RnoEX0029033 @ rn6
Exon Skipping
Gene
ENSRNOG00000033835 | Dnm1
Description
dynamin 1 [Source:RGD Symbol;Acc:71096]
Coordinates
chr3:11338083-11342650:-
Coord C1 exon
chr3:11342409-11342650
Coord A exon
chr3:11341847-11342062
Coord C2 exon
chr3:11338083-11338671
Length
216 bp
Sequences
Splice sites
3' ss Seq
TCCGCTCTTGTCGCCCGTAGGTC
3' ss Score
12.01
5' ss Seq
CAGGTGAGT
5' ss Score
10.67
Exon sequences
Seq C1 exon
ACCAAGGAGTTTATCTTCTCTGAGCTGCTGGCCAACCTGTACTCTTGCGGGGACCAGAACACGCTGATGGAAGAATCGGCCGAACAGGCTCAGCGGCGCGACGAGATGCTGCGTATGTACCACGCACTGAAGGAGGCGCTCAGCATTATCGGCGACATCAACACGACCACCGTCAGCACGCCCATGCCCCCGCCCGTGGACGACTCCTGGCTGCAGGTGCAGAGCGTACCGGCCGGACGCAG
Seq A exon
GTCGCCCACGTCCAGCCCCACGCCGCAGCGCCGAGCCCCCGCCGTGCCCCCAGCCCGGCCCGGGTCGCGGGGCCCTGCTCCTGGGCCTCCGCCTGCTGGATCCGCCCTGGGGGGGGCTCCCCCCGTGCCCTCCAGGCCGGGGGCTTCCCCTGACCCCTTTGGCCCCCCTCCCCAGGTGCCCTCGCGCCCCAACCGCGCCCCGCCTGGGGTCCCCAG
Seq C2 exon
CCGATCGGGTCAGGCAAGTCCGTCCCGTCCTGAGAGCCCCAGGCCCCCCTTCGACCTCTAACCAGATCCCTCCTACTCCTCGGAGACCTCCCTTATCAAGCCTGCCTGGACAGCTGTTCTGTGACTTGACAGTGGCTCCCCCGACCCCAAAGCGTCCTATTCATCATCTGTGACTTAGTCTGTTGTAGTGGTGAGCTGATACATCCAAATGTGATGTTGGTGAAAACTTGTGCCCCTCTGTGGTATTGCTCCTGCGACATTCTATAAATATCTATAAATATACCTATATATACATATATATACATATATATGGCTGACACAGCCTCGCCTGTAGTGTCAGAATCAACCACCATGCTGTCCTTGTGGAGTCCTGTGGTCCAACTACAAGGGAACGCTGTCATCCTGACATCCCCCCTCCAATGTGCCACCTCCAGTGAGCCTCCCTGTCCCTTGGCCTGTGGACAGCCATCCCCTTGGCCATCCCCACCCTGCACAAGGGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSRNOG00000033835-'44-50,'44-44,46-50
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.630 A=1.000 C2=1.000
Domain overlap (PFAM):
C1:
PF0221213=GED=PD(56.5=64.2)
A:
NO
C2:
NO
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Mouse
(mm9)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACACGCTGATGGAAGAATCGG
R:
GTCCAGGCAGGCTTGATAAGG
Band lengths:
295-511
Functional annotations
There are 2 annotated functions for this event
PMID: 9148966
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: mutation analysis. ELM ID: ELMI000178; ELM sequence: PSRPNR; Overlap: FULL
PMID: 21689596
Partially encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: competition binding, glutathione s tranferase tag, mutation analysis, pull down. ELM ID: ELMI002614; ELM sequence: VPRITIS; Overlap: PARTIAL_RIGHT
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]