RnoEX6060452 @ rn6
Exon Skipping
Gene
ENSRNOG00000020151 | Cdh1
Description
cadherin 1 [Source:RGD Symbol;Acc:69279]
Coordinates
chr19:38832633-38834849:+
Coord C1 exon
chr19:38832633-38832860
Coord A exon
chr19:38833907-38834037
Coord C2 exon
chr19:38834706-38834849
Length
131 bp
Sequences
Splice sites
3' ss Seq
CCTCCCTTCCCTGTCTCCAGTTC
3' ss Score
10.47
5' ss Seq
CAGGTGGGT
5' ss Score
8.56
Exon sequences
Seq C1 exon
AACAAGAATCTCTCATTTTGCAACCAAGAAAGGACTTAGAGATTGGCGAATACAAAATCAATCTCAAGCTCTCGGATAACCAGAATAAAGACCAGGTGACCACGTTGGAGGTCCACGTGTGTGACTGTGAAGGGACCGTCAACAACTGCATGAAGGCGATCTCCCTGGAAGCAGGATTACAAGTTCCCGCCATCCTTGGAATCCTGGGAGGGATCCTGGCCCTCCTGA
Seq A exon
TTCTGATCCTCCTGCTCCTACTGTTTCTACGGAGGAGAACGGTGGTCAAAGAGCCCTTGCTGCCACCAGATGACGATACCCGGGACAATGTGTATTACTATGATGAAGAGGGAGGTGGAGAAGAAGACCAG
Seq C2 exon
GACTTTGATTTGAGCCAGCTGCACAGGGGCCTTGATGCCAGACCGGAAGTGATTCGAAATGATGTGGCTCCCACCCTCATGAGCATGCCCCAGTATCGTCCCCGTCCAGCCAATCCTGATGAAATCGGGAACTTCATCGATGAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSRNOG00000020151-'20-15,'20-14,21-15=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.364 C2=0.542
Domain overlap (PFAM):
C1:
PF0002812=Cadherin=PD(44.9=51.9)
A:
PF0104912=Cadherin_C=PU(22.3=75.0)
C2:
PF0104912=Cadherin_C=FE(31.8=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CGTGTGTGACTGTGAAGGGAC
R:
CCCGATTTCATCAGGATTGGCT
Band lengths:
242-373
Functional annotations
There are 1 annotated functions for this event
PMID: 11076937
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: cleavage reaction, confocal microscopy, edman degradation, western blot. ELM ID: ELMI001928; ELM sequence: DTRDN; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]