
GATTCTTCAATCAGTCATTGTGACCACAACTGTACAGATACCATAACCAGTTTCTACTGTTCCTGTCTTCCTGGGTACAAACTCATGTCTGACAAACGTACTTGCGTGGATATTGACGAGTGCAAGGAGACACCCCAGCTCTGTAGCCAGAAGTGTGAGAATGTCATAGGCTCCTACATTTGTAAGTGTGCCCCTGGCTACATCCGTGAGCCAGATGGGAAGAGCTGCCGGCAGAATAGCAACATTGAGCCCTACCTCGTCTTCAGCAACCGTTATTATATAAGAAACTTAACTATAGATGGCACGTCATACTCTCTGATTTTGCAAGGATTGGGCAATGTTGTGGCCCTGGACTTTGATAGAGTAGAGGAGAGGCTGTATTGGATCGATGCAGAGAAACAAATTATCGAGAGGATGTTTTTGAATAAGACAAACCAGGAGACCATCATAAGCCACAGGTTAAGACGTGCTGAAAGTCTGGCTGTAGACTGGGTCAGCAG
Seq A exon
AAAACTCTATTGGTTGGATGCCATCCTAGATTGCCTGTTTGTCTCTGACCTTGAAGGTCGACAACGCAAAATGCTAGCCCAGCACTGTGTGGATGCAAACAATACCTTCTGTTTTGAAAATCCCAGGGGAATTGTCCTTCATCCTCAAAGAGG
Seq C2 exon
GTATGTCTACTGGGCAGATTGGGGTGATCATGCATACATTGCAAGAATTGGCATGGATGGAACCAATAAGACTGTGATTATCTCTACCAAGATCGAATGGCCCAATGCCATCACCATTGACTACACCAATGATCTCTTGTACTGGGCAGATGCTCACCTGGGTTACATCGA
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000027070-'62-61,'62-60,63-61
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF126622=cEGF=WD(100=13.9),PF146701=FXa_inhibition=WD(100=20.8),PF0005812=Ldl_recept_b=WD(100=23.7),PF0005812=Ldl_recept_b=PU(0.1=0.0)
A:
PF0005812=Ldl_recept_b=WD(100=94.2),PF0005812=Ldl_recept_b=PU(0.1=0.0)
C2:
PF0005812=Ldl_recept_b=WD(100=72.4),PF0005812=Ldl_recept_b=PU(31.7=22.4)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGGCTGTATTGGATCGATGCA
R:
TCAATGGTGATGGCATTGGGC
Band lengths:
248-401
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types