RnoEX6015363 @ rn6
Exon Skipping
Gene
ENSRNOG00000006338 | Lrp6
Description
LDL receptor related protein 6 [Source:RGD Symbol;Acc:1304749]
Coordinates
chr4:168231014-168235322:-
Coord C1 exon
chr4:168235033-168235322
Coord A exon
chr4:168233559-168233785
Coord C2 exon
chr4:168231014-168231198
Length
227 bp
Sequences
Splice sites
3' ss Seq
TGCAAATTTTATTTTTGCAGACT
3' ss Score
7.92
5' ss Seq
AGGGTAAAT
5' ss Score
5.83
Exon sequences
Seq C1 exon
GTTCTAACCCCTGTGCTGAGGAGAATGGAGGATGTAGCCATCTTTGCCTCTACAGGCCTCAGGGACTTCGATGTGCCTGTCCCATTGGCTTTGAGCTCATTAGTGACATGAAGACATGCATTGTTCCTGAGGCTTTCCTTCTGTTCTCACGGAGAGCAGATATAAGACGCATCTCTTTGGAAACAAACAACAACAATGTGGCCATTCCTCTCACGGGTGTCAAAGAAGCTTCTGCTTTGGATTTTGATGTCACAGACAACAGAATTTACTGGACCGATATATCCCTGAAG
Seq A exon
ACTATTAGCAGAGCTTTTATGAATGGCAGTGCACTGGAACATGTGGTAGAGTTCGGCTTAGATTACCCAGAAGGCATGGCAGTGGACTGGCTTGGGAAGAACTTATACTGGGCAGACACAGGAACAAATCGCATTGAGGTGTCAAAGTTGGATGGACAGCACCGACAGGTTTTGGTATGGAAAGACCTTGACAGTCCCCGAGCTCTGGCATTGGATCCTGCTGAAGG
Seq C2 exon
ATTTATGTATTGGACTGAGTGGGGAGGGAAGCCTAAGATTGACAGAGCGGCTATGGATGGAAGTGAACGCACTACATTAGTTCCAAATGTGGGTCGAGCAAATGGCCTTACCATCGACTATGCTAAGAGGCGGCTTTACTGGACAGACCTGGACACTAACTTAATAGAATCTTCAAATATGCTCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSRNOG00000006338-'11-16,'11-14,12-16=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.063
Domain overlap (PFAM):
C1:
PF146701=FXa_inhibition=WD(100=37.1),PF0005812=Ldl_recept_b=PU(24.4=10.3)
A:
PF0005812=Ldl_recept_b=PD(70.7=38.2),PF0005812=Ldl_recept_b=WD(100=53.9),PF0005812=Ldl_recept_b=PU(0.1=0.0)
C2:
PF0005812=Ldl_recept_b=WD(100=65.1),PF0005812=Ldl_recept_b=PU(51.4=30.2)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCTTCTGTTCTCACGGAGAGC
R:
CCAGTAAAGCCGCCTCTTAGC
Band lengths:
296-523
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]