MmuINT0050317 @ mm9
Intron Retention
Gene
ENSMUSG00000030409 | Dmpk
Description
dystrophia myotonica-protein kinase [Source:MGI Symbol;Acc:MGI:94906]
Coordinates
chr7:19676278-19677193:+
Coord C1 exon
chr7:19676278-19676389
Coord A exon
chr7:19676390-19677029
Coord C2 exon
chr7:19677030-19677193
Length
640 bp
Sequences
Splice sites
5' ss Seq
GTGGTGAGT
5' ss Score
8.95
3' ss Seq
ACTCTGATCCCCACCGACAGGCT
3' ss Score
6.6
Exon sequences
Seq C1 exon
AGACAATCAGGTCCCGGACCCCACCCCTATGGAACTAGAGGCCCTGCAGTTGCCTGTGTCAGACTTGCAAGGGCTTGACTTGCAGCCCCCAGTGTCCCCACCGGATCAAGTG
Seq A exon
GTGAGTAGACTGAGAGGTGGGCAAAGCTTCCTGGGTGGGTGTACCTGCAGTGCCAACTGCCAGGCTGTTAATTCAGTAGGACACTGTCCCCAACTGGCCCAACTGCACATCCTGTAGTCAGGAGGCACAGGCAGAAAAATCCCAAATTCAAGGCTTGCTCCCGTTATGTAATGAGATCCTGTCTTGGAGTAAAAAACAAAGAAGAGAACTAGGGATAGCTCAGAGGTAGATGCTCTCCTGGCATGGGGGTGGGGTCAGAAAGCAACACCAACCGGGGCCTGGGAGGGAGGGACTGCCAACCACCTGGAGGAGTCTGGGGTAGACTTGGTGAACAAAGTTCAGAGGCCATCAGGTGGGATGCTGGTTTCTTAAAAGCCACAGATAGGTGGGTAGCATTGGAAAGAGGAGTGGGGGGTTGCAGAAAGTGACAAGACACAAACTGGGGAGGCCTAAGGGTAAAGCCAGGGTTGTCTGAAGCACTGTGGAGCTGGGAGGAACACGCTAAACTTCTGACTTCAGCCCTTCAGTTCCCCTGTTGACTACACTGTCCCCAGGGACCCAGGGATGGGGAGAGGTGGACGGGGGAGGGAAGTACGGGACTGATCCAGCTCCAGGTCCCAACTCTGATCCCCACCGACAG
Seq C2 exon
GCTGAAGAGGCTGACCTAGTGGCTGTCCCTGCCCCTGTGGCTGAGGCAGAGACCACGGTAACGCTGCAGCAGCTCCAGGAAGCCCTGGAAGAAGAGGTTCTCACCCGGCAGAGCCTGAGCCGCGAGCTGGAGGCCATCCGGACCGCCAACCAGAACTTCTCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000030409-Dmpk:NM_001190491:10
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.684 A=NA C2=0.745
Domain overlap (PFAM):
C1:
PF104814=CENP-F_N=PU(21.9=55.3),PF041569=IncA=PU(26.2=84.2)
A:
NA
C2:
PF104814=CENP-F_N=FE(55.7=100),PF041569=IncA=FE(43.2=100),PF0003816=Filament=PU(57.1=80.0),PF088265=DMPK_coil=PU(50.8=56.4),PF139491=ALIX_LYPXL_bnd=PU(41.1=70.9)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGACAATCAGGTCCCGGAC
R:
GAGAAGTTCTGGTTGGCGGTC
Band lengths:
273-913
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types
Other AS DBs: