FBgn0000667 @ dm6
Biotype
protein_coding
Gene Symbol
Actn
Description
The gene alpha actinin is referred to in FlyBase by the symbol DmelActn (CG4376, FBgn0000667). It is a protein_coding_gene from Dmel. It has 10 annotated transcripts and 10 polypeptides (4 unique). Gene sequence location is X:2023822..2042311. Its molecular function is described by: protein binding; actin filament binding; calcium ion binding; actin binding. It is involved in the biological process described with: sarcomere organization; actin filament bundle assembly; actin cytoskeleton reorganization. 48 alleles are reported. The phenotypes of these alleles manifest in: non-connected functional system; larva; somatic muscle; sensory system; pericardial cell. The phenotypic classes of alleles include: increased mortality; phenotype; some die during pupal stage; visible. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed within 12-24 hour embryonic stages, at stages throughout the larval period, during late pupal stages, in stages of adults of both sexes.
Coordinates
chrX:2023822-2042311:-
Assembly
GENOMIC BROWSER[edit]
EXPRESSION VALUES[edit]
SPECIAL DATASETS
- Neural diversity
- Neurogenesis
- Neuronal activity
- Splicing factor regulation (brain)
- Splicing factor regulation (SL2)
EVENTS AND AS PROFILES[edit]
Associated events[edit]
Event
Type
Length
Coordinates
Strand
PSI Average
PSI Range
Annotated Functions
Orthologous genes[edit]
| Organism | Assembly | Gene ID | Gene Name | Orthology Type
|
|---|---|---|---|---|
| Human | hg38 | ENSG00000072110 | ACTN1 | 1-to-4 |
| Human | hg38 | ENSG00000077522 | ACTN2 | 1-to-4 |
| Human | hg38 | ENSG00000130402 | ACTN4 | 1-to-4 |
| Human | hg38 | ENSG00000248746 | ACTN3 | 1-to-4 |
| Human | hg19 | ENSG00000072110 | ACTN1 | 1-to-4 |
| Human | hg19 | ENSG00000077522 | ACTN2 | 1-to-4 |
| Human | hg19 | ENSG00000130402 | ACTN4 | 1-to-4 |
| Human | hg19 | ENSG00000248746 | ACTN3 | 1-to-4 |
| Mouse | mm10 | ENSMUSG00000006457 | Actn3 | 1-to-4 |
| Mouse | mm10 | ENSMUSG00000015143 | Actn1 | 1-to-4 |
| Mouse | mm10 | ENSMUSG00000052374 | Actn2 | 1-to-4 |
| Mouse | mm10 | ENSMUSG00000054808 | Actn4 | 1-to-4 |
| Mouse | mm9 | ENSMUSG00000006457 | Actn3 | 1-to-4 |
| Mouse | mm9 | ENSMUSG00000015143 | Actn1 | 1-to-4 |
| Mouse | mm9 | ENSMUSG00000052374 | Actn2 | 1-to-4 |
| Mouse | mm9 | ENSMUSG00000054808 | Actn4 | 1-to-4 |
| Rat | rn6 | ENSRNOG00000017833 | Actn2 | 1-to-4 |
| Rat | rn6 | ENSRNOG00000019745 | Actn3 | 1-to-4 |
| Rat | rn6 | ENSRNOG00000020433 | Actn4 | 1-to-4 |
| Rat | rn6 | ENSRNOG00000056756 | Actn1 | 1-to-4 |
| Cow | bosTau6 | ENSBTAG00000009696 | ACTN2 | 1-to-4 |
| Cow | bosTau6 | ENSBTAG00000011215 | ACTN4 | 1-to-4 |
| Cow | bosTau6 | ENSBTAG00000018255 | ACTN1 | 1-to-4 |
| Cow | bosTau6 | ENSBTAG00000022244 | ACTN3 | 1-to-4 |
| Chicken | galGal4 | ENSGALG00000014463 | ACTN2 | 1-to-4 |
| Chicken | galGal3 | ENSGALG00000014463 | ACTN2_CHICK | 1-to-4 |
| Zebrafish | danRer10 | ENSDARG00000001431 | actn3b | 1-to-6 |
| Zebrafish | danRer10 | ENSDARG00000007219 | actn1 | 1-to-6 |
| Zebrafish | danRer10 | ENSDARG00000013755 | actn3a | 1-to-6 |
| Zebrafish | danRer10 | ENSDARG00000071090 | actn2b | 1-to-6 |
| Zebrafish | danRer10 | ENSDARG00000099786 | ACTN4 | 1-to-6 |