Special

MmuINT0156864 @ mm9

Intron Retention

Gene
ENSMUSG00000053580 | Tanc2
Description
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 [Source:MGI Symbol;Acc:MGI:2444121]
Coordinates
chr11:105757782-105761183:+
Coord C1 exon
chr11:105757782-105758018
Coord A exon
chr11:105758019-105760997
Coord C2 exon
chr11:105760998-105761183
Length
2979 bp
Sequences
Splice sites
5' ss Seq
AAGGTAGCC
5' ss Score
7.58
3' ss Seq
TCTCTATTTTCTTCCCATAGGTG
3' ss Score
12.79
Exon sequences
Seq C1 exon
GTCAGCAGACTGCTGATTCTGGGAGGTGCCAATATTAATTACCGGACAGAGGTTCTAAATAATGCTCCTATCCTATGTGTCCAGTCTCACCTTGGATACACAGAAATGGTGGCCCTGCTTTTGGAGTTTGGGGCTAATGTGGATGCCTCTTCTGAGAGTGGCCTGACTCCCCTGGGGTATGCTGCAGCAGCAGGGTTCCTGAGCATCGTGGTGTTGCTGTGCAAGAAACGGGCCAAG
Seq A exon
GTAGCCACTGCTTACTCCTGCTGCTTTTCTTCTTCTCTTTCTCTTGCCTCCCAATGTAGTATTCTAACTCATTTGTTACCTTGACGATCTAGCTGCACCCAACCCAGATGCAGAGCAGATACAAGGGAAGACCCACTGAGCCCATATCCTAGAGTTAGCCTGCTGCATCAGGATACAATTTTAAAATCTTTGAGAGGCACCCGTAAAACAACATTTGTCAACAACCACAAAAATTCCTACCTAATAACCCAGAAGTTATCTACTAAACACAGAAGAAGACAAACAAAAATCTAGAAAAGAAGCAAGAGCCAAAGAGACTGCAGTGAGAGGTCTGAACTGAACAGCGCTCCCTCAGACTTTCATGTTTAAAAAGAAACCTTAGGCACGGAGATGAAAAAGTTCCTTGAGATTTGGAGAAAAATGCACTCAGACTGACCAAGGGCACCCTACATGTTTATTAGCACAGTTCAGTTCTCTGAAAGCATTTCCAAATGTTTTATTGCTTTTGATGTGGTGTTAGGGAATGCATGCATATGAATGTATAGGTGCATGTACACAGGTGCACAAATGTAGAAACCGACTGGAGCAGGATGCTGGTGCTGTCTTCTAACTTTCTCCTTACTTTCTTGCCTTAAGAAGAAATCTCTCATTGAACCAGGAGCTTCACTTTCCAGCTGTGCTGGCTGGCTAGTGAGCTCCCAGGATCCTCTGTCTCTGCCCATAGGCACTGGTGTGACAGGCACATGTCATGTCCTGTTTTCATGTGGATGTAGGGATCAAGCTCGGGCTCTTGTGGCTACAGAGCAGGCAGTCTTCCTAGTGAGCCCTCACTCCAGCCTCCAAAATATTTTCTTTATAGTGTTTTCCAAGTCACTGATACAGGGTAATTTAATTTCAAAATACTAGTAAAAGAAAAACCACTGGCTTCACAAATGTAGGCCACCAAGGAAAAATTGTAGCCTCGTGGTATTTTGATTCTGTCATGAAAACTAAGAATCACACAGGGAAATCTAAGTAATATATGGGACCTCATTTTGAGATGTTCAGTATTATCACCAGGGAAGCAAGGAAAACTCCTAAGACTCCTCACTCCTTGAGGAAGTGAGACCTGGGTTCTCAGCAGAATCACAGAGCCTTAGATGCCATTGTGACACAGATGGCCCACCTATATCAATGTCTCCTTTGATTGAATAGATGCTCCTAGTAACAGCCTATCTGGTCCTGATAGTACTCTTGATGTAATTTACATCCAACTGGGTCCTTGAATCATCTCTGCCCTATACCACCATGCCACTTTTTTTTACTTGTTTTTCATTGTTTTCCCAGAGCAGATGGTTACACTGTTTATTCTTTTCAAAATCCTATCACATCTCTTCTGTATTTTGTATTAGTAAGATTAAGCTAGGGGTTGGCGAGATGGCTCAGTGGGTAAGAACACCGACTGCTCTTCTGAAGGTCCAGAGTTCAAATCCCAGCAACCACATGGTGGCTCACAACCATCCATAACAAGATGATGCCCTCTTCTGGAGTGTCTGAAGATAGCTACAGTGTGCTTACATATAATAAATAAATAAATAAATAAATAAATAAATAAATAAATAAATAAAATCTTTAAAAAAAAAAAAAAAAAAAAGATTAAGCTAAAAACAAGATGTGGAACCTGGCATGGTGGTGCACAACCAAAAAACCCAGCCGTGGGGAGGCATAGGCAGGTGGATCTGCATGAGTTTAGGCCATTCTAGTCTATAAAGCCAGTTCTAGGACAGCCAGAACTATATAGAGAAACCCTGAAGAGTCAGGGGGTACACATCTGTAACTCCATGACTTGGGAGACTGAGGCAAGAGACTCACAAGTTTAAAGTCAGCCTGGGATATACAGGAAGGCCCTCAAAAAAAAAGGAGGAGGAAGAGGAGGATAAAGGAAGTGTCTATCTCAGGGAACGTCTGTCATAGAACAGTGTTCTTTGCCACACTGGCCTATGCTCCTGCCTAACAAGGAAGCACTTGATTTTCTTTCAGCATTTCTTCTACCTGTGCTCTTGGTCCTGGTCTGTTGCTCTTTATTTCACTTGTTATTTCTTTTCTCTTCTTAATTCACATCACCCTTTTCCAAATATTTGTAGGTTTATAAATATTTACTTTATCTGATTGACCTTAAAAAGAAAGTCTTCTCACCTGCTTACCAGAAGCTACAGCTCATCCCTTCACATCCCTCAGACCCATCCTCAGCCACCTCTCTTCCTCACTCTCTGTCACTACTCATAATCCAGCTTCTGGGAGTTAGTTATTATATAAATAGAACTTTTACTCACCAGATGTAATTGTTATCTAGGACGCTTACCGATAAATACACTCAATCTTTCTAGTTCTTTCTGAACTCTGGCTAGCTGGTTCAACTTGGCTATTGAGGTAGCCCAAACTCCTCTCCAAACTGATTGATTCAAATTGGCTTCTCTCACTTTCTGACTGAATTGCTCTGCTTGGAAAGATTCCCTCTGAACTCCACAAAATGAACTGCCCCAAACTCAACTCAACTCAAGTCCTCTGAATTGGCACATTCTTTCTCCCTCACTGCTCCTAAGTAGCCTCTCTTTCCTGTCTGTTCTCGTGAGAGTTGGGCAGATCCTATCTATGACTCATTCTGTCAAGTCTTCCTCTGACTTGTTACTTTGTCTTCTCCTCTTAGACATTTCAAACATGCCTGCTTTCTACAAACTAAATTCACCTATATTGTTTGGGATAAAAGGTGTGTGTACTAAGGGTGTGTCTGTATTCCACCAAGGTCATTCTGTAATCCAGAGTGTGTCTGCATTCCAACCAAATCACCTGAGGGTTTTGTTTTTTTCTTTGAATGTAAAAACAAAAGCCTTGCCTCATTTTCTGGGGAAAGTTCTCTGCAGAGGGATGTACAGAGGAACTGGACATCAATAATCTAGGCTGAGTTCCTTGTTCACAGCTCTCTCTATTTTCTTCCCATAG
Seq C2 exon
GTGGATCACTTGGATAAGAATGGACAGTGTGCTTTGGTTCATGCTGCTCTGCGAGGTCATCTAGAGGTTGTCAAGTTTCTGATTCAGTGTGACTGGACAATGGCTGGCCAGCAGCAAGGAGTGTTTAAGAAGAGCCACGCCATCCAGCAGGCCCTCATTGCTGCAGCCAGCATGGGTTACACTGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000053580-Tanc2:NM_181071:16
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact





	

	
ORF disruption upon sequence inclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.000 A=NA C2=0.000
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF127962=Ank_2=PU(58.7=68.4)

							
A:
NA

							
C2:
PF127962=Ank_2=PD(39.1=58.1),PF136371=Ank_4=PU(20.6=21.0)

						

					

				








    
Main Inclusion Isoform:
NA





     
                   









    
Main Skipping Isoform:
ENSMUSP00000069312





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
ENSMUSP00000086912, ENSMUSP00000097904, ENSMUSP00000123674
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr17:63389545-63395742 
ALTERNATIVE
HsaINT0163629
(TANC2)
Human
(hg19)
chr17:61466906-61473103 
ALTERNATIVE
HsaINT0163629
(TANC2)
Rat
(rn6)
chr10:94094190-94102878 
LOW PSI
RnoINT0147541
(Tanc2)
Cow
(bosTau6)
chr19:48376284-48379569 
LOW PSI
BtaINT0145020
(TANC2)
Chicken
(galGal4)
chr27:2608236-2610180 
LOW PSI
GgaINT0143985
([1])
Chicken
(galGal3)
chr27:2525588-2527532 
LOW PSI
GgaINT0143985
(TANC2)
Zebrafish
(danRer10)
chr3:22661549-22661635 
LOW PSI
DreINT0160163
(tanc2a)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
No suggested primer sequences

				
R: 
No suggested primer sequences

				
Band lengths: 

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






Retrieved from "https://vastdb.crg.eu/wiki/Special:VastDB"