Special

MmuINT0130088 @ mm9

Intron Retention

Gene
ENSMUSG00000030359 | Pzp
Description
pregnancy zone protein [Source:MGI Symbol;Acc:MGI:87854]
Coordinates
chr6:128441183-128441690:-
Coord C1 exon
chr6:128441514-128441690
Coord A exon
chr6:128441274-128441513
Coord C2 exon
chr6:128441183-128441273
Length
240 bp
Sequences
Splice sites
5' ss Seq
GTGGTAAGC
5' ss Score
8.15
3' ss Seq
GACTGAAATTCCCTCTCCAGGGT
3' ss Score
7.84
Exon sequences
Seq C1 exon
GTGATATACTGGGCTCTGCAATGCAAAACCTCCAGAATCTTCTCCAGATGCCCTATGGCTGTGGGGAACAAAACATGGTCCTTTTTGTCCCTAACATCTATGTTCTGAACTATCTGAACGAGACACAGCAGCTGACAGAGGCGATCAAGTCCAAAGCCATTAACTACCTCATCAGTG
Seq A exon
GTAAGCAACTTTACCAACATTTCCCAGTGCCTTCTTCTTGGTTAAGATTTGGTCATTATTGTTGCTGTATTTCCAATCAAATGACCCTCCTGAGGATAAGGAGTCTCAATAGTGTCCATAACCTTAGAAGGATGTGATTAAAACATCTTTACTCAATGGTTCTTTTATAGGGTTAAGACAAACAAATAATAATTGACTAATGTCGCTGCAGTTCATACATGACTGAAATTCCCTCTCCAG
Seq C2 exon
GGTACCAGAGGCAGCTGAACTATCAGCACAGTGATGGCTCGTACAGCACATTCGGGAACCATGGTGGTGGCAACACTCCGGGAAATACTTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000030359-Pzp:NM_007376:24
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact





	

	
ORF disruption upon sequence inclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=NA C2=0.161
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF105694=Thiol-ester_cl=WD(100=51.7),PF076789=A2M_comp=PU(0.4=1.7)

							
A:
NA

							
C2:
PF076789=A2M_comp=FE(11.4=100)

						

					

				








    
Main Inclusion Isoform:
NA





     
                   









    
Main Skipping Isoform:
ENSMUSP00000032510





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
ENSMUSP00000107760
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
No conservation detected
Human
(hg19)
chr12:9388571-9388860 
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
chr5:101256776-101257066 
LOW PSI
BtaINT0007456
([1])
Chicken
(galGal4)
chr1:75785125-75785628 
GgaINT0112593
(OVST)
Chicken
(galGal3)
chr1:79427609-79428112 
GgaINT0112593
(A2M)
Zebrafish
(danRer10)
chr15:17969609-17970373 
LOW PSI
DreINT0140006
(si:ch211-285j16.4)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
GTGATATACTGGGCTCTGCAA

				
R: 
CAAGTATTTCCCGGAGTGTTGC

				
Band lengths: 
268-508

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






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