Special

MmuINT0102059 @ mm9

Intron Retention

Gene
ENSMUSG00000028991 | Mtor
Description
mechanistic target of rapamycin (serine/threonine kinase) [Source:MGI Symbol;Acc:MGI:1928394]
Coordinates
chr4:147895401-147898683:+
Coord C1 exon
chr4:147895401-147895501
Coord A exon
chr4:147895502-147898567
Coord C2 exon
chr4:147898568-147898683
Length
3066 bp
Sequences
Splice sites
5' ss Seq
TAGGTAAGC
5' ss Score
8.89
3' ss Seq
TCGTGTGTTTGTTTTCCTAGGTC
3' ss Score
10
Exon sequences
Seq C1 exon
GGGCCAGCTTCATCAGCAGTGCTGTGAAAAGTGGACTCTGGTTAATGATGAGACCCAGGCTAAGATGGCCCGGATGGCTGCTGCTGCAGCGTGGGGTTTAG
Seq A exon
GTAAGCCAAGTTGGGGGCTTTGGTATATCAAAGAATGAGCTGCCATGATGCAGGGATAACAGTCTGTAAGAATGTAAAGGCCATCCCTGCCAATGTACTGATGCCTTCCATCAGTCCATTTTCACTGTCATTTTGACAAACTCCTGAGGCATGGGTAAAAATAGCTCAGTAAGCGAGATTGGGATTGAGATGTGGGTAAGCTATCACCCCTTACAGTTCAGGGACTCAGGCCCACATGCCTACACTCATGTTTGACACCAGTGGCATTGCTCTCCTCTTACAGGAAACAACAGGATGCCTCCAAAGTCCAGCTCTGTGAATGCCTGTGGCATCCCTTATAGCAATATGGGTCAGGGGTAGCTTATAAAAGCCCACCCCAGCTAGGTAGCAGCTCATGAAAACGTTCACTGCACAATTTGCAGATAGCTAAACAGGTTGGAGTCTCTGGCAGGCAGCTCAGCTTGTCTTGAGTGTCAAAACATCTTAGTGCTTGGGGATGGAGGGAGGGGCTGGTGCAGATGATGAGTTTCAGGAACTTCCTGGAGCTTTCGAGTTTGGTTACTTCAGGAGTTTTCAGAGCTTCCTGGCAGCTTGGACCACCCCACACCCAACCCTCCTTCAAAACATCCTAAGTCCTAAGGAGCTTTCCTCGGAGATGGCATCTTTATCTCAGAGGAAATTGCTGCAGCACACCAGCTTGTGGGTGGGTTGCAGTCCTAGTATCTTTTTTTTTTTTTAAAGATTTATTTATTATTATATGTAAGTACACTGTAGCTGTCTTCAGACACACCAGAAGGGGGAGTCAGATCTTGTTACGGATGGTTGTGAGCCACCATGTGGTTGCTGGGATTTGAACTCTGGACCTTCGGAAGAGCAGTCGGGCGCTCTTACCCACTGAGCCATCTCACCAGCCCCAGTCCTAGTATCTTGTTAAAAAAAAACAGTCTTGCCCCACAGGAAACTCCAGGGTTTTAGAAGCCCTGTGACAGGAAACAGGGATAAGGAAGTAGATGTATTTATGTCGTGGTGGAATTTGGCACTTGGCTTTCTTGCCTTAGCTTTCCCTGCCACCTGTGTGTGCGGTACCTTTTCACCACGTGATCTGTACGTTGTTAGAGCACCACCTATCCCCTGTGCCTCAGATAGGATAGAAGGCCTGTCTCGCTTCTTTTCTTTTCTTTTCCTTTCTTTTCTTTTCAAGATTTATTTATTTATTATATGTAAGTACACTGTAGCTGTTTTCAGACACTCCAGAAGAGGGCATCAGATCTCGCTACAGATGGTTGTGAGCCACCATGTGGTTGCTAGGAATTGAACTCAGGACCTTCAGAAGAGCAGTCGGTGCTCTTACTCACTGAACCGTCTCACCAGCCCCCTCACTTTGTTTCTTAATGTTTATAGGTCTTTCACTACGTGTATAACTGACTGGGACAATAATGTCCCACATGCCACCACCTTCTCCAACAGTCACAAACATTTCAATCACGTTTTATCGGTTTTCCCTGCTACTAGAGCCTGTTATAAAGATATTTTGTTTATTTTTTAGATGGAGTTTCATCTTGTGGCCCTGGCTGTCGTGGAACTCACCACCTGCCTCTGCCTCCCCAGTGCTGGATTAAAGGTGCACTCTGCCTTGCCTGTCCAGATATGTAGACTTTTGACACCACCTAACTGAGGCTTCCGGGTCTTTTTCTTTTTGTTTATTTGCTCTTTTTTTTGGTGTTTGTTTGTTTGTTTGTTTGTTTGTTTCGAGACAGGGTTTCTCTGTATAGCCCTGGCTTTCCTGGAACTCACTTTGTAGACCAGGCTGGTCTTGAACTCAGAAATCCACCTGCCTCTGCCTCCCGAGTGCTGGGATTAAAGGCGTGCGCAACCATGCTTGGCTGTTTGCTCATTTTTAATTGTGTTTATGTGTCTGTAGCTCTAAGCATGTGAGTGCAGGTGTCAGAGGGGCCACAGGGTCAGATCCTCCTGGAGCTGGAGTTAGGGGTGGTTGTGAGACAACCTCATGTAGGTTCTGGGAACCAAACTCTGCTTCCCTCCAAGAGCCGTATAAGCTCTTCACTGCTGAGCCATTCCTCTAGCCTCCAACTCTGCATTTCTAGATGGGACAGGAGAGGAGAGACAGGATGTGGCGTGTGCAGAACCATCCCCGGAGCCTAGAGCAGAGTAGCAACTGCCCCACAGCCCCCCTAGTCACTGCGCTTCTATGCTTTGCTGTCGTAAGCCCTGGGCTTCGTCCAGAATGGCTTTTAAAAACAAATTGCTTCCTGAGGAGTCATCTATTGCTGTCTGCTTTTGCCCAGAGGCATTGGTAATGGATGAACCAATAGTTGGGAGTGGAATGCTGGAAAATGCCTTGTAAAAACAGCAGCCCTGCAGTTTGCACCTAATGAGGCTGGTATCTCTTCTGCAGATGGTGTTGGCAGGACTGACGTTGGGTGCCTGCTCAGCACCAGGGGAGGAAGTACATACCTCTCCCTGGGGCAGCCATTTCTCCATTCTAACATGACACAAGAGATCACTGCGCAGTGACCAGCCCGTCTCTCTGCTGTAATGGATTATTTTTAAATATTTGTGGCTAGGATATTGCCACAGTGAAAAGGGCAAACAGTTTGTCAAAACCTGTCCTCTAATTGTATGATGGCCATTTTCAATTGCTTAAAGGAAAATGTAATTTCCCAGTATTTCATTGAGCTGTGAGGTGCTCACTTGTAGGGAAGAATGTGATTTTGTCTTACCTGGAGAAGCTGTGAAGGGAGCTCTATGGGTTAATGAGGGGTAGCATTAAGCCTGTCTGATGTGCTGGCTTTGCATTTAGGCCCTGCTTCTTGTCTTATGATACTCCCTGGGGCACCAGCAGAGTCCCTCGCTTAGAAGACAGATGTGGTTTTGTTAAGTGAACCACCCACAGTAGATTGCAGGGCTCAGCAGGTACATCAGGCCCCAGTCCATTTGACTTGTGTGTATCTCAAGCTAAGTGAAGGTATCAATGACAAGATTTGGTGGTGCCTCCAATTGAGCCAGCTGTCCCCCTGACTCTGTGTCGTGTGTTTGTTTTCCTAG
Seq C2 exon
GTCAGTGGGACAGCATGGAGGAGTACACCTGCATGATCCCACGGGACACCCACGATGGAGCCTTTTACAGGGCAGTGTTGGCTCTACATCAGGATCTCTTCTCCTTGGCCCAGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000028991-Mtor:NM_020009:31
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact





	

	
ORF disruption upon sequence inclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=NA C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF134141=TPR_11=PD(19.4=34.3),PF0225918=FAT=PU(2.8=31.4)

							
A:
NA

							
C2:
PF0225918=FAT=FE(9.6=100)

						

					

				








    
Main Inclusion Isoform:
NA





     
                   









    
Main Skipping Isoform:
ENSMUSP00000099510





     
      









    
Other Inclusion Isoforms:
ENSMUSP00000099510f2489A
          









    
Other Skipping Isoforms:
ENSMUSP00000099510f2490A
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr1:11146792-11150125 
ALTERNATIVE
HsaINT0106385
(MTOR)
Human
(hg19)
chr1:11206849-11210182 
ALTERNATIVE
HsaINT0106385
(MTOR)
Rat
(rn6)
chr5:165335370-165338224 
LOW PSI
RnoINT0095466
(Mtor)
Cow
(bosTau6)
chr16:43364065-43365750 
LOW PSI
BtaINT0096217
(MTOR)
Chicken
(galGal4)
chr21:4153879-4154762 
ALTERNATIVE
GgaINT0133926
(MTOR)
Chicken
(galGal3)
chr21:4154548-4155431 
LOW PSI
GgaINT0133926
(MTOR)
Zebrafish
(danRer10)
chr8:46162834-46164950 
LOW PSI
DreINT0098829
(mtor)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
No suggested primer sequences

				
R: 
No suggested primer sequences

				
Band lengths: 

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






Retrieved from "https://vastdb.crg.eu/wiki/Special:VastDB"