Special

MmuINT0046475 @ mm9

Intron Retention

Gene
ENSMUSG00000026883 | Dab2ip
Description
disabled homolog 2 (Drosophila) interacting protein [Source:MGI Symbol;Acc:MGI:1916851]
Coordinates
chr2:35565338-35568530:+
Coord C1 exon
chr2:35565338-35565892
Coord A exon
chr2:35565893-35568385
Coord C2 exon
chr2:35568386-35568530
Length
2493 bp
Sequences
Splice sites
5' ss Seq
AAGGTGAGT
5' ss Score
10.47
3' ss Seq
CTCCCTTTCTGCCTCCCTAGGAC
3' ss Score
12.48
Exon sequences
Seq C1 exon
GACAACAGCCGGCGTGTGGAGCATATCCTGAAGCTGTGGGTGATTGAGGCCAAGGATCTGCCGGCCAAGAAGAAGTATCTATGTGAACTGTGCCTGGACGATGTGCTGTATGCCCGTACCACAAGCAAGCTCAAGACGGACAATGTCTTCTGGGGAGAGCACTTTGAGTTCCATAACCTGCCGCCTCTACGCACAGTCACTGTGCACCTGTATCGGGAGACTGACAAGAAAAAGAAAAAGGAACGCAACAGCTACCTGGGCCTGGTGAGCCTGCCTGCCGCCTCTGTGGCTGGGCGGCAGTTTGTGGAGAAGTGGTACCCAGTGGTGACACCCAACCCCAAGGGTGGCAAAGGCCCTGGGCCCATGATCCGAATCAAGGCACGCTACCAGACCGTCAGCATCTTGCCTATGGAGATGTACAAGGAGTTTGCGGAGCACATCACTAACCACTACCTGGGGCTGTGCGCAGCCCTGGAACCCATCCTCAGTGCCAAGACCAAGGAGGAGATGGCGTCGGCTCTGGTGCACATCCTGCAGAGCACGGGAAAGGTGAAG
Seq A exon
GTGAGTGTGGCGCTGCTGCAGGAAGGCCGGCTGTCCACGCTTGATGGATCTGGGGTGTTATGATCTGCTTCATTTCGGAGGACTGGGGTATATCCATTTCAGCCACATGGGCTCCCTAAAATTGAGCCTTGTGCCATGCGTTGGGAAAACTTTGTACTCTACCAGTAGCAGTGCCGCGCCCTGAAGGCACTTTGCACAGAGAATAGACCAGAACTAGTAGCGCTGAGTGGGCTCCCCTGCTGTGCTCGTGCTGGAGTGTGCCTGGACTCTTCCAGCATGTAAGCCCAAACCCACATACCAGTGAGATACCGGTTGGCAGCTATTCCCAACAGATGAGCTACCTTCAGAGCCCTGGTCTCAACCCACGCCTTCACATGGAGCTTTACACACAGGTGTACAAGTATGCACACTTCCTAAGTATGCACAGCCAGACATGGTCCTGGTGACTGTAGAAATAGGGATTAGAAAGCCGTGCAGTTGGGCTCTGCTTCAGAGCCAGAGGTACCCAGCTGCTGCTGCTGCCACCTTTTAGTGCTTGCCACTCTTGATCATGGTCCAGAAAGGACACAGCTTGGCTCCACCTAACTGGTCTAGAGAACGGAATATCTCCAGGAGGCACACCATTTCAGTAGCGCATGGTTCTAACGGGCTTTGCTAGTGTGGTGAGATGCTTTCCAGTCACCACTCATTGTCCCTTGGGAATTGCTGTCCACAAAGAGTCAGAGGAAAGGACTTGAGCTCTACTAGCCCCTGCACTATGGGAGACTTGAGGTAACGGGCCAGGGAATGATAAAGTTTTGAGAACGAAGGCTTGTATGAGGATGGGAGTAGAGGGTCACTTTGAGGTAATGTCCTAAGCCCCAGCCTATTGTAGTCAGGGAGGCCCAAGAGGGGAACTGGGTTTGGATGCTCAGTGGGCAGAGCTCAGTGGTCTAAGACTCCATGAACCGTTGATCAACTCTTAACCTCTTCCTAGAGGCCCTGGCAGGGGGAGGCCCTGGTTGGAAGCCCTTTGTCCTCTGCATCCTCCATTGGCTGCTGGACTGACTGGCCCTGCAGAAGGACAGGGAGGGAAAAGGACTTCCTTAGGGAGAGTGCTGCCTTCTTCCATGTCTTCAGGACCCTCTTCCCCATATGCCTGCCTTCAGGCTGGCTGGGTAGGTTGCCAGCTAGGCCAACTCTTGAAATACTGCATGGTTTTTGTTGTTGTTATAGTCTGGTTTTTACATTTTTAAAATTCTATATGTACAGGGACTTTGCTTTGCCTTCATGTATGTCTGAGCACCACATACATGCCTGCTTCCCACAGAGGTCAGAAGAGGGACTAGAGTTACAGACGATTGTGAGCCACCATGTGGGTGCTAGGAGTCAAAGCTGGCTCTGAAGAGCTGCCAGTGCTCTTATTTGCTGAACCAGCTCTCCAGCCCATACAGCCGGGCTTGGCTTTGCTGGTGGTGGTGGGCTAGAGATTCTGGGGAGTTTGAAGAGAGTAAGCTGGAAGGTTTAACCTTCCCTGCTGCTGAGTCTTTTTAGCTCCCAGTCCCAAGGGCTGCTATGGCTTGGGAAGCTGATATATGAAGTAGCCAAGAGGCACACAGAGAATGAAGGGGTAGGAAGTAACTGATGTCTCTGGGTTATTGCCTCAGGAACAATCTAGAACTAGCAGGGCATTCTTGAACCAGATAGAACTCATGCTGAAGACTATTTGTTTGTGAGACACTGCCCTCCCAATGTAGCTGCACTCCGAGGGCCCCAGACCTGAGTCCTGACACCTCTTGCTCGCTCTTAGGTCCTGCTTGTCTAAGCTGTGTGCTTTTCCAGTTCCCATCCTAGGACTCCCCTCTCAGTGAACTTTCTGTGATCTTGGATGCAGAACGTGACCCCAGATGGTTGTGGGGCCTTGGGCAGGTTGTCTATCTGCTCTGTGCCTTGCTTTCTCTCTTCTGCTGCCCACCTCTTAGGATTCATGTCTTACCCCAGTGCTGAGGTCCAGAGCTGTTACAGAACTTCAGGAAGATGGTGGCTTTGGATAGAAGTCATGGTGCTGCTTCAGCAGGGATGGGTCCTTACCTCTGATTGTATTTCCAAGATGTGCGTGGGGTGGGGGTGGGGGTTGTCAACCATAGCTTCCTCTTGGACCCACCTATCTCTCAGCCCTTCCTTTTGTTGGTCATCTGGCCTCCTGGATTAAGGTCTTAATTCTGTATTTCAAAAGATCTTCAAAAGTTGGGCACATTGAAATGAGTTTTGAGAACTCCAGAAACCCTGGCCCATGCTAGATTGCTGGGCATCGTCTCCTGCCCTGTAGACTTTGGGCTTGAGAGGAAGGGAGCTCTCATCCTGTCAGATACCACAGCCAGAGGCAAGGTACAGCTCAGCTCCTCTGCCAGTGTCTTCCCATGGTCAGCTGGGCTGTCCAGCAGCCAAGGACAGTGATGGTTCTGCCAGCTCAGCTCAGTTCAGTTCCACTCTGCTCCCTTTCTGCCTCCCTAG
Seq C2 exon
GACTTTCTAACAGACCTGATGATGTCAGAGGTGGACCGCTGTGGGGACAATGAGCACCTCATCTTCCGGGAGAACACACTGGCCACCAAGGCCATCGAGGAATACCTCAAACTTGTGGGCCAGAAGTACCTGCAGGACGCACTAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000026883-Dab2ip:NM_001114125:6
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact





	

	
ORF disruption upon sequence inclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.022 A=NA C2=0.007
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0016825=C2=WD(100=43.8)

							
A:
NA

							
C2:
PF0061614=RasGAP=PU(27.3=95.9)

						

					

				








    
Main Inclusion Isoform:
NA





     
                   









    
Main Skipping Isoform:
ENSMUSP00000088532





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000088532f2021A
          









    
Other Skipping Isoforms:
ENSMUSP00000028246, ENSMUSP00000068832, ENSMUSP00000108607, ENSMUSP00000108610, ENSMUSP00000108611, ENSMUSP00000108616, ENSMUSP00000119058, ENSMUSP00000121506, ENSMUSP00000122341
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
No conservation detected
Human
(hg19)
chr9:124522719-124525783 
LOW PSI
HsaINT0044766
(DAB2IP)
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
chr11:92641815-92644699 
LOW PSI
BtaINT0046521
(DAB2IP)
Chicken
(galGal4)
chr17:8582525-8589778 
ALTERNATIVE
GgaINT0124829
(DAB2IP)
Chicken
(galGal3)
chr17:9288518-9295773 
LOW PSI
GgaINT0124829
(DAB2IP)
Zebrafish
(danRer10)
chr8:12126614-12145031 
LOW PSI
DreINT0054619
(dab2ipa)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
No suggested primer sequences

				
R: 
No suggested primer sequences

				
Band lengths: 

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






Retrieved from "https://vastdb.crg.eu/wiki/Special:VastDB"