MmuINT0104620 @ mm9
Intron Retention
Gene
ENSMUSG00000024388 | Myo7b
Description
myosin VIIB [Source:MGI Symbol;Acc:MGI:107709]
Coordinates
chr18:32122320-32124147:-
Coord C1 exon
chr18:32124042-32124147
Coord A exon
chr18:32122434-32124041
Coord C2 exon
chr18:32122320-32122433
Length
1608 bp
Sequences
Splice sites
5' ss Seq
AAGGTGGGT
5' ss Score
8.23
3' ss Seq
CGTGCTTCCTTTCTGTACAGTCC
3' ss Score
9.39
Exon sequences
Seq C1 exon
GGTGGGACCTCGGAAGCAGCCCCCACATGATGTAGAGGTGAAAGCGGCTGAGCAGAATGTCTCCAAATTACACCATGAGGTCTACCTCCCCAATGACACCAGCAAG
Seq A exon
GTGGGTGCTCCCCACAGTGAGTCTCGGGCCTCAGGAGGCTGCAGGGCACCTTCTTAGCATCCCAGCATGCTCTTCTCTCATTTCACTAGATCCACAGTCCAGGTTCCAAATGGACCCCCCATTGCTGCTGCTCCCATCTGTGCCATGGCATTTTTGCCTCCACACTACAAGCCAGTGTCAGGGAGCGCTGCACCAAGTTAAGGGACACCAGTGAGATTAGAAGTGGAAACTCTTTCAAAGGCACGAGTTAAGATCCCAAGCCAAGGAGGAAAAAGAGAAGAAGCCAGAGGGGTGGGCAGCAAGGCTGAGCCTTAGGGCTTGTGGGCCCCTGTAGACATCTGTGATGAGCAGCAGCCACTGCCCTGTGGTCCAGAGCTTGCCCTGGAGAATTGGGCTGGCAGAAGGGACAGGTAGGAGGTAGGAAACCACTGGGCCCTAGGTGTGATAAAGAAGCATCAAATGAAAATGAGACCAAGGCCACCCTCACACCCTCCCTCAGGGCTCCTTGAGCATCTGTGACTTGGGTGTACTTGAGCACCTTGTCTGGCTACAGGGTCACAATGTAAGTCCAAAGGTCCAGACCTCCTGGGTCTAGCCTGGGCATGGACAATATGTGCTGTTGCCAAGCAACGTTATATGTGGATGACTCTCTGGGGCCTGTCCTTCTCCAGACAGAACATAGCCAGCCCAAGGCTTATGGTGACAAAAATAGGCCCAGGGTGATGGTTCTGTCAGTAAAGTGCCAGCCGAGTAAACACAAGGACTTGGCCCTTACACAAGCGCTGGACTCAGTGGCACTAGGGAGGCAGAGACTCCCTGGAGCTTATTGGTCAGTCATCCCAGTCAAATGGATGAATTCCACATTCAGTGAGAAACCCCGTCTAAAAAAAAACATTTGAGAGCAATTAAGAAAACACTTGAGTCCCTTTAATCCCAGAACTTGGGAGGCAGAGGCAGGTGAATCTGAGTTCTAGGATAGCCTGGTCTATAAAGTGAGTTCTAGGATAGCCAGGGGTACACATAGTAACTCTTAACGAGAGAGGGGGGGGGAGGAAGGAGGAGGAAGAGGAGGAGGGGAGGGAGGGAGGGAGGGAGGGAGGATGGACAAGAGAAGAGGAGAGAAGAGAAGAGAAGAGAATAAAGACAAAGAAAGAAAAACGACAGACACTTGAGGTTTACCCCTGGCCTTCATATCCATGTGTGCAAAAATTCACATGAGCCAGGTGGTGGTGGCACACGCCTTTAATCCCAGCACTTGGGAGGCAGAGACTCCCTGGAGTTTATTGGTCAGTCATCCCAGTCAAATGGATGAATTCCACATTCAGTGAGAAACCCCATCTTAAAAAAAAACATTTGAGAGCAATTAAGAAAACACTTGAGTCCCTTTAATCCCAGAACTTGGGAGGCAGAGGCGGATTTCTGAGTTCCAGGACAGCCAGGACTATACGGAAAAACCCTGTCACAGAAAAAAAAAAAAAAAAATTCACATGAACATGGATATACCATACACACACACAAAATATAGGGTGAATAGACCTCAGAATAGTGGCTTGGGAAGCCTCCTTCCCATGCTAGGTCCTGGGCCTCACGTGCTTCCTTTCTGTACAG
Seq C2 exon
TCCATGGAAGTGGGCAGCAGTAGTCGGGTGAGAGACCTATGTGAGGGCATAGGCACCAGGCTCCAGCTGGCCTCCTGGGATGGCTGCAGCCTCTTCATCAAGATCACAGACAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000024388-Myo7b:NM_032394:39
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.278 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0078412=MyTH4=PD(15.9=47.2),PF093795=FERM_N=PU(8.5=22.2)
A:
NA
C2:
PF093795=FERM_N=FE(39.4=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGTGGGACCTCGGAAGCAG
R:
TGTGATCTTGATGAAGAGGCTGC
Band lengths:
214-1822
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types
Other AS DBs: