MmuINT1022892 @ mm10
Intron Retention
Gene
ENSMUSG00000039842 | Mcph1
Description
microcephaly, primary autosomal recessive 1 [Source:MGI Symbol;Acc:MGI:2443308]
Coordinates
chr8:18631516-18641665:+
Coord C1 exon
chr8:18631516-18632643
Coord A exon
chr8:18632644-18641564
Coord C2 exon
chr8:18641565-18641665
Length
8921 bp
Sequences
Splice sites
5' ss Seq
AAAGTATGT
5' ss Score
6.93
3' ss Seq
CCACTCTACTTGTTCTTTAGGTG
3' ss Score
9.39
Exon sequences
Seq C1 exon
ATGAATCCTTTGCCAGTGGCTCCCACTCATCTTTCGGTGATTCCTGTGGAGATCAAGAAAGGAAACTGGGAAGATCTGCTAATGAGATGACCACGGTGACATGCCCTTCCTCACCTGTGTTGAGGGCAAGCAGTTTTTATGGCTCAGCATCACCCAACCATCTCAGGCAGCCACGTCCTCAGAAAGCTCCAGACAGTCCTTCAAAGGAGAGCATCAACTGTCAGAAGGATGCTACAGGTGCGGTAGCTGATTCCGAGAGAAAGCAAGCTGCAGGTGTATCTCAGGGGGTGCCTGATGAGAAGCTCTGTCTGTCTCCTACGATGTCCATCATAGAAGAACACCAAGTACGGTTGGGACCCAAGAATTCTTCTGCAAAGAGAAAAAGGGCAGCGGACTTGGGTTCATCTCCAAAAGGAAAACTGAAGAAGAGGTACAAGAGAAAGTCTGCTCTGGCAATACAGTTATTCAAGTCCGACCAGAGCCCGCCGTCCACAATCAGACTCATTCCGGGAACTCCTGACGTTGAGGCTTCTTCCTATGAGGACTATTTTTCCCCTGATAATCTCAAGGAGAGGAATTCGGAGAGACTTCCTCCTGAGGCTCAGCAACTAGCAAGCCCTTCTCTGTTCCACTGCAGAGGTCTCTCAAAGTGGGAGCGAAGAAACATGCTGGAAATGTGTGATTTTACCTGCATTGGTGAAAAGCACAGATCCATCAGCAGCATTAGTGACTTAATTTCAAAAAGTGCCTCTAGTCTTGAGAAACCTGTCAAGGAGGAAGTGAATACAGCTTCTACCTGCTTGCTTTTGGTGGAGACCTCTGCTAACGACAGCCCAGGGCTTTGCAGTCAGCCTGGCCCTCAGCTGAGGGATGACACAGGCCCAGAGGGAAGCAGCCACCCTGACACCCTGTCTAGTTCTGCCCACCACATCACACCCTTGAAAGGAAATAGTACAGAAACCAGAGACCCAGGTGATGGAAAAGGCTCCCCCAAAGAAGGTAGCACGCCTCCTGCATCAGCCTCTCCTGAAGATGAAGTACACATCTGTAATCTCAGTTTGGGAGAGGATTGTAATGTAGAAAAGTCTGTAGAAGAAAAGGAGAACATAGCCACAGGATATAGTGAAA
Seq A exon
GTATGTGAGCCTCATTTCCCAAGTATTGTTTGTTCTGCCAGTGTGTAATACTGTGCTCGTATTTTAAATCTGTCCTTAATCTTTATAATTTAAGTCCTTCCCCCTCTCCTTTTATTTTAAGGAATTGATATTTCCAATGATGCTCTTGAGGGATAGGTGGGAGGCCCTGACCTGAACTTTGTAGTCAAATGTGTCACCATGAAAATACCTCCCCAGGCTTTGTCCTAGTGGATTAAAAGAAACAGTAGTGCTTACTTTAAACTGTTGACCTGTATACCTTTCCTATATGCCTCTCTCACTCAGCATGACTGCACCAGAGACATAACTGATAGAGGAATTTCTTTTCTTTTTATTTTTAATTTGAGTTTATTTAGTAAGGGTTTTAATGTGAGGAATGCAGTAAAGAAACCGCCAAAAGACCGCTCCATAACTAGGAAGGTTTTTCTTATGAATAAGAAAGTATCCAGAAGCATCTGGAATAGTCCAACACAGAGAGAAAGAGAACCAGACTGGCTGTGGCCATGGCGATCTGCCAGAGAAGAGAGATGAGCAAGAGGTGAAGAGTGCAATTCAAGAGTGGTGGGGAGCAAGGGAGCAAGAGATGCAGGGGGTGGGGGAGGAAGGGAGGGAGGGAGAGAACAAGAGAGCGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAAGCTGAGGCTAGCAGGAGTACCCAGGGCTGAGGGCTCTGAAGAGAGCTGGGATCTGAGGTTCAAAGGTTGCAGGTTGGAGGCTAGGGTGGAGGCTTGTATACTAAATGCTATCAATGAGGGAGCCTGGCGGCAGCATGGGCTTTGATACAGCCACAGATACATGTTAGTGTAGCCATATGTCCTTTCTGCTGCACATAAGAAAAGTGACTCCTTTTGGCTTGGGAACTATTTTCACAAGTTCCTGAGGAAGGCTGGCTTTTATCTATCCAGATTGAGTTGGGCGTAGACTCAATTTTGGGCCAAGTCAGAAGGCTTGCCCTGGTTGACGTAGGGAATGGGGTTGCCCGTTTGACCTGGCATGCTTCTACTGTAGAACTCTAGAGAGCATCAGCCATGATTTTGCTAACAGAAACTATGAAAAAGTTTTGAAATTTGTCATCACTGTTTACTTTGGGCACTGAAACTTTGGGCAATGTTAAATAAGAGCAAACATTAATTAAGACATTTTGCTCAATTAAAAATTTAGTTTTGGATCTCTCTCCAGCCCCCAAGTAACTCTGGTGTGGCTTTGATTTCTGCTTATTTTGTATCAAGACTACCATTCAAATAGGTTTGTTTATTCCAATCTGTAACTTAATTATAATTACTAAAGTGATTTATTTGTTGATCAACAAATAATAAGCTATATGATTATAGGGATTTAGGCAAAGATGGCAAAAATATCAACAGATTTTTGCAAAGTTGAACTCAGCCTTTGACCATTATTTAAGTTTGGCTAATATTAAATATGATCCAACTGACTCTTGATCAGTTCTACACTTGAGGTGGTTTCACCCACTGTGGCTAGGGCAGCTGTGTTGGGCTGAAATAATCACAGTTCTAGCTCTTTGAGAATAAACTCACCTAAATTGGCTCAGTACATCAATTAAATGATTTTTGGATTTTAAGCTGGTAAATAGCTTGGGTTTTGAATAATTTATATTATATTCATAATAGTATTGTTACATCTAGATTATTATGTGTTTTCAAAAATGTATAAAATTACATAGACTATAGTAAATATGAAAAAGTATAATGTTTTGACAGTTCAGAATATCCTGTCTTGTGTTTTGAGTTTTTATCTTTTTTACAAAGCACTTGAATATTATATGATATGTAAATATAATTTAAGTGGGGCAAACAGCCCGGCACACCCTAAACCCTAGCACTGCAGGTGTGCAGTCATTAGAAGAATGTGTGTTTCTTCATCCAGGGCTCAACCTTCCTGTCTTCAGTCCAGACCATTAGGCTTCAGAAACTGCATGAAGGGCATGGGCATTGGGTGGCACTCCAGTACTCAGAGGACACTGGGAAATGTGCTGATTGTGAAGTGGGCCGGCTTGCTGGGACACAGGCAGGGGTGGGTGTGACTAAGTTTGACTCTGATGGAAATATTCTGTAAATTATCACGTCACTACCACAAGACAACATGGGCTCCTAAGACATGAAAACCCCTCTCTAGCCTAAATCTAAGCACTTTTTTATACTTAGTAACATTAAGAAGACTCACGAATATTTTATATTGTCCACTATCAGCCCAATCTGGATTTGGGACAATCAACTCTTTGGAGATCCATCCTAGATACAACCATAAATCCTTGGGCTGAAACGGAAATTCCATACTTGCCCCAAATAGAGCCAGGAAGGCTGCTCTGAGCATCAGCTACACAGACCCTCTATCCTTCTTGTTGACATGAAGGGCTATTCAGTGCCATTCCACCCCACTTAAGCTTGCTGACTCTAAGATAGTGTGCAATGAGGCTTCTAAAGAAAGCAACCAAGAAGTCAGTGGCTGATCTTGAAACAGTGGGGTATAATCATTAACTCTTCACATTTTTATTCAATACTTTTATGAACAATTTAACAAGAAGTTTCCTTTGTTAGAAAGAATAAACCTTTCCACCTCAATTTCTCACTTTCTGCCTGTGTTAATTCTCGAATTCCTATTAAAGGATAGTGGTAGACATGCTGCGCCTCACATCTGTTTCTACTTCGTAAAAAGAGAGCTGAAGGAATCAGTATGCACCCCTGCCCCCAACAGGTTCTGAGGTCCTTGAAGAAGCCAGATGATAAAGGCAGATAGAACACGGCGTCAACTGGTGGGTGTATTTCAGGGAGCACAGGCGTGAGAGAGAACAGCCAGAGCTGGGGAAGAAGGAGAGTAGAAGTGAGAGATAATAGAATGAGAGACTAGGAAGAGAGTGTAAAAAGAGTCAGAGAGAGTAGTGAGACTAGCTGAGAAGGAGGAGTAAAACTCGGTTATAAAGAGGACCGATGTTATCTGGAAAAAGTGAAGCCCAGGGAAGGGTGAAGGTCTGTGGTGCTAGTGTGGACTTCAGAATGTCTAACTGGTGGCACTGAGGGAGCCTGGTGCCAGCACGGGCTTTTATGCAGCTGCAGGTACATGTCAGTGGAGCCATGTGTCCCTTCTGCCAGACAGAAGGGAAAAGATTCCTTTTGGCAGGTGAAACCAGTGTCAGAAGTTCCTGAGGAATTCCGGCTTTTATCCAACCCTCAGAAATCCTCTTGTAGTTCAGGCAGTGCTCATTTCTGACTAGATAGACTACCTTTTGGAGTTTGAGGAGTTGAAGCGTCCTTTGGTAAACAGTGATGCTGGAGAGTATAGGTGGCTCCACCAGGTACCCAGAAGGCTCCTCTGAGGAGGTTTTATGGACCTTAGGCCAGGTGAGAGGGTGTGCTTGTGTCTACTGGAGGTAAGTACAAATGGCCGAACATCCTGCAGGAAGGAGGAAGCCAGTGCAGCATCAAGCCATTGAGCCTGCGAGGTGAGGACAGTGACCACAGTGTGGCAGCAATCTGATCCTTGAGACCTTCCCTCCCCATCGAGACAGGGTGTTCCAGTTTGTTTTATAGTGTGATGAGAAGTTGCTGGGGATTCTGAGCTGGAGCAACGAAATCTGATTTGTTTTCACTGTAACCCTGGATACTCTGAAGAACAAACTGTGGCTTAGTGTGTTTGCTAGAAGCAATTACTGTCAACAACAGCCCTTCCAGATAACTATGGTGCATATAAACATGCAAATGAAATATATTTAAAGGGATTCTCTCATATGCATAGAACTGTATTATCCTGTTGCTTTAAATGGGTCTTTTAAAAACTCATAACAATATGTCAGATGCCCTGTTCATAGAAGATACTTGTTTCTTTTAGTATAATCTGTGTTGAAGATCAGTGGTATTTTCTGTAGTGGGTCAAAAGGATACAAATAGAGAGAAATATAGATAATTATAAAATACAGATAATTAGAGAAAAGACATTCTTGCAAAACTTTGATTGATAAAACACAAAATTGAGTATAGTCTTGGAATGCATGTCTGCTCTTGAGCAGATTTCTTGGGTGGGGAGAGAATGAGTGACCCTGTAATTTAACTGGAACTCCGACAGGTGAGTTCCCATCACCTAACCTGATTGCAAATAATTCTTTAAGGTTATTGTGGAAGGTGTTATGCATCTCACGCTTGAGGGCGCCTTTTCACAAACACTGGTCTTGTCCAAGTCTGATGCCAAGGGAATGATTTTCAGACTTATTGGGTCTTAAAGGTGGCATTTATGTAATTATAGGTTCCCTTGCCACAAGCATCTTCCAGCAGGTCCTGATCTTCTGCATGCATGACTTGGTGGTGAGAAGATAGGTGGGAGCTCTTGGATCATGCAGGGAAAGAGATCTTGCAGTTAGGCTATAGGTTTATTCTTTTATTAGGTCTGGGAAATGTTGTAGGAACTGTATGAAGTCTGAATTCAAAAAGAAATGTCTGCACCCAAGTTACGTGGAGATGGGTGGAGGTCTTGCTTTCTGTTTTAACGTATTTATTTTGGAAGCAAGATCTTACTGTGTAGCACACTTGGCCTCTACGCCGCTGTGACTGTGGGTATGTGGCAATACACCACGCTTCATTTATCTTTCGACGGTGCAAGGCAGGAGGTATGAGAAGCAGCTTGGTGAACATTGAGATGACACTCTTCCGCCTCTGCTCCTAACATGCAGTCCAGCTGAACCGCCCAGTAGATAAAGTTTGCCAGCCGTCCCGAGCACCGTGGTGTCTGATGCAGCTCCTACTGCCTGTCACTAGTGATGGTAACGCAGGAGCTCCGTATGTCTCATCTGAATACCAGCAGAGTTAGTACTTTCCGTGCTATACCCCACATCTGGCCAGATCAGATTCAATGCAGATCTGATCCTGTGCAGCGAGTGGTGGAATTTCACGTCAGCATTTTATACATGTGTGTTCAGTTACCTGCACATTTTGGCCACGTCCACTATTGGGTTCTTTTACAGTTACCAGCTGTTAGGAGTTGAATGATGGACCACTGTCCTTCCAGCAGATCTGGCTACCAGATCTTACAAAAGACAAATTGCAGATGCATACACATTTGTTGTTGAGCAAAATGGAGAAAGCCTTCCAAGTAGACAGATCTGCTGAAGACCTAGCCTGTGTCCCTTAACTTAGTTTCCTGTTTGGGGCAAGCCTCTATAAAAGTTAATGTGTGCCTCAGACTACCTAATATGTCTGTCTTTCATCATAGGTCATTTAGGATTCAAGATCTGGGCATCGTCCGCAGGGATACAAGCTTCAACTAATACCAGATGTTCATGCCCTGCTCTTGCATGGTTGTGGAGTGTTTTGTAATAATATTCCTGCCAACCCATTCTTGACTTCAAGAAGTTATCCAATGGGAAGCTTTCTGACAGCTTGAGGATATCAGTCACAGCTCATTTGCTTCATGCATCCTGGCTGGCAGTTAACAAGGCATTTCAAAACGGGCTTGTGCACTCACCTCCCAGGTGTAGCAGCTGGTAGCATAGGAGTGGATGACACCTGTGTTTTGATGGGGCCAAACATGTACCTTCTATGAGTCTATACTGAAGTATTCTAACAAAGAAACCGTCATTTCTGCCAAGTGTTTAATCCTAGTGTGTTAGTCTGATGGCAGTGACTGGAACTAGCTGGGCTGATCTTGGGAGGCTGGAGGGGTCACTGCCTGTAGCAGCTCTGGGCTTATCAGTACAATGAGGCTGTGACAGACAGGCCTTTCACGGGACCAGGGGCTCCTGTGATACAGGGAGTTAGTTACTGAGCCAGTAGGATATGCTGATAATGGTTGTATGGGAAGATCACAAGCTCAGGATCTTGTGGAATGTCTGTCTGTCTCTGCTCACACTTGTAACTTTTTGAGTTTTCTATCACTGTAAAAATGTTGGAGCTGGGGTTCTCACCTATGTGTTTTTGTTGAGACATCGTCTTGCTCTGCATCCTACCCTGACCTTGGAGCAGCTTTCCTACCTCAGCCTCTAAGGTGATGGAATTCTACTCCTGTCCCACAGTACCCTTCTGCTTGATCCTTTTTCTTTTTCTCTTTCTTCAGTTGCATTTGATTATTTTGTGGAAAGTAGGGCAACACAGCATGTATGCAGTGAGGCTAGCGAAAATGAGAGGCATCTAGGATTTACAGTGTGGATAGAACACTGTCTACCCCAACCAACCCCAACCCCAGGCCCCAACCCAGACCCTAGATGAGAGTGTTTGGAAATTGGGCCTTCGGAAGGAGGTTACATTCAGCTGAGATCTCAAGGCTGGGGACCTTATGATGTAACTGGTGTTTCATAAAGAGGGTAAGAAACACCAGGAATTCTAGTCTCCTTGCCTGTGTGAACAGGCCGGGGGTTGGGGAGAAGGCTCACCAGAAGCCAATTATCAGTGTCCAGTTAGGATCAACATCTTCGAAGTCTCTGGAACAAGAGATAAATCCTCCTTATCAAGAGACCCAGTTAAGTGTTTTAAGACATTCATCAGACTGTCGTATGGAGGAACAGCAGTTCACTGGAGCCCAACTGTGGGCAGGTGGCCAGGCTTCACCTAAGACACTCCAAATAGATACCTGTTAGTTGGTTGCATCTATCCATCCATAGACAGGGAAGGTACTTAGCAATGTAGGGATAGATGGTGTTATGGGACCTCATGGTGTCCGGGGTGGTGGGGCTGTTTGCACACTTGCAGCACAGATGTGACACTTGTGAAAGACAGGAGAGCCAGGGGAGGGTGCTGGGAGATGGGACCTGACTGGCCTTAGAGCAGCCTTGCATGGTAGAGCATGCGAGATGTGTTGAGAGCTATGTGCTTGCTTTATTCTGTGACTCGGGGGTCTTATGTCCCCTTATGAATATTCTATCCCTAAATCACTTCTAACCTCAGATCTGAAAGATGATTTAAAATGAGGCCTGTTAGAAGCAGAGAAGTTCTGTTTGTTTGTTTGTTTGTTTGTTTTTAAGATTGTTAAAAGCATTAGGAAGTAATTTAGAAAGTTGGTGTCACTTGCCAGGTGACAAAAACGTTTGCTACCTCTTAGAGTAGACTCTCACTAACCCTCTACCTGCTTGCTCCAGTCCATCATCCTCTTAAAGCCAACTGAGGGCTTCAGTGGGTGGGCAGTTATCTGAGATTGAGAGGGACATGACATTTAAAAGATGCCTGAAGAGGAAGGGGATTAATGTGTGGTTGGTTTGTCTCCAAAGGGATCCAGTTTAGACTTTTATAGGCAAAGAATGTTGACCTTAAAATGTTTATAGGGCCGAGGGTACAAATAACAGCTAGTTTGAATTCTGGAAAACACTTAACTATTATTCTGTGTTTTTTGAGTTCATGATTCATTTTTACACTTATTTATTGTGTACTGTGTGTATGCAAGGGTGTGTTGGGGGGGGGAGGCTGTGTCAGGACAAATCTTAGCAGTTCTCCCTGTACACCATGTACGGTTTGGGGGTAAGGCGCAGGATCCTCCACTCACTGAGCCATCTTGCTGACCCTGCTTTTATTTAGATACAATTCCGTTTTGAAGAAGTGTGACTCCTCAAACTTGGATCATTCTCAGCTTTATCACACTGCCCCACCATTTGCAAAGTAGACTTTCTCATGGTGTACACACTTTAGTTTCTGTAGGTGTTTTTATGATTTTGCCTTGGAGCATATTTATTTGCATGTCTAGCCACATACATTGAACCATCTGCAGCGGCACCCTCATGTCGTCCTCGCCAATATGTGAACCAGCATATAGGTGGGATATGCAGTTTAGTTGATGTAACCTTCCTCGGCTGTTGCCCTCCAACATCACAAATGTGGTCGTATATGTCTTGTGGTATTTTCTCCTTTAAAAGTCCAAGAAATCTTTAAAATAAGCAGTCACCTGGAGAATAACAGCAATTATGCAAGGCTACAGTGATAAAGGACAACTCACATACATACACACGCACACGCACAAACGCATCGTTCTATGCACCTGGAATATCTCGGAGCCACGTGGGATGCAGTGGAATCTCTTTACTTGTGTATCTATGGCAAGAAGTTGGTTTAATGTAAAGGTCTGGCAGAGAGCAATATCAAGTATGTGCAGATTAATACCTAAGCTTTGTACGGATGACCACTCACTCTACAGGATCTAAGCATAAAGCTGACATAATTGATTGCATCTAAGAAGTATCTTCTCCGACAGGCTGGCTTTTATTATTATTTCATAATTAAGAGTTGTTTTGAATGGTGCAAACATGCAGATGTGGTGAAGTGCTTTGGGCAATCATGAATATTTTCTTGGACAATTGAGGGAATTGCAGGGAGTTGCCTACTAGCTCGAACTACAGGTTTGGGGTTTTTTTTGGTTTGTTTTGTTTTTTGGGTTTTTTGTTTGTTTGTTTTTTTGAGATCATATATGTGTATGGTATCTATATATAGTCAATTGTGTTTATAGCACATACACGTGTCTGGTCCAAGGGTATGGCATTGCTCTCCATCTTCCTCTTTGAAGCATTGTCTCACCTAGGGGTGGTCAATAAGTTTGGGTCTGGTTAATGCCATGGTATGTGACGTTTTTATTTATTTGCAAGTCTTAACATTTAGTTTAAAAATAAAGAACACCACCACTGCAGTATGTCTGGCCTGGCTAGTCTAGCACTCAGACTTGTGCTGCAGTGCCTCATCTAACCAGTTCTCTCTCTCCAGTTCTTAAAAGGTCTCGGCAGGTTATGGTGGTGATTGACAGAGCCTGTGGTATTCTGTTCCTGCTAAGCAGAAACAGAATGCTTGGTTTTTGTTTAGCTTAGCCTACATTTGTGTTTGATCCACGTTGTTTCTAGCTAACGTCCACTCTACTTGTTCTTTAG
Seq C2 exon
GTGTTAAAAATGGACCAGGGCGGCCAGATCCTTCAGACAGCTCTTGCACAGGCCTTGTCAGACCTCAGCAGAAACCAAAGAAAAGTGAGAAAGAAGAAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000039842:ENSMUST00000039412:8
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.737 A=NA C2=0.931
Domain overlap (PFAM):
C1:
PF122583=Microcephalin=WD(100=99.5)
A:
NA
C2:
NO
Other Inclusion Isoforms:
NA
Associated events
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types