Special

MmuINT0050709 @ mm9

Intron Retention

Gene
ENSMUSG00000018581 | Dnahc11
Description
dynein, axonemal, heavy chain 11 [Source:MGI Symbol;Acc:MGI:1100864]
Coordinates
chr12:119169607-119172359:-
Coord C1 exon
chr12:119172155-119172359
Coord A exon
chr12:119169772-119172154
Coord C2 exon
chr12:119169607-119169771
Length
2383 bp
Sequences
Splice sites
5' ss Seq
AAGGTAACT
5' ss Score
9.01
3' ss Seq
TTCCTAACATTTTCTACTAGCTG
3' ss Score
5.41
Exon sequences
Seq C1 exon
GTTCATCAGGATTGGCGATAAAGAATGCGAATTCAACAAGAACTTCCGCCTCATCCTACACACAAAACTGGCAAACCCACACTACAAGCCGGAACTACAAGCCCAAACCACCCTTCTCAATTTCACAGTCACAGAAGATGGTCTTGAAGGCCAGCTGCTGGCAGAGGTGGTCAGTATCGAAAGGCCAGATTTGGAGAGGCTAAAG
Seq A exon
GTAACTATTACTGCATCACCCCCAGAACGTACTCCTCACCCCTTCAGCACAGATGACCATGCTAGATGCTTGCCTATGAAGTAAATTCTGTAACTGAGGAAATTCCTCCTGAAAAATGCCAGGTAGCTAGAGGCTGGACCACAATGGAGATGGACCAGAGCTCAGGCTTAGAGTCTGTCAGTTAGCTTCAGCTGTCATTTTCTTGATCTCTAACAGCCCAGAATCCAGATCCAGCCCAATGTGGACCAGCCCAGAAAACTCTATTGGAAAAAACCTGGTGGTTTTCCTTTGCCCGTGGGTACCAATTAAAGATAGCATCTTGGTTAGGGCTTGGACTACTTTCGTCTCTGTGCTGGGATCCCGGCTGGCTTAAGCCTGTGCAGACCTTGCGCATGCTGCCAGATTCTGTGAGTTCTATGTGCAACTCTGTGAGTTCTCTGTTGTATCTGGAAGGCACTGTCTTCCTGAAGTCATTTACCATCTCTGGCTCTTACACTCTTTCTTCTTCCTCTTCTATATAGTTCCCTGAATGCTTTAATGAAGACATTCCATTTGAGACTCAGTGTTCCGAAGTTTCCCATTTTCTGTACATTGTGCATTTGGGGGTTTCTATGTTAGTTTCTCTCTACTGTGAAAAGCTGCTTCTCTGACAATGGACAAGCAAGGTACTGATCTCTGGGTGTTTTGTTTTGTTTTGTTTTGTTTTTTGACATCCTAAATTTTTCTTTTCCGGTTTTAATTCTGTCTAGATTTTGTTTATTGATTTCTTTGCTGGATTCTACTTCCATGTCTTGATTATTTTTATTATTTCATTCCACCATTTGTGTTTTCACAGAGTTCATTAAGGGATTTGTTCAAATCCCCTTTAAGGTCCTTAAACATACTCATAATTCCTGCTTTGAAGTCCTTGTCGTGTGCTTTAGCTATATTGAATTTCTCAGGGCCTACTGTAATAGAGTTGCTGGATTCTAATGGAAGTATATTGTCTTGGCTAGTCCTGTTTGTGGTTTTATGCTGAGATCTGGGCATCTGGAGTAATGACATTTTTTTTAGTATTTCTTGGCACTGATATCTCATCTTGTCTTTGATGAGTGGGTGTTGTGTTCTTTGGATGATGTCCTCTCTGCATCTGAGGAAAATGTGATGGCTGTAGGGGTCCCTGGTAGAGAATTCTTCTGAGTCCAGGGGCTAGTGTAGCCACTAGTTCCTGGCAGAAAGTATTTCTGTAGATTGGCTGCTATCTTAGTTAGGGTTTTACTGCTGTGAACAGATACAATGCCAAGGCAAGTCTCAAAAAGGACAACACTTAATTGGGGCTGGCTTATAGGTTCAGAGGTTTAGTCCATTGTTATCTAGGTGGGAACATGGCAGCATCTAGCATGCTGCAGGCAGACCTGAGAGTCCTATATCTTCATCTGAAAGCTGCTAGTGGCAGATTGACTTTCTGGTAGCTAGAGTGAGATATTTATAAGCCACATCCACAGTGACACACCTACTCCAACAGGGCCACACCTTCTAATCCTGCCACTCCCTGGGCCGTGCATAAACAAACCATCACAGCAGTTGATACAAAGCCATACTGAGCCTTATTCTGAGATTTGTGTTGTGTTTTCAGACAAAGCCTTTGCCTGTGAGAGAGCTCCTCTGTTTCTCTAGGTAGACAGTCTTGTCTGTAGGGCTGGGACTTTGGCATATTTAATATTTGCTGTAGCATGGGAGTCATAGGTTTCAGTTGTCTCCAGTATTGTTGTGTTTGTTTCCTTTCTTTCTGTTGTTTCAGAAGGCTCTGTACATAGGACCTATCAAAATGAGTTTCCTCCCTGCTCTAGGCAACTGTGGTTTATTCTTTAGTCTTTACTGTGAGAATGAGGCCTGCCTCCCAGCAAGAAAACAGAAATGGGGAGGGCTCCCCGTGCCTGGGTACTCAGGAAGGTTTTTACTCTCCTGCAAAGGCCAGGTACAGTTTAAGTTCTGATAGTGACTCTCTGAATTTGCCTGCCCTATTTTTCTGGTGAGAGTTGGCCCAGGACCCCTGTTCTTGGTGAAAGATGATTGATTGCACAGCTCCTTCCTTATTTTGAAATCTTCCTCATAATGAGTCTTCCAAGCTGTTTAAAAGTCAGAACAGAAGCCAGAAATTTCTATTATTTTCTTAAACAGAGCCTTCCTAGAGGTTATTGGTGTTAAATAAGCATCCACATTCTAAACCTTTAGATTCTAACCAATTGTTAACTGTCTGAATTTTTAAATAATTTTGATAGTTGTGATCAGTATGGTGTTTCTTATGGTTGTGCTGACCCCTGTAACTCCCGTGATTATGAGAACTGTCCTGAACAAAGCAGAACTGTCGTCCTTAACCACCGTTCCTAACATTTTCTACTAG
Seq C2 exon
CTGGTTTTGACCAAGCAGCAAAATGACTTTAAGATAGAGCTGAGGCAGCTTGAAGACGACCTTCTCCTGCGCCTCTCTGCTGCTGAGGGGAGCTTCCTGGATGACACAGACCTGGTAGAGCGCCTCGAGACGACCAAGGCCACTGCAGCAGAAATAGAGCACAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000018581-Dnahc11:NM_010060:66
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact





	

	
ORF disruption upon sequence inclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=NA C2=0.055
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF127812=AAA_9=FE(29.8=100)

							
A:
NA

							
C2:
PF127812=AAA_9=PD(22.8=94.5)

						

					

				








    
Main Inclusion Isoform:
NA





     
                   









    
Main Skipping Isoform:
ENSMUSP00000081867





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
ENSMUSP00000135748
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr7:21842749-21852466 
LOW PSI
HsaINT1011352
(DNAH11)
Human
(hg19)
chr7:21882367-21892084 
HsaINT0049353
(DNAH11)
Rat
(rn6)
chr6:145832508-145833658 
LOW PSI
RnoINT0048700
(Dnah11)
Cow
(bosTau6)
chr4:30741667-30742729 
LOW PSI
BtaINT0050295
(DNAH11)
Chicken
(galGal4)
chr18:1141081-1145179 
LOW PSI
GgaINT0127386
(DNAH9)
Chicken
(galGal3)
chr18:1124024-1128604 
LOW PSI
GgaINT0127386
(DNAH9)
Zebrafish
(danRer10)
chr16:19405127-19406603 
LOW PSI
DreINT0009169
(DNAH11)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
No suggested primer sequences

				
R: 
No suggested primer sequences

				
Band lengths: 

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






Retrieved from "https://vastdb.crg.eu/wiki/Special:VastDB"