MmuINT0062916 @ mm9
Intron Retention
Gene
ENSMUSG00000027204 | Fbn1
Description
fibrillin 1 [Source:MGI Symbol;Acc:MGI:95489]
Coordinates
chr2:125132006-125134325:-
Coord C1 exon
chr2:125134206-125134325
Coord A exon
chr2:125132238-125134205
Coord C2 exon
chr2:125132006-125132237
Length
1968 bp
Sequences
Splice sites
5' ss Seq
TAGGCAAGT
5' ss Score
1.91
3' ss Seq
TTGTCTTGTTTTCTCTGCAGATG
3' ss Score
12.53
Exon sequences
Seq C1 exon
ATGTGGACGAGTGTGAGGGTAACCACCGCTGTCAACATGGCTGCCAGAACATCATCGGAGGCTATAGGTGTAGCTGCCCCCAGGGCTACCTCCAGCACTACCAATGGAACCAGTGTGTAG
Seq A exon
GCAAGTAGCTCCTCGTCCTTAAAAGCAGCCTGGTTGCTGGCCCCTCGCAGAGCCTGAACTTCCTTCTGATGTAAAGTTACTGAGCCAACAACAGCCCCCTGAAAGTTTCTCTCTCCCACTTGAAACCAAAGGGAAGTGATAATCTAACAGCATGTGATAGAGTAAGTGACTTTTGGACGTAATGGGGATGAGATGCCCTTAGACTCCTTGACGCCATTATATCTTCCTCTTCTGCTGCACTGTTTGTCATCAGCGCACACTGGGGATCGCTCTATGATATCAAGTTCCTTGAAGATTTACTTTGGTTTCAGGAGGATCGTGGCCAGGTCAGAATAAGGCAATTAAGGTTCGGGGTTCCTGTTGCCCCCAATCCCAAACAGGGCTCAGAAGGCTCAAGAAATAAAGTTATCTAGAGTGAGCACTGTCATGGACTGAAACGGTTCCGCCAGTGTGGTGCTATACAGAGCCGATCTCTTGGACCAGCCTCACCTGTGTGCCCACTCTTAGCTTGTCGAAGGTTCACTTTCCTGGTGGTTGAGTTAGAGGTCAGGGGCCATTAACACCATTCCTTTCTAGAAGCAAATAGCAGATTTCAACTTTCAGCTGGATTGGGACCCATTTGGCCCTACCATAATCAAAAATGGTATCTATAACGTACTTCATTCCTTATTTAAAATAGAGAAAAGAATGTAGACATTGATTGATTGTATCTTTGATTTTTCTAGTTTAGGATCCCTGTAACCTAAGGGACCTTGAATGCAGACTTGAGGTCTTTGGATTTAGAGAATCTTCAAATAGACAAAGCCAGGCTAATGGCTGGATGGAAGGGGAGGGAAAGAGAGAAGGATTTATATCCACAAATAACACTACACACACACACACAAATGACACAAAGTATTTGAATTTATCAGCAAAACTCCTAGGCCTTCCACTTTCCCCACCTATTTACTAACTGCAAATGCATGGCATGAACATAGAAGGGAGATTGTCTGGGGAAAGAAAGGGAATGGAGGCAGAGAAGAGGAGCGTACAGGAGGGGAAATATGGTCAAAGTACACAGCACACTTGGGTGACAACGTCTTACTTAGACTCATCACTGTGAACAACGAATATACACCAATGTAAGTAAGTATTGGTGGGCTGGTGAATCAGTTCGGTGCATAGAGGCAGCTGCTGCTCATCTCACAAGCTTGGAGAAGCCTCCTAATGCTCACAGGACAGTAGGAAGGTTTGTTTAAATGAGTGCAAACCCTGCCCCATGTTACTGCCTGAAATGAGTGCATGGAATCTCTCCCAGCCACATAGGCTTTAGTCATGGCTCAGACACTGGAGCCACAGCTGGTTTGGATAGGCATTCAGAGAGAAAACAGACATACCAGGAGGTATGACTTAGCCTAAGACTGGGCACCTGCAGGCCCTTGCAGAGGTTTTGAAAAGGAAGTATAATTGGGGCAGATAAATGGGGTGGACTCCCCTGTAGGATAGCAACCATCCTTAGACCTGCACATTCAAGCCCAAGAGGAGCCTCTGGGGTTGTGGGTCTCTGCTTTGGGGATATCCATCCTGAGGGCACTTGTGACCCAAGCATACTGATAACTGTCCAGTCTCTTCCAACCCCCTCTGAACTCCAAACTATAACTGTGGTTCTGACTCCTATGGAGCAAAACATACTAGCACTGGCTTTTAGTGAGAACTGGAGTCTGAGGCTCCTCTTAGTGCCATCCTGGGTATTTTGCTGGGAGCATCTAAACTCTTGTACAATATTTAGTCAGCATGGAAAGAGGCTACCTGCCTTCCCTGCCTCTCTCCTGTACTCTCCAAACTGGCCACCCTGCCTGCTTTCTTTTCTGAGAGCCTACTTACATACCTATAGGCCAGCTTGTCAGTCATGAGGAACATGACCTAAATTCCTCCTTAGAATTCTATGGCAAGTATCATACATGTAACGTTGTCTTGTTTTCTCTGCAG
Seq C2 exon
ATGAAAACGAGTGCCTGAGTGCACATGTCTGTGGAGGAGCCTCCTGCCACAACACCCTGGGGAGTTACAAGTGCATGTGTCCCACCGGCTTCCAGTACGAACAGTTCAGTGGAGGCTGCCAAGACATCAATGAGTGTGGCTCATCCCAGGCCCCCTGCAGTTACGGTTGCTCTAATACTGAGGGTGGCTACCTGTGTGGCTGTCCACCAGGATACTTCCGGATAGGCCAAGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000027204-Fbn1:NM_007993:63
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0764510=EGF_CA=WD(100=95.1),PF0764510=EGF_CA=PU(0.1=0.0)
A:
NA
C2:
PF0764510=EGF_CA=WD(100=51.3),PF0764510=EGF_CA=PU(92.3=46.2)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ATGTGGACGAGTGTGAGGGTA
R:
TCCGGAAGTATCCTGGTGGAC
Band lengths:
342-2310
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types
Other AS DBs: