HsaINT0108954 @ hg19
Intron Retention
Gene
ENSG00000169994 | MYO7B
Description
myosin VIIB [Source:HGNC Symbol;Acc:7607]
Coordinates
chr2:128342353-128346130:+
Coord C1 exon
chr2:128342353-128342488
Coord A exon
chr2:128342489-128345966
Coord C2 exon
chr2:128345967-128346130
Length
3478 bp
Sequences
Splice sites
5' ss Seq
AAGGTGGGT
5' ss Score
8.23
3' ss Seq
TGGGCCCTGTGTCTCCACAGGCT
3' ss Score
11.1
Exon sequences
Seq C1 exon
GGGACAGATCTCACCATGCTGCAAAAGCTGAACAGCGTCCATGCCAACAACAAGGCCTTCCTACAGCCCAAGAACATCCACGATGCCAGATTTGGCATTGCCCATTTTGCCGGCGAGGTGTACTACCAAGCAGAAG
Seq A exon
GTGGGTGCAGCTCTCCTCTCATGTCCCTTCCAAATCTGGACCGGGTTCCAGGGAGACCGTGGAAAGCAGGCTCAGAGGATGAGGCTATTTTGCAGCTCTAGCAATGGGGCAGAGGGATGAGTAGTATGGCTTCTACTGGAGAAAGAAAATGGAGTGGACCGGGCATGTTTTGTTTTGTTTCTGGTAATAACTCTGTTGAGACATAATTCACATACCATGTTATTTACCTATTTTAAGTGTACGACTTGACTGTAATATATTCAGAGTATATTAATGATTGCCACAATTTTAGAACTTTTTCGCCACCCCTAAAAGAAACCCCTCATGAGCAACCACTCCCATTTCCCCCCAGCCCTGGGCAACAATTAATTTCTGTCTCTATGGATTTGCCTATTCTGACTTTTTGCATAAATGGAACCATATAATACGTGGTCTTCTGTGGCTGGTTTCTTTCACTTAGCATCATGTTTTCAAGGTTCATCTATGTTGTAGTACGTGTCAGTGCTCCATGTCTTTTTATTGCAGAAAAACATTCCATTATCTGGAATGTTTATCTCGTCATCAGTTGGCGGACATTTGGGTTTTTTCCACTTTTTGCCTATTATGAATAACACAGCTATGAACACCCATGTACAAGTGTTTGTGTGGGCATATGTTTTCATTTCCCCTGGGTATCTACCTAGCAGCAGAATTGCTGTGTCATATGATAACTCTATGTTTAACTGTTTGAGGAACCACCAGACTGTTTTCCAAAGCGGCTGTATGATTTTACATTCCCACTAGCAATGTATGAGGACTCCAGTTCCTCCACATCCTTGCCTACACATGTGATTGTCTGTCTTTGTTATTATAGCTACCCTAGTGGGTTTGAAGTCTCAATGTGATTTGCATCTGCATCCCCCGATGGCTAATGATGTTGATCGCCTTTTCATATGCTTCTTGGCCATTTGCACGTCTTCTTTGGAGGGATGTCTATTTAAATGCTCTGCCTGTGTTTTCACTGGGTTGTCTTTTCATTGTCGAGTTGTAAGACTTCTTTATATATTCTGGATACAAGTACCTAATAGGTGATTTTAAATTTTTTTCTCATTCTGTGGATTGTCTTTTCATCTGCTTGACGGTGTCCTTTGAGGCCCAAAAAGCTTTCATTTTGAAGAAGTCCAACTTATCTATTTTCCTTTCTTTGCTTGTGTCATATCTAAGAGTCCAGGGTCAAATACAAAGTCATGAAGATTTATCCCTATGTTTTCTTCTAAGATTTTTTTAGTGTTAGTTTTTACGTTAGGTCTTTGACCCATTTTGAGTTAATTTTGGGATATGTTGAGAGAGGATCGGTAATGGTTTTGACTGAAGAAGTGAAGGCCTGGGGTGGTCACCCTATGGGTGTGCCAAGAAAAACGAGGAAGGTGGCCGTGGGCTGCTGTGGTCAGGAAAGCAGGGCGGCCAGAGGGTCACTCTCTGCCCCTCATGTGGAGGAATGAGGAGGTGTTCTGGTCTATTTAACTGGAGACAGGAATCCAGGGATGATTCTTTTGAGTAGAGGGTGATCATTTAGTCAGAACAGGCTAGGCTTTGGGAGGCCAAGGGAGAAAGGGAAAGGTGCCGTGGCTCCTTCATAGTTCCTGCCACATCCTGGCTTTGGGCTCTTGGAAAAGGGAGAGGCTGGAGCCAGTCGGACCTGCAGGGTCCTGGGACGCAAAGAAGATACCGAGCCCATCCTCCATGGGGCAATTCAAGGCTGAGTTTTATTTTTTGAAATGATAGGAAACTTACATAATGCTAAGATTAAGGTCGATTCTTTCTAGACTTTCTGGTTGCAGAAATATTAATTAAAACTAAGCCTTCTTTTTATTTTGGATACCATGCTGTGCTGATGACCTCAGCTTTACTTACTCTGCCTGTTGGGAGACTGAACCCAGGAGTGTCTCAACCCTCCCCACCCTTAAAACATCCAGGGAGCTCCCTGCCCCTGGTGGGGAGCTCTGCCTGAGCCTCAGGGGTGCAAGGTGTCACCGAGTGTCCACCCCCTGCCCAGCACCCAGTGCAGCCCCCCTGGTGCTGCTCCCCTCACAGACACCTGCAGGAAGAGGTGGGAAACAGACTCCCTTCCCTCTCCCACTCTTGACTCTTCCTCCCCAGATCCACAGCAGGCTGTGCAGGTGTGCACAGAGCATACCACTAAAAGCTGGAGTGACTTAAGGGGAGGAAAGTGAAAGAGGAAAGTCAGGGTCGTGCCCTTGGGAGTTCGTCCTTAGAGACCAAGCAGTGCAGCCCCTGGCCTCATGGAGCCTGGCTTTGAGGAGCAGCTCATCTTCAGTGCCTTCTCAGTGTGGTTCTGTCCCTACTGCAGGGCTAGGCCATTCTTACTCATGGCCGGAGGGGAGACATGGGATCTTCTCACCCGCTGGAGCCATGCCTGTATTAGGCACTAGGGCAGCAGTAACAAACACCACAGACTGAGTGGCTTAAACAACAGAAATGATTGTCTCAGAGTTCTAGAGGCTGGAAGTCCAAGATCAAGGTGCTGGCAGGTTTGATCCCTTCTGAGGCCTCTCTCCTTTGTATGCAGATGGCCGTCTTCTCTCTGTGTCCTCATATGGCCTTCCTTCTCTCTGTGTGTGTCTGTGTCCTCATCTCCCCTTCTTTCTTTCTTTCTTTTTTTTTTTTTTTTTTGAGACAGAGTCTCACTGTGTCACCCAAGCTGGAGTGCAATAGTGTGATCTCAGCTCACTGCAACCTCTGCCTCCGGGCTTCAAGCGATTCTCCTGCCTCAGGCTCCTGAGTAGCTGGGATTACAGGCACATGCCACCATGCCTGGCTAACTTTTGTATTTTTAGTAGAGACAGGGTTTCACCATGTTGGTCAGGCTGGTCTCGAACTCCTGACCTTGTGATCCACCTGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACCACACCCAGCCTCATCTCCCCTTCTTATAATGACACTAGTTACACTGGATTAGGGCCCATCCTAATGACCTCATTTTACTTTAATCCCCTCCTTAAAGGCCCTATGTCCACACACAGTCATGTTCTGATGTATAGGGTGTTAGGACACCAACATATGAATTTTAGGGGACACATTTTAGCCCATGACACTGCCCCTCTCCTATTTCTGGAGGCTGCATCTGTTTTTAGTCTGAAGGAGCCTTAGCCCTAGTAGGATCTGCCCAGAGGCAGGAGGATGTGGCAGCTTATATAAGGGGGTTTGGAGTGGGAATGGGAATTAGGGGGGGTCCAGAGTTTAGACAGGAGAAGTGACTTTGTGCTGGGTAGATGGTGGGGGCCATGCCTGGGTAGAGGGGTGGAGAGCATGGCCGTAGTGGGGCCATTGTAGGAGGGGGCTCCTCCACGCATCCTGTATTCCCCCACACTGCCCTCTTCTTCCCCATGGGTGGGCAGTGATGGCTAAGCTGGGATGCTGGGTGGGCCCTGTGTCTCCACAG
Seq C2 exon
GCTTCCTGGAGAAGAACCGAGACGTGCTGAGCACAGATATCCTCACCCTGGTTTACTCCTCCAAAAACAAGTTTCTGAGGGAGATATTCAACTTGGAGTTAGCAGAGACCAAGCTGGGCCATGGGACCATCCGCCAGGCAAAGGCAGGAAACCATCTCTTCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000169994-MYO7B:NM_001080527:14
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.018
Domain overlap (PFAM):
C1:
PF0006316=Myosin_head=FE(6.6=100)
A:
NA
C2:
PF0006316=Myosin_head=FE(7.9=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)