Special

MmuINT0157278 @ mm9

Intron Retention

Gene
ENSMUSG00000029192 | Tbc1d14
Description
TBC1 domain family, member 14 [Source:MGI Symbol;Acc:MGI:1098708]
Coordinates
chr5:36863093-36865658:-
Coord C1 exon
chr5:36865576-36865658
Coord A exon
chr5:36863211-36865575
Coord C2 exon
chr5:36863093-36863210
Length
2365 bp
Sequences
Splice sites
5' ss Seq
GAGGTACTG
5' ss Score
7.67
3' ss Seq
CTTTTAATCACAATTTACAGAGC
3' ss Score
5.78
Exon sequences
Seq C1 exon
AAATCTCCCAGCCAAGCCAGCTGAAGAAGCTCAAAAGCACAGACAGCAGTATGAAGAGATGGTGCTGCAGGCCAAGAAACGAG
Seq A exon
GTACTGTGGCAGCCAGCCAGCTCTGGTCGCCTCTACTCTGCTAAAGTTCATTAGCTTTAACCTTGCAAAGGCATTCATACTTTAGAATATATGACTTTTCCACTAAACAGACAAGAAAGGATGTGTCTCATTATTCCTGGAAGCATAATGACCCTACATAAGAAGAGCGAGCTGTAGTAGCACACACCTGCTAACTTAGCACTTGGGAAGCTGAGGCAGGAGACTCAGGAGTTCAAAGCCAGTCTTTACTATATAACAAGATGCTGTGACAGAGAACATAGATTTACATGAGAAAAGATGTGTGTGTTAGAAAGAGTGGCAGCTGAGCCTGTGTGGTGTGGCGCACGCCTTTAATCCCAGCACGCGGGAGGCAGAGGCAGGGGGATTTCTGAGTTCGAGGCCAGCCTGGTCTACAAAGTGAGTTCCAGGACAGCCAGGGATACACAGAAAAACCCTGTCTCGAAACAAACAAACAAACAAACAAACAACAAAAAACAACAAAAAAAGAAAGAGTGGCAGCCAATAGTGACATGCAGCTCTTTCCCCTCCTTGGCTCTTTCTCCCCTTCTTAAGATGTGAGGGATTAGATATGTTCTATGCAGCGTTTAAAAAGCTAGAGAGTGCTGTGACGCTGGAGTGTTTTAAAGTAAATACAGTAAGTACATGGAATATCATTCACCCTGTAAGAAGGAAATTCTGACACATTACAAAATTGTTGAACCTGATTGGTCCAAAGTGAAACAAGCCAGTAACTAAATGACAGACAGTATGATGTCATTTCTTTGGGGTGTGAGAGTCTTTTCAGCAGAGGACTACCTGAGGAGGGGCAGACAGGGAGTTAGTGGTTAATGAGGACCAGTTTAGTCAAGGAAAAGACAAGGAGGTTCGAGATAGGATAGTGGTGGGAGTGTATCACAGTAAGAATAAATGTTACAAGGTTATACAGTGAAAATGGTTAAAATAGTAAACTCTGTGTTATGTCTCTCCATTAAAAAAAACTATACCTGTTCCCAAGGATTCATGAGTAGATGGTTCCAGAAGCTCTTGCTGCTCCAGGATCTAAAGAGGCCCAAGGCTTGTGTATAAAATTGTTTACTCAGTATGCATATAAGCTATGTACACCGTCCTGTACTCAGGTCATCTCTGGATTACCCACAGTAGTTATGTGCCACATAGACACTTAACAGAGGATTGCTCAGGGAAGAATGGCATGAAAACAGTGTGTACATGTTTGGTACAGACGTGATTTGGTTGGCTGAGAGAGCCCACGGATGTAGACTTACCGTGGAGTAAACTGAGGGAAAGATGTGCTTAGTCTGCCTCAGCACTGCTGCTGGTAAATGAAGAGTGAAGCATATGGGGCTGGAGCCGTGGCTGGGTGCCGGAAAGCACTTGTTCTTGCAGGGGACCCGAGCTCGGTTCCCAACACACACTTGATAACTCACAACCCTCTTTAATTCAGTTCCAGGGGTTTGTTGATGCCTTCTTTAGACCTCTGAGGGTATCAGGCATGTACATGATACACAAGTATACATGCAGGTAAAATACTGTACACATAAAATTAAAGAGTACTGCACAAGATGTTAGGAGTGCATTCAGGGTTACATTAGGAAGAGTGGGATAGAGAATACATTGGGCTTTCAGTGTTCTGTGATGAATTCTGTTGGTTTGGTTGGATACTTTCATAGGCTTTGTTTGGTGTGTTGTATTCATTGAATTATATTTGTGATTTTATACTGTTTTAAAAGAGCAAGCTATACTTAAAGCTTTTACTGAAGGGTGGATAGAATGTTCTGTAGTCTATGAGGAGTAGGGTGTGATGCATATACCTGTAGTCTCAGCACTCTGGGGTAAGAGGAAAATACTAAGTTTGAGGCCAAACTGAACTACATAGCAAGACCCCAAGTTCCCACAGTAAATCCATAGGTTATGAAGTGAGTGTCAAGAGCAGACATTTGCTGCCTACTCACACCATCCATCTGTCTCTATCTATCACTCTCCCTCTCTCCCTGCTCCCAACCCCCTGTGTATGTGTACTCTCACAAACATGCACTCAGGCTAGAGGGGGCATCCATCAGGTGTCCTGTCGCTGTCCATCTTACTCTTGCTGACCTTGAACCTGGTGGATTTTGCTGGACTGGCAGTCCGCAATCCTCCTGTCTACCCTGCTCAGTGTTGGGGGCTTACAGGCAAGCACTCATACTCAGCCTTTACGGGGGTGCTGAGATCTGAACCCCAGCCCCATGCTTTTGCAGCAAACACTCAACTACTAAGTCCCATCTCCAACTCGTCCTTCTCTGCTATTTTTCTGGCATGGTGAGTACTGGCTGCTCAGCGTTTTCTTTCTTTTAATCACAATTTACAG
Seq C2 exon
AGCTTAAAGAAGCCCAGCGTCGGAGGAAGCAGCTGGAGGAAAGGTGCAAGGTTGAAGAGAGCATTGGGAACGCTGTCCTCACCTGGAACAATGAGATCTTGCCTAACTGGGAAACCAT
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000029192-Tbc1d14:NM_133910:5
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact





	

	
ORF disruption upon sequence inclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.717 A=NA C2=0.189
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF085986=Sds3=FE(31.1=100)

							
A:
NA

							
C2:
PF085986=Sds3=PD(40.0=90.0)

						

					

				








    
Main Inclusion Isoform:
NA





     
                   









    
Main Skipping Isoform:
ENSMUSP00000116519





     
      









    
Other Inclusion Isoforms:
NA
          









    
Other Skipping Isoforms:
ENSMUSP00000031094, ENSMUSP00000084830, ENSMUSP00000098830, ENSMUSP00000114508, ENSMUSP00000115467, ENSMUSP00000115926, ENSMUSP00000116519f2543A, ENSMUSP00000117414, ENSMUSP00000119347, ENSMUSP00000121516, ENSMUSP00000121816, ENSMUSP00000131876
  



Associated events






Other assemblies


mm10




Conservation


Human
(hg38)
chr4:6996408-6999084 
LOW PSI
HsaINT0164007
(TBC1D14)
Human
(hg19)
chr4:6998135-7000811 
LOW PSI
HsaINT0164007
(TBC1D14)
Rat
(rn6)
chr14:79409713-79412226 
ALTERNATIVE
RnoINT0147944
(Tbc1d14)
Cow
(bosTau6)
chr6:118278505-118279816 
LOW PSI
BtaINT0145425
(TBC1D14)
Chicken
(galGal4)
chr4:79482890-79484478 
ALTERNATIVE
GgaINT0069292
(TBC1D14)
Chicken
(galGal3)
chr4:82876179-82877767 
LOW PSI
GgaINT0069292
(TBC1D14)
Zebrafish
(danRer10)
chr7:39422297-39422658 
LOW PSI
DreINT0160569
(tbc1d14)
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
No suggested primer sequences

				
R: 
No suggested primer sequences

				
Band lengths: 

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Pre-implantation embryo development
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types






Retrieved from "https://vastdb.crg.eu/wiki/Special:VastDB"