Special

MmuINT0104593 @ mm9

Intron Retention

Gene
ENSMUSG00000024388 | Myo7b
Description
myosin VIIB [Source:MGI Symbol;Acc:MGI:107709]
Coordinates
chr18:32154438-32157812:-
Coord C1 exon
chr18:32157677-32157812
Coord A exon
chr18:32154602-32157676
Coord C2 exon
chr18:32154438-32154601
Length
3075 bp
Sequences
Splice sites
5' ss Seq
AAGGTGAGC
5' ss Score
9.6
3' ss Seq
TAGCCCTGATGTCCCCACAGGCT
3' ss Score
7.29
Exon sequences
Seq C1 exon
GGGACAGATGTCACTATGCTGCAGAAACTGAACAGTATCCATGCCAACAACAAGTCCTTCCTGAGCCCCAGGAGCATCCATGACACCCGATTTGGGATCGCACACTTCGCGGGCGATGTATACTACCAGGCAGAAG
Seq A exon
GTGAGCATAGCTCTGTGTCTGACCTACTAGGAGCCAACTCAGGATCCCACAGGAAGGAGGAAGCCAGGGAACCGAGGATGAAGCAGACTGCTGCTCAGCCTCCTTTCCCTGCTTACACAGTCCAGGACCCCAGCCAGGGGAGGCGCTACCCACTGTGGGTGGGTCTTTCTGCTTCAGTTAATGTAGCATAGATAATCAATCCTCCACAGGCTGGCCAGTCTACCAGGTGATTCTAACTTCTGTCAAATGGTAAAACACTAACCATTGCATATGCCATGTATGCTCTCTGAGGCTGGTTTCTTTCACTTACTCAAAGGTGTTTGTTTTTTGTTTTTTGGGCTTTTGGGTCTTTGTTTGTTTTTGAGACAGGGTTTCTCCGTGTAGCCTTGGTTGTTTCAGAACTCACTCTGTAGACCAGGCTGATCTCAAATGTACAGAAATCTGCCTGCCCCTGCCTCCCAAGTGCTGGGATTGAAGGCATGTGCCACCATGCCTGGCTATACTCTGAGGTTGGTCTGTGTTAATGTAGTTGCTGGGGATCAAACCCAAGTCCCCCACTTGCTCACTGAGCTCTTTCCTGTCATCTCCCCAGACCTCTCTGTTCCTTTTTATTGCAGAAGAATATTTTGTTTCTCTCTTCAATTGATGGATGTTTGAATTGTTTCTCCGTTACAGCTATTTTATATAACACAGCTGTGACCGGCCATCTTTATGTGGACGTAGATTTCAGTTAGCTCAGCATATATCTAGCTAGGTCATGTACAGGGGCACATGTGGGGCACCCACCAAACTCTTTCTCAAAGTAGCTGTGTTATTTTACACTCCTAATAGGTGTGTGTCAGAGTACCAACCTTTCTGCATCCTCTTGAACTTGTGATGTCAGAGGCTGCCTTGCAGGAGTCTGTCCTCTCCTCTCATAGTGCGGGGCCTGGGGATGGAACTCAGGCTATCAGACTTGGCAGCGAGTGTCTTTTCCTGCTTAGCCGTCTCTCTGGCCTATAATAATACTTTCTATATTTTGACTGTAAGTACCTCCTCAGATATATAGTTCGTAAAACTTTTCTCATGCCGAGGGGACCGTCTTTTCATGTTTGCTTTGGTGGCTGTGGATGGAGCTCAGGGCCTGACACAAGGTGCAAGTGTTCCTTCCCACTGAGCTATGTCCCAAGTCTTTGATTTTCCTGTTGTTGTTGTTGTTGTTGTTGTGTTATTTGCCACCAGAAGGTGTGGTTGGGATAGGGTGGGTCTTCTGACTTCAAATGATCCAGATTTAGGGTGGATCTTCCCACTTCAAAAATGATCCTATTAAGCAAAATTCCCCACGGGCATGGCTAGCTGCTTGGAGTTTAGTTGATTCCAGATATAGTCAAGTTAATAACCAATATTAGCAACCATAGTCCCAGAACCCAAAGAGGACACTGAACCCATTCCCCCACACCCCTGTGTGTGTTTAAGAGTGAGGTTTTGTTTGTTCCTTTGTTTTCATGCTTGCTTCTGTAAGTGACATGAAACTTAAAAGGATGCTAAGATTCAGGAAACTTCTTTCTCTGAGCATGAGGATCTAATTTAGAACACCCAAAATTCATGAAAACCAGACACATCTCACATCCATTGTCTCAGCACTGCTGTGGGGAAATGGGAAACAGACAGGGGAATCATTGGATGTTCAAAGACCAGCTAGCCTGGCGTGCACAGTTCTGAATAACAAAAGATCCAGCCTCAAATGAGACAGAAGGGCTGTCCTCTGACCACCACACAGGCACCATAGCATGCTCACGCCTACACTCTCACACATGAGTGCACACACTCTCTCTCTAGCACAAACAGAAACATACACAAACACACATGCACACACACACATGCATGCACACACACATTTTTAGAAACAGGCTTGGGTATTTAGCTCAGAGTGTTTGCCTTGCAAATGAAGCCCTGGCATTTTATCCCCAGTACCAGTAAACCAGGCACAGTGGTACATGCCTGTAATCCCAGCAGTCAGGAGGTGGAAGCAGGAGGATTACACATTCAAGATCATCCTTGGCTACAAAGCAATTGGGGAGCTATACGAGACCTGGCCTCAACAAAACAAAGCAAAAAGCAAAACATGAACCATAAAGCAACAAACAAAAATGCTAAAGGTCTTGTTTTCATCTGGGGTACTCTGTTGTGCTCATGGCTCATAGGTAGCCATCTGTCCTTGTGACCGCACACAGTCCTCTCTCGGTGTATCTATGTACTGATACCTTCTTTTAATGACACAGGCCATACTGGGTCAAGGCCCACTATCTTGACTACATTTTATGTTAATCATTAAGCCAGGCCGAGGTGGTAGCTCAGTTAATAAAGTGATTTCTATGCAAATATGATGACTGAAGTCCATCCTCAGAAATCACATTTAAGAAAAAAAAAGCTGGACTTAGTGTGCCCCCTGTAACCCCAGCACTGGGGAGGCAGAAACAAGCAGACCCTTGGGCTCACTGGATAGCAGCTTAGCCTATTTGGTGAACTCCAGGCTAATGAGTGACACTGTCAAAAAAAAAAAAAAAGTGGGCATCCCCTGAGGAGTGTTCTCTGACCTCCACATACACAGGAACAAATGGGTACCGCTCTTAAACAAGCATGCACATACACACACACATGAAGCCTCCTCTTCAAACACAGGCAATCCATTCTGGATCTATACATACTGGAACCAAGGACTCCAGCAAATTAATTCAGGTGGATACGATTCAGTTCAAAACACTGGCCTCCCTCATTTCTGAAGGCTAGGTCTTTCCGTTGGAAGAGTTTCAACCCTATCTGAATGCCCAAGACCATAGAAACAGCATAATGTATTCATTGAGACCACAGTGCTGAGTGGGGATGCAGCCAGTGCTCCCAACCTCTGTGCTGTCTCTCCAGCCCCAGGGGGTGAGAGTTCAGAGGTCAGAAGTGACTTAGTGATGGATGGGACAGAAGCTCTAGACAGTATGCTTCAGTGGGACATTCTGGAAACCCTCTAGGCAAGCTCGACTTATTCAAGGGACGGAGGGCATAGCTGAGCTGGCCTGGAGGATAGCCCTGATGTCCCCACAG
Seq C2 exon
GCTTTCTGGAGAAGAATCGAGATGTGCTGAGCACAGATATCCTAATCCTGATTCATTCCTCGAAAAACAAGTTTCTGAAGGAGATATTTAACGTGGACTCATCACAGACTAAGCTGGGGCACGGCACCATCTGCCAGGTGAAGGCAGGAAGCCAGCTCTTCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000024388-Myo7b:NM_032394:14
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact





