RnoEX6005906 @ rn6
Exon Skipping
Gene
ENSRNOG00000015911 | Lrp5
Description
LDL receptor related protein 5 [Source:RGD Symbol;Acc:1309329]
Coordinates
chr1:218848676-218855797:-
Coord C1 exon
chr1:218855508-218855797
Coord A exon
chr1:218850355-218850581
Coord C2 exon
chr1:218848676-218848860
Length
227 bp
Sequences
Splice sites
3' ss Seq
TTTCTTCTGCACCCTCTCAGACT
3' ss Score
7.6
5' ss Seq
AGGGTAAGG
5' ss Score
9.16
Exon sequences
Seq C1 exon
GAACCAACCCGTGTGCGGATGGAAATGGAGGGTGCAGCCATCTGTGCTTCTTCACCCCACACGCCACCAAGTGCGGTTGCCCCATAGGCCTGGAGCTGCTGAGTGACATGAAGACCTGTATAATCCCTGAAGCCTTCCTGGTGTTCACCAGCAGAGCCACCATCCACAGGATCTCCCTGGAGACTAACAACAATGACGTGGCCATCCCGCTCACCGGTGTCAAGGAGGCCTCTGCACTGGACTTTGATGTGTCCAACAACCACATCTACTGGACTGATGTCAGCCTCAAG
Seq A exon
ACTATCAGCCGAGCCTTCATGAATGGGAGCTCAGTGGAGCACGTGATTGAGTTTGGCCTCGACTACCCTGAAGGAATGGCCGTGGATTGGATGGGCAAGAACCTCTATTGGGCTGACACGGGGACCAACAGGATTGAGGTGGCCCGACTGGATGGGCAGTTCCGGCAGGTGCTGGTGTGGAGAGACCTTGACAACCCCAGGTCGCTGGCTCTGGATCCTACTAAAGG
Seq C2 exon
CTACATCTACTGGACCGAGTGGGGAGGCAAGCCAAGGATCGTGCGGGCCTTCATGGATGGGACCAATTGTATGACACTGGTAGACAAGGTGGGCCGGGCCAATGACCTCACCATTGATTACGCCGACCAGCGACTGTACTGGACTGACCTGGACACCAACATGATTGAGTCCTCCAACATGCTGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSRNOG00000015911-'18-14,'18-13,20-14=AN
Average complexity
A_C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF146701=FXa_inhibition=WD(100=37.1),PF0005812=Ldl_recept_b=PU(24.4=10.3)
A:
PF0005812=Ldl_recept_b=PD(70.7=38.2),PF0005812=Ldl_recept_b=WD(100=53.9),PF0005812=Ldl_recept_b=PU(0.1=0.0)
C2:
PF0005812=Ldl_recept_b=WD(100=65.1),PF0005812=Ldl_recept_b=PU(51.4=30.2)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGATGGAAATGGAGGGTGCAG
R:
CCCACTCGGTCCAGTAGATGT
Band lengths:
297-524
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]