DreEX6101261 @ danRer10
Exon Skipping
Gene
ENSDARG00000006921 | lrp5
Description
low density lipoprotein receptor-related protein 5 [Source:ZFIN;Acc:ZDB-GENE-050518-2]
Coordinates
chr25:10574897-10579391:-
Coord C1 exon
chr25:10579102-10579391
Coord A exon
chr25:10576832-10577058
Coord C2 exon
chr25:10574897-10575081
Length
227 bp
Sequences
Splice sites
3' ss Seq
TGATCTCGTTTCTCCTCCAGACC
3' ss Score
9.71
5' ss Seq
CGGGTACAG
5' ss Score
4.22
Exon sequences
Seq C1 exon
GTACCAACGGCTGTGCCGAAAACAACGGCGGCTGCAGTCACCTGTGCTTCCATCGGCCGCAGGGTCTGAGCTGCGCCTGTCCCATGGGCCTTGAGCTGCTGAGCGACCTGCGCACATGTGTGGTTCCTGAAGCCTTCCTGCTGTTCACCAACCGTGCCGACATCCGCAGCATCTCTCTGGGCACCAACAGCAACGACGTGCCCATCCCGCTGACCGGCGTCAAAGAAGCGTCCGCGCTCGACTTCGATGTTTTAGAGAACAGAATCTACTGGACTGACGTCAGCACCAAG
Seq A exon
ACCATCAGCAGAGCGTTCATGAATGGCAGCTCAGTTGAACCCGTCATCGAGTTCGGTCTGGACTATCCCGAGGGAATGGCAGTGGACTGGATGGGCAGAAATCTCTACTGGGCAGATACTGGCACCAACCGCATCGAAGTGGCCCGTCTGGACGGCCAGTACCGGCAAGTGCTGGTCTGCAAAGATCTGGATAACCCTCGATCGCTCGCTCTGGATCCTGCCAACGG
Seq C2 exon
GTACATGTACTGGACTGAATGGGGAGGTCGACCCAGGATTGCTCGCGCTCACATGGACGGCAGTAACATCGTGACTCTGGTGGATAAAGTGGGACGAGCAAACGGACTCACCATTGACTATATCGACCAGCGGCTGTACTGGACAGACCTGGACACATGCATGATCGAGTCCACAAACATGCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000006921-'12-17,'12-16,13-17=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF146701=FXa_inhibition=WD(100=37.1),PF0005812=Ldl_recept_b=PU(24.4=10.3)
A:
PF0005812=Ldl_recept_b=PD(70.7=38.2),PF0005812=Ldl_recept_b=WD(100=53.9),PF0005812=Ldl_recept_b=PU(0.1=0.0)
C2:
PF0005812=Ldl_recept_b=WD(100=65.1),PF0005812=Ldl_recept_b=PU(51.4=30.2)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTGGTTCCTGAAGCCTTCCTG
R:
ACAGCCGCTGGTCGATATAGT
Band lengths:
308-535
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]