DreEX6008890 @ danRer10
Exon Skipping
Gene
ENSDARG00000010042 | dnm1a
Description
dynamin 1a [Source:ZFIN;Acc:ZDB-GENE-081104-27]
Coordinates
chr5:1352369-1363930:+
Coord C1 exon
chr5:1352369-1352610
Coord A exon
chr5:1352814-1353020
Coord C2 exon
chr5:1363884-1363930
Length
207 bp
Sequences
Splice sites
3' ss Seq
TGCCTATATTTTCCTGTCAGGTC
3' ss Score
9.77
5' ss Seq
CAGGTGAGA
5' ss Score
9.22
Exon sequences
Seq C1 exon
ACAAAGGAGTACATCAACGCGGAGCTGCTGGCTTCACTGTACTCGTGTGGAGATCAGAACACACTGATGGAGGAGTCTGCTGAGCAGGCGCAGCGGCGGGACGAGATGCTCCGCATGTACCACGCTCTCAAAGAGGCGCTCAACATCATTGGGGACATCAGCACCACCACCATCTCCACCTCTCTGCCTCCACCCGTGGACGACTCCTGGCTACAGGTGCAGCGCACTGGCTCTGGAGGAAG
Seq A exon
GTCTCCGGCCACCAGCCCAACCCCTCAAAGACGGGCTCCACCTCCAGGGCCTCCAGCTCGCCCAGGTTCCCGTGGTTCGGCCCCAGGGCCCCCAGCTGCAGGTGGGCCACCTGTTCCCTCCCGCCCCGGAGCCTCTCCGGACCCCTTCGGCGGACCTCCTCCTACGGTCCCATCCCGTCCTAACCGCGCCCCACCCAGTGTGCCCAG
Seq C2 exon
TGGTCCCTGAGCTTACGGGCCAGAAGACGACACCAAATTCCTGAAGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000010042-'27-29,'27-25,28-29=AN
Average complexity
A_C1
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.613 A=1.000 C2=1.000
Domain overlap (PFAM):
C1:
PF0221213=GED=PD(56.5=64.2)
A:
NO
C2:
NO
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Mouse
(mm9)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AAGGAGTACATCAACGCGGAG
R:
CCTTCAGGAATTTGGTGTCGTCT
Band lengths:
286-493
Functional annotations
There are 2 annotated functions for this event
PMID: 9148966
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: mutation analysis. ELM ID: ELMI000178; ELM sequence: PSRPNR; Overlap: FULL
PMID: 21689596
Partially encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: competition binding, glutathione s tranferase tag, mutation analysis, pull down. ELM ID: ELMI002614; ELM sequence: VPRITIS; Overlap: PARTIAL_RIGHT
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]