DreEX0027748 @ danRer10
Exon Skipping
Gene
ENSDARG00000010042 | dnm1a
Description
dynamin 1a [Source:ZFIN;Acc:ZDB-GENE-081104-27]
Coordinates
chr5:1352814-1363930:+
Coord C1 exon
chr5:1352814-1353020
Coord A exon
chr5:1358592-1358628
Coord C2 exon
chr5:1363884-1363930
Length
37 bp
Sequences
Splice sites
3' ss Seq
ATATGGATTATTTTTCACAGAAT
3' ss Score
5.29
5' ss Seq
CTGGTACGT
5' ss Score
9.57
Exon sequences
Seq C1 exon
GTCTCCGGCCACCAGCCCAACCCCTCAAAGACGGGCTCCACCTCCAGGGCCTCCAGCTCGCCCAGGTTCCCGTGGTTCGGCCCCAGGGCCCCCAGCTGCAGGTGGGCCACCTGTTCCCTCCCGCCCCGGAGCCTCTCCGGACCCCTTCGGCGGACCTCCTCCTACGGTCCCATCCCGTCCTAACCGCGCCCCACCCAGTGTGCCCAG
Seq A exon
AATTACAATCAGTGACCAATGAGGACTAACGCTTCTG
Seq C2 exon
TGGTCCCTGAGCTTACGGGCCAGAAGACGACACCAAATTCCTGAAGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000010042_MULTIEX2-2/3=C1-3
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=1.000 A=1.000 C2=1.000
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Main Inclusion Isoform:
ENSDART00000168130fB2363
Other Inclusion Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTCTCCGGACCCCTTCGG
R:
ATTTGGTGTCGTCTTCTGGCC
Band lengths:
113-150
Functional annotations
There are 1 annotated functions for this event
PMID: 21689596
Partially encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: competition binding, glutathione s tranferase tag, mutation analysis, pull down. ELM ID: ELMI002614; ELM sequence: VPRITIS; Overlap: PARTIAL_LEFT
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]