	

	
ORF disruption upon sequence inclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=NA C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0006316=Myosin_head=FE(6.6=100)

							
A:
NA

							
C2:
PF0006316=Myosin_head=FE(7.9=100)

						

					

				








    
Main Inclusion Isoform:
NA





     
                   









    
Main Skipping Isoform:
ENSMUSP00000118046





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
NA
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr2:127584914-127588391 
LOW PSI
HsaINT0108954
(MYO7B)
Human
(hg19)
chr2:128342489-128345966 
LOW PSI
HsaINT0108954
(MYO7B)
Rat
(rn6)
chr18:24784886-24789379 
LOW PSI
RnoINT0097418
(Myo7b)
Cow
(bosTau6)
chr2:4869865-4874128 
LOW PSI
BtaINT0098312
(MYO7B)
Chicken
(galGal4)
chr9:846576-846845 
LOW PSI
GgaINT0031401
(MYO7B)
Chicken
(galGal3)
chr9:2280573-2280842 
LOW PSI
GgaINT0031401
(MYO7B)
Zebrafish
(danRer10)
chr6:28079575-28079662 
ALTERNATIVE
DreINT0014986
(MYO7B (1 of 2))
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
No suggested primer sequences

				
R: 
No suggested primer sequences

				
Band lengths: 

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






Retrieved from "https://vastdb.crg.eu/wiki/Special:VastDB"