MmuINT0097627 @ mm9
Intron Retention
Gene
ENSMUSG00000024593 | Megf10
Description
multiple EGF-like-domains 10 [Source:MGI Symbol;Acc:MGI:2685177]
Coordinates
chr18:57406188-57412700:+
Coord C1 exon
chr18:57406188-57406324
Coord A exon
chr18:57406325-57412487
Coord C2 exon
chr18:57412488-57412700
Length
6163 bp
Sequences
Splice sites
5' ss Seq
ACGGTAAGG
5' ss Score
10.38
3' ss Seq
TTGGTCTCTTGTTTGAATAGGTG
3' ss Score
8.83
Exon sequences
Seq C1 exon
GGCACAGTGTGTGGTCAGCCCTGCCCTGAGGGTCGCTTTGGAAAGAACTGTTCCCAAGAATGCCAGTGTCACAATGGAGGAACGTGTGATGCTGCCACAGGCCAGTGTCACTGCAGCCCAGGATACACAGGGGAACG
Seq A exon
GTAAGGACACACTCGTGTTTCTCTGACTGCTCATAATGAATAAGATTCTAATTATCCTAATTAGAAGGAAAGTTTGGAGAGTCCAGGGAGTGTGCTCAGCATCATGTGTCTATAACTGCTATCTAATACTTCAGAAGCATCCATGAAGTCTAAAAGTGTTTGAAAACCTCTATCCTCATGGAGTGTATAGAAACCGAGTCACAGAACAATAATAATGAATTGGAGGAAATCAGAGAGACGTTAGAAAAAAAGACAATAAAACGTCAGCTGGTCACAACCCATGACAAAGGTGTCATTTGAAATGTTGAGTGTTCAGCAAGATTTTGCTGAAAGGACCCTGATATAGCTGTCTCTTGTGAGGCTATGCCGGTGCCTGGCAAACACAGACATGGATGCTCACAGTTAGCTATTGGATGGAACACAGGGCCCCCAATGGAAGAGCTAGAGAAAGTACCCAAGGAGCTGAAGGGTTCTGCAATCCTATAGGTGGAACAACAATATGAACTAACCAGTACCCCCAGAGCTCGTGTGTCTAGCTGCATATGTAGCAGAAGATGGCCTAGTCGGCCATCATTGGGAAGAGAGGCCTTTTGGTCTTGCAAACTTTATATGCCCCAGTACAGGGGAGCACCAGGGCCAAGAAGTGGGAGTGGGTGGGTAGGGGAGAGGGGGGTAGGGGGGACTTTTGGGATAGCATTTGAAATGTAAAATAAGAAAATACCTAATTAAAAAAACAAAAAGAAAAAAGAAAGAAATGTTGAGTGTTTAGGACAGACACCTGACATTTTCAACATTTTTAGATAGATTTGAGATATGTGGAACTGGCATATGAGGAACGGGGTGATTGACAGGTTGATTTTCAAATGGAACGTGTACTTACGGTCTTATATAAAGTATAGCTTCCTTTTCATTGCCCAGAATATCCTTAAGAATGTTACTCACTGGGGACAGAGAGAGATGGCTCCATGAGTAAATGCATACTGCCTTTGCAGAGGGAGGACTTGAATTCGCTTCCTGGCATCCATGTCAGATGGTTCACAACTACCAGTAACCCTTGTACCTCTGACCTCTGCAGGAACTTATACTCAGGACTACATACCACACACAGGCACATGTGAACACACACACACATCATCATCTAAATAAAAAAAAGAGTCATTATATTTACTCTATTGTGTGGAGGGGACAGCACCAGTTCTGTGGGAGAACTTAGAAGTCTGTGAGCCGTGTGAAGCGAGAAGCAAATGGTTGATTTTGCTCTGTCTGTGCTCCTGCAGCTCTTCCATGCCTGGTTGGCCACTTCTTGTATTAAAGGGCAAACTGTTACCTCAGTGGCTCTTCTTGCCCTGCCTCTTCAACTTTGCTCTAGGTCCTAGGAGACTGGACAGCTGAGTTCATTGCCTATGGCATGGAGTCACAGTACAGTGACCTGAGAGGCCAACGGGCAGGCTGCCTAAGAACGAAGAGCCCATGTCCTTGTAATGCTTAGGATGACACTATTCCTCCAGCGTATGATAAGATTTATTAAACTGAAGGTCTTGGAGCAGTCCTGAAGCTTATCCACAAAGCTTTTGTGACTGGGTAGTGTGCAGGAACCATGCAAACACTAGCAATTGTGCATTTGGCTAATATCTAGGAACATTGTATAATTACATACCACTGTATTTTAATGATGTATGTAAACTAAAAAGGCCTTTTTATCCAAATGGTAAAGTAAGGATTAGATTAAGAAGCAAATATTTGAAAGCAAGTTTTCCTTTATCTAGAAAATGCCCAGTTAGATACTTAAAGATAATTTTTAATTACAAAATACTTAGAAAATGCATTTAATAAGTAAATATAGACACTGCCTAGAGAGGTGGAGAAGCTCATAGTATTTAATTGAAAGCCATAAAATTAAAGTAGAAATTCGGATTAAGATAATTAAAAATTATCTTTAAGTATCTAACTGGGCATTTTCTAGATAAAGGAAAACTTGCTTTCAAATATTTGCTTCTTAATCTAATCCTTACTTTACCAATTTTTAAATTAATTTAAGCGTTTTTAGCAAAGACTGGAATTGTTTAGTTTTGCAAAGATAGTATCCTCCACTAAAGATGGCTGGTTTCAAAATATTGCTAATGATTCGCTCACTTCCTTATTTTATTTATTTGACGCTCTGAATTGCTGCTGACCGATGGGAGGTCAATGTGGGAATTCTTCCATGTTGGAGATTCTGTTGAGTAATTATATGTTTGCTGTTTCCAGTTACTATGTTACCACAGTGTCTCTTTTCCAGTCCTTCATTTTGTTAAGATCTTTTGTTAGAAGTAGCCACTTAATTTAATTAAAAGCCATTTTTTTGTTTATTAATACAATGATATAATTTCCTTTTGCTGTTTTGACTTATGAATTATAGACACCTTGATTATCCATTTTACAGTGTAGGACTGAGCTACTCCATGTGACTTTGTGATTCTCCAGCCTAGCTCTAAGCTGTGCTTAGACATTTATATTACAGAAAACAGGGTCAGGAAAAGGAGAGGAACAAAGCCAAGGTGGATTCAAGCAGTGTTCTATAATAATGTTTTAGGCTCTAGAGATTTTAGAAACCTCACACCTCCAAGGCCAGTGAACACGTGCTTAGCGAAGTCAGAACACGGGGGAAGAGAACAGCTAATTTTCAAGTAAAAATCTGAAACTCAAGGAATGGGGAAAATGAGGTGGGACTGGACAGTTGTTCTACGCAAGCTTTTGTGGAGCATTGGCGATGGATGATGCCCTGTGGTTACGGTTTTCCATTGCTGTTCTTGCCTCTGTTTTGAGTTATTAACATATGCAATCCATGGTATGCAGAATGCACATTTGTCTCTATGAAAGATGACAGGGAGTGGCTGTGGGCAGTTTGTGGCAGGAGGTGGGGAGGAGATGCAAGGGTGGGGATCGTAAGTATCCCTTCACTTGTCTTGAGACGTCTGTGTGCCTGGAGTGGTTAGGAGGGGCTGCTCCACAGAGGCTGCCACCGCAGGCAGCTGCCAGCAAATACACCCAGGATGTGGGGCCGCCACCCCACCACAGGGAAACAAGTGGTGAGCTCTGCAGGCTGACGGGACAGCACAGCAGATGACAAATAAGAGGCTTTGAGGTCTGTGGAAAGACCGAAAAGGACACTGTGGTAAGGAGATACAATCCAGCGAAGTCGTCAAGAGTGAGGGGGAGATGATCTGAGGTCCTCACAAAACTCTGCTTGAAGACGCTTTAGAAGGCGCTAATGGTATCACGGGGTCACTCTGTGGTTCTTTGATGATAAGGCAGGGCCCGTGACTATAAAGTGTGCTCAGTGAGTATTCACAACTCAGTAAAGGAGTCTGCTATAGTGAACCCCAAGACAGCCCTGCCAGACCTGTGTTCTGCACGATTCCGAGAGTGAAGTAAAGCTCAGGGGCACAAAGTCAGGAACTGCAGCCCAGGATTGGAGGAGAACAGCGCTGGTCTTCAATGCCAGGCCACTCTGTCTCTGTGACTGTGGAAAAGGTGGCTCTTTCCCAATTCCTTTGCCCCCCCCCCCCCCCCGCGGCAGCTCCAGATGTTACAAAGGCAGGCTGCTGACCCTGCAGTCCAGGTCTAATGAAGCATATGAGTCTTGCACACTGAATCATGATTCAGCTCGGCTATTCCGGTGACACTGGGACGTGACATGCTCCAAAGGACAAGAAGGAGCTGCCACCGTGACTTCATCCCCAAGCTCACAGAGTGAGACAAAGTAGGAATCAGAATGGTATCGGTGTAAGGATGTTCCCTACTAATTAGTGTTTTGTCAGGTTTTGTCTACTTAATGATCATTCTTTTTCCTTACTCCAAACACTATTAGAAATTTCTTTCTTCTTTTCTTTTTAATAGAAATAGTCTTTTTAAAAAAATAGCAATAGTTTAATAGAAATAGGTTTTTTTTATATATTTCTTTTCTGGTCAATTTTTATTACCCTCTGTTATTTCTCTGCCAACATTTTCTTCTGAAGAAAAATGTATTACTGATTTCCGAGATAGCCCTTCTTAATTTTCTTGTGGTACCATAACAGCAACTTGAACGGTTTGCAGGGGAAATGGTGATCTTAAGCTAGAGACCAAGCAGAGAGTCATAGCCACTCCGTGATGTCTATTTAAATAGAAAATGTTTGGTATGCACAGAGTCATCACACTGCACCTTATGTGTATAACTATGTGTATAGTTATAACAGTGATTTAAAAACCACAGGAAAAGTCTCCTCTAGAAAGCTGCCGTCTGCTTGAGTTTCCCAGGTGTGCACACCTAACCATGATTGACAGGAAGGTGCTGCGGTATTGACGGAGGGAACCTGCTGCCATAGCTACGGCTTAGACGGCAAACCCGAGTGAATTCGTTCTACATTTATATTAGAAACTACTAGATCTTTAATTAGAGGCTAGAAAGATAAATACAGGCCGAGATCGGCTATTATACATTTTGCTTTCCAAGAGAAAGAAAATAGTGTGCCAAGTCACAATGAGACCGACAAATTAGTTCCCTGTGATGGGGCAACGTGACTTTGCTAGACATCCGACATGCACCACTTCCAACAGCCTTTACATCATGCTTAAACCACTTTAAAATCATGCAGATAACCCAAGCTCCAACCTTTTCTTGATTAACACTAATAACACTTATGTATTCACTGTGCGTGCTGGGATGGGGTCGCACAGAACAACTTGAGGAAGTCCGGTTCCTCCATCACGTGACTTCTGGGATCGCATTCAGGCTATTAGGTGTCTTTCCCCACTGAATCATCCCACCAACCAGAAGTTTAACATTTTGTTTTGTTTATAAGTTTATGGAAGAGGGTGAGGAACTGGTAATTTTTTTCCACTGGCGTTGAGTTGTATAAGGGTATCTTGTCCGACAAACTGCGAAGCAATTTGCCTTTAGGAAAAAACAAAAAATCAAAAAAACAAAAACAAAAACAAAAACAAAAAACAATAAAACTAAAACAAAACCGCCTGGATCAGGTAAATCACTGTACCTCACCCAGTCTTTTTCTAAAGTGTACCTTTTAAAGGAACAAATCAGATGACTTGGTGTATAAAAGCATCTTGAAGGTTAAAAAATATTCATGTGCATACAGAAAAAAACACCACAGAACAAAGACACAACCTCAGAGTAAAGGGGTGGAAAAAAGTTGTAAAAAAAAAAAAATCATGGCCTTTATAAAAATACTATGGTCTGAAAAATAGCTATACTTGTTCATGGGTAGCTCTAAAGTCTACAACTGAATTCTTTTGAAGAATTCATTCTGCTACTCCAGAATTTCTCTTGTGGTTAAGCTCTCAGTGGCAGCAGGCTGACAAGTGCAGTGAGAGAGTTCTAGGAGCAGTGAAACTTGATCTTAGGAGCCCCTCTTTGCATTTCTTCATCAAGTGTAGTGCAGACTGGAGCCAGAGTCAACCAGCAAAACGTTAGAAGACTCCCAAGCTTTCCCCTCTATACTTAGCATCCCAATATCGACGCTCGCCACACCCTAGCATTAGAACTGTGCCCAGCCTGGTAGAAAGGCTGTTTCTCTTGGAACTGCTTCTGTGCCATTGCTTCTAAGCAGGTCTTGCTGCTTGCACGGTTCAGATCTGGAAAACACAAGACTGACCTACATTTAAAAAAAAAAAATCAGAGTCTGGCATGGCAGGAAAGCCACATGGGAAGTGTCTGCTGAGACAGTGACCCCTACTGTGCTGTGTGCTCCGCTAGATGAGACTGCATGTCTGTCTTCTTGGCAGAATCCTCCCAATCGCCTCACCTCTCCAAAAGGAGATTTGGCTGGCCCCGTTAACTATTCATGCTTTCTATGAAGTAGCTAGGGATCCTTTCACTCCTCCAGGGACCAGCCTCCCTCCTCAAGCAGCTTACCAAAGTATCCCCCCTCTCTGAGCCATTGCTTCTTCCTTATAAAGACTCTAAGGTGAAACCTATAAACTTTATAACCTATAAACTGGGGTAGAGGGCCTCTGATTTTGGAAGGTTCAGAATTCCTCGAGTCTTTGTATTTAGTTCTCCTGCTACAGATCGATCCATCTCGTTACTTTCCTATGGAATAAATACGAAATACTATGGGTTCACAAAGCATTTCGACCTGTATGCAATTAGGTTGAACCAACTATTGGTCTCTTGTTTGAATAG
Seq C2 exon
GTGTCAGGACGAATGTCCTGTTGGGAGCTATGGAGTTCGCTGTGCTGAGGCCTGCAGGTGTGTCAACGGAGGCAAGTGTTACCACGTGAGTGGTACATGCCTGTGCGAAGCAGGCTTTTCGGGTGAACTTTGCGAGGCGCGCCTGTGTCCCGAGGGGCTTTACGGCATCAAATGTGACAAGCGGTGCCCCTGCCACCTGGACAACACTCACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000024593-Megf10:NM_001001979:8
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF079748=EGF_2=PU(93.5=63.0)
A:
NA
C2:
PF079748=EGF_2=PD(3.2=1.4),PF0005319=Laminin_EGF=PU(25.0=18.1)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types
Other AS DBs